Membrane Protein-targeted Compound Library

Cat. No.: HY-L149: Library Contents: XLSX PDF SDF

A membrane protein is a protein molecule that is attached to or associated with the membrane of a cell or an organelle. Membrane proteins can be classified into two groups based on how the protein is associated with the membrane: integral membrane proteins and peripheral membrane proteins. In humans, about 30% genome encodes membrane proteins. Membrane proteins perform a variety of functions vital to the survival of organisms, for example, signal transduction, molecules or ion transportation, enzymatic catalysis, and intercellular communication. Membrane proteins also play important roles in drug discovery. As reported, more than 60% of current drug targets are membrane proteins.

MCE supplies a unique collection of 6853 compounds targeting a variety of membrane proteins. MCE Membrane Protein-targeted Compound Library can be used for membrane protein-focused screening and drug discovery.

MCE Membrane Protein-targeted Compound Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 6735 compounds supplied in 10 mM solution, 110 compounds supplied in 2 mM solution and 8 compounds supplied in 3 mg/mL solution.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

Size (Pre-dissolved Solution or Solid)	Price	Stock
30 μL/well Solution 10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution	Get quote	In-stock
50 μL/well Solution 10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution	Get quote	In-stock
100 μL/well Solution 10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution	Get quote	In-stock
2 × 100 μL/well Solution 10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution	Get quote	In-stock

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Publications Citing Use of MCE Compound Libraries

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Description & Advantages	• A unique collection of 6853 small molecules targeting variety of membrane proteins. • Targets such as GLUT, GABA Receptor, VEGFR, GPR88, Adrenergic Receptor, 5-HT Receptor, ion channel, etc. • All of the small molecules in this library are well characterized with biological and pharmaceutical activity. Some compounds have been approved by the FDA. • A powerful tool for discovering membrane protein-based drugs. • Structurally diverse, medicinally active, and cell permeable. • NMR and HPLC validated to ensure the highest purity. • All compounds are in stock and continuously updated.
Product Details	Formulation: A collection of 6853 membrane proteins-related compounds supplied as pre-dissolved Solutions or Solid. Solution: 6735 compounds supplied in 10 mM solution, 110 compounds supplied in 2 mM solution, 8 compounds supplied in 3 mg/mL solution. Layout: 96-well storage tube or 96-well plate: 1st and 12th column are left empty. 384-well plate: the first two columns and the last two columns are left empty. Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations. If you have other requirements, please let us know. Container: 96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode. Storage: In solvent: -80°C 2 years, -20°C 1 year; Powder: -20°C 3 years, 4°C 2 years Shipping: Blue ice or dry ice
Documentation	XLSX PDF Library Handling Instructions (351 KB)

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Membrane Protein-targeted Compound Library

Publications Citing Use of MCE Compound Libraries

Description

Product Details

Documentation

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