1. Recombinant Proteins
  2. Cytokines and Growth Factors CD Antigens
  3. TNF Superfamily B Cell CD Proteins Macrophage CD Proteins
  4. TNF Superfamily Ligands CD257/BAFF
  5. B-cell Activating Factor (BAFF)
  6. BAFF/TNFSF13B Protein, Human (CHO)

BAFF/TNFSF13B Protein, Human (CHO)

Cat. No.: HY-P7003
Handling Instructions

BAFF/TNFSF13B Protein, Human (CHO) is a member of the tumor necrosis factor (TNF) superfamily, and plays an essential role in peripheral B-cell homeostasis.

For research use only. We do not sell to patients.

Protein Expression Service

Size Price Stock Quantity
10 μg $90 In-stock
Estimated Time of Arrival: December 31
50 μg $290 In-stock
Estimated Time of Arrival: December 31
100 μg $490 Get quote
250 μg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

  • References

Description

BAFF/TNFSF13B Protein, Human (CHO) is a member of the tumor necrosis factor (TNF) superfamily, and plays an essential role in peripheral B-cell homeostasis.

Background

B-cell activating factor (BAFF), a member of the tumor necrosis factor (TNF) superfamily, is secreted by various myeloid cells such as macrophages, dendritic cells, and neutrophils. BAFF is a potent survival factor for B cells and plays an essential role in peripheral B-cell homeostasis[1].

Biological Activity
The ED50 is <20 ng/mL as measured by human RPMI 8226 cells, corresponding to a specific activity of >5.0 × 104 units/mg.
Species

Human

Source

CHO

Accession

Q9Y275 (A134-L285)

Gene ID
Synonyms
rHuBAFF/TNFSF13B; BLYS; TALL1; THANK; ZTNF4; TALL-1; TNFSF20
AA Sequence

AVQGPEETVTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKILVKETGYFFIYGQVLYTDKTYAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLPNNSCYSAGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKLL

Molecular Weight

Approximately 17 kDa

Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O or PBS.

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation
References
  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Active Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific active calculator equation

Specific Active (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Active (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
BAFF/TNFSF13B Protein, Human (CHO)
Cat. No.:
HY-P7003
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