1. MCE Kits
  2. Cell Biology
  3. 3D Cell Culture
  4. PSC Induction Product Series

PSC Induction Product Series

FAQ

PSC Induction Product Series are professional induction and culture systems developed based on the principles of directed differentiation of pluripotent stem cells (PSCs). These products enable the efficient and stable differentiation of human- or animal-derived PSCs into organoids or into specific lineage-committed cell types. By scientifically combining key signaling pathway modulators and applying stage-specific induction strategies, this product series precisely recapitulates development and differentiation processes in vivo, effectively promoting the directed differentiation and maturation of PSCs into target cell types. The PSC Induction Product Series is suited for applications in developmental biology research, disease modeling, drug screening, and regenerative medicine.

Cat. No.
Name
Description
  • HY-K6021 CEPT Cocktail Plus (1000×)

    MCE CEPT Cocktail Plus (1000×) is a composite supplement specifically formulated for pluripotent stem cell culture. Through synergistic effects, it inhibits oxidative damage, blocks apoptotic pathways, and regulates protein translation, significantly reducing cellular stress levels through multiple targets. This dramatically improves the survival rate and cloning efficiency of pluripotent stem cells.

    HY-K6023 Cardiomyocyte Dissociation Kit

    MCE ECM Gentle Dissociation Solution is a gentle ECM-degrading enzyme mixture derived from marine bacteria and Bacillus species, specifically formulated for efficient and low-damage digestion of in-vitro cell systems. It selectively degrades extracellular matrix components while minimizing disruption to the cell membrane and intercellular junctions, thereby significantly reducing mechanical stress during dissociation.

    HY-K6301 Human iPSC/ESC Cortical Brain Organoid Induction Differentiation Kit

    MCE Human iPSC/ESC Cortical Brain Organoid Induction Differentiation Kit is a standardized culture system specifically designed to recapitulate the developmental processes and functional features of the human cerebral cortex through forebrain ventralization-based signaling regulation. By sequentially activating the Wnt/β-catenin pathway and gradually inhibiting BMP/Smad signaling, this system efficiently drives human pluripotent stem cells (PSC) to differentiate into high-purity glutamatergic neurons (VGLUT1/2+ > 85%), while simultaneously promoting the formation of Pax6+/BLBP+ radial glial cells that establish a biomimetic ventricular-zone–like structure.

    HY-K6302 Human iPSC/ESC Whole-Brain Organoid Induction Differentiation Kit

    MCE Human iPSC/ESC Whole-Brain Organoid Induction Differentiation Kit is a non-region-specific brain organoid induction kit designed based on the neuroectoderm self-differentiation system. After 38 d of culture using this kit, the resulting whole-brain organoids stably express core neuronal markers such as TUJ1, SOX2, Nestin, and NeuN, as well as forebrain/cortical markers including FOXG1 and CTIP2.

    HY-K6303 Human iPSC/ESC Cardiomyocyte Induction Differentiation Kit

    MCE Human iPSC/ESC Cardiomyocyte Induction Differentiation Kit is based on the classical GiWi system. By precisely modulating the Wnt/β-catenin signaling pathway in a temporally controlled manner (sequential activation and inhibition), the kit enables highly efficient directed differentiation of human pluripotent stem cells into cardiomyocytes. It is suitable for cardiac disease modeling, drug cardiotoxicity assessment, and mechanistic studies.

    HY-K6304 Human iPSC/ESC Hepatocyte Induction Differentiation Kit

    MCE Human iPSC/ESC Hepatocyte Induction Differentiation Kit enables the efficient generation of hepatocyte-like cells with a high degree of maturation within 21 d. The resulting cells stably express multiple key hepatic functional markers, including albumin (ALB), cytochrome P450 (CYP) family enzymes, and other liver-specific functional molecules, and exhibit typical hepatocellular phenotypes and functions.

    HY-K6501 Human PSC Maintenance Medium

    MCE Human PSC Maintenance Medium is a ready-to-use, chemically defined formulation designed to support the robust growth and self-renewal of human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) under feeder-free culture conditions.

    HY-K6502 Human iPSC-Derived Brain Organoid Long-term Culture Medium

    MCE Human iPSC-Derived Brain Organoid Long-term Culture Medium is a specialized culture system developed through systematic reformulation and concentration optimization based on neuronal cell culture platforms. It significantly enhances the adaptability and stability of long-term culture for brain organoids derived from human induced pluripotent stem cells (iPSCs).

    HY-K6503 Human PSC Embryoid Body (EB) Induction Medium

    MCE Human PSC Embryoid Body (EB) Induction Medium is specifically designed to support the efficient and reproducible formation of uniform embryoid bodies from pluripotent stem cells under suspension culture conditions. This optimized culture system integrates microenvironmental regulation with metabolic adaptation strategies, significantly improving the stability and reproducibility of EB formation.

    HY-K6504 Human iPSC/ESC Cortical Brain Organoid Maturation Medium

    MCE Human iPSC/ESC Cortical Brain Organoid Maturation Medium is a ready-to-use culture system specifically formulated for the long-term maintenance and maturation of cortical brain organoids. It serves as a seamless transition from the induction phase and supports the continued growth and functional development of the organoids. Upon switching PSC-derived cortical brain organoids to this medium, organoid viability and structural stability are markedly enhanced, enabling a robust and extended culture period of up to 180 d.