MUC-24/CD164
MUC-24/CD164 is a transmembrane sialomucin encoded by the CD164 gene, historically known as MGC-24 or endolyn, with two mucin-like domains rich in sialylated and sulfated O-linked glycans. It localizes to endosomes and the cell surface and is expressed on hematopoietic progenitors, bone marrow stromal cells and subsets of lymphocytes and epithelial cells. Functionally, CD164 modulates adhesive and migratory interactions between hematopoietic stem cells and the stromal microenvironment and has been reported to restrain primitive progenitor proliferation while supporting quiescence. Its expression in acute myeloid leukemia and other malignancies has drawn interest as a marker of primitive, stem-like tumor compartments.
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MUC-24/CD164 Recombinant Proteins (5)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
