1. Recombinant Proteins
  2. Immune Checkpoint Proteins
  3. Inhibitory checkpoint molecules

Inhibitory checkpoint molecules

Inhibitory checkpoint molecules play an important role in the maintenance of immune homeostasis: their expression on effector T cells ensures the proper contraction of effector T cell responses; their expression on regulatory T (Treg) cells promotes the suppressive function of Tregs. Blockade of inhibitory immune checkpoint molecules has proven to enhance immune responses to various cancers and exhibit remarkable clinical efficacy in cancer treatment.

Cat. No. Product Name / Synonyms Species Source
  • HY-P72469
    SIRP alpha/CD172a Protein, Cynomolgus (339a.a, HEK293, His)

    Signal-regulatory protein alpha; CD172a; SIRP alpha; SIRPA; MFR; SHPS1; SIRP

    Human HEK 293
  • HY-P77235
    TIGIT Protein, Mouse (HEK293, mFc)

    T cell immunoreceptor with Ig and ITIM domains; TIGIT; VSIG9; VSTM3

    Mouse HEK 293
  • HY-P77468
    Nectin-1 Protein, Mouse (HEK293, Fc)

    Poliovirus Receptor-Related Protein 1; Herpes Virus Entry Mediator C; Herpesvirus Entry Mediator C; HveC; Herpesvirus Ig-Like Receptor; HIgR; Nectin-1; CD111; PVRL1; HVEC; PRR1

    Mouse HEK 293
  • HY-P70535
    Galectin-9/LGALS9 Protein, Human (355a.a, HEK293, His)

    Galectin-9; Gal-9; Ecalectin; Tumor Antigen HOM-HD-21; LGALS9

    Human HEK 293
  • HY-P7396
    PD-1 Protein, Human (143a.a, HEK293, His)

    rHuPD-1, His; PD1; CD279; PDCD1

    Human HEK 293
    PD-1 Protein, Human (143a.a, HEK293, His) suppress activating signals from the T cell receptor when bound by either of its ligands, programmed death-ligand 1 (PD-L1) or PD-L2.
  • HY-P70826
    TIM-3/HAVCR2 Protein, Mouse (172a.a, HEK293, Fc)

    Hepatitis A virus cellular receptor 2 homolog; HAVcr-2; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; Tim3; Timd3

    Mouse HEK 293
  • HY-P70632
    PD-L1 Protein, Mouse (HEK 293, His)

    Programmed cell death 1 ligand 1Cd274; programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; programmed death ligand 1; B7 homolog 1; B7-H1; CD274

    Mouse HEK293
  • HY-P70740
    FGL1 Protein, Human (HEK 293, mFc)

    Fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1

    Human HEK293
  • HY-P72637
    Galectin-9 Protein, Mouse (GST)

    Galectin-9; Lgals9; Gal-9

    Mouse E. coli
  • HY-P7395
    PD-1 Protein, Human (CHO, Fc)

    rHuPD-1, Fc Chimera; PD1; CD279; PDCD1

    Human CHO
    PD-1 Protein, Human (CHO, Fc) suppress activating signals from the T cell receptor when bound by either of its ligands, programmed death-ligand 1 (PD-L1) or PD-L2.
  • HY-P70633
    PD-L1 Protein, Mouse (220a.a, HEK 293, Fc)

    Programmed cell death 1 ligand 1Cd274; programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; programmed death ligand 1; B7 homolog 1; B7-H1; CD274;

    Mouse HEK293
  • HY-P70640
    PD-1 Protein, Mouse (HEK 293, His)

    Programmed cell death protein 1; PD-1; CD279; Pdcd1; mPD-1

    Mouse HEK293
  • HY-P73363
    PD-L1 Protein, Mouse (239a.a, HEK293, Fc)

    Programmed cell death 1 ligand 1; PD-L1; B7-H1; CD274; PDL1

    Mouse HEK293
  • HY-P73716
    PD-L1 Protein, Mouse (HEK293, His-Fc)

    Programmed cell death 1 ligand 1; PD-L1; B7-H1; CD274; PDL1

    Mouse HEK293
  • HY-P70734
    PD-L2 Protein, Human (HEK 293, mFc)

    Programmed Cell Death 1 Ligand 2; PD-1 Ligand 2; PD-L2; PDCD1 Ligand 2; Programmed Death Ligand 2; Butyrophilin B7-DC; B7-DC; CD273; PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2

    Human HEK293
  • HY-P7397
    PD-L1 Protein, Human (CHO, Fc)

    rHuPD-L1, Fc Chimera; Programmed death ligand 1; CD274; B7-H1

    Human CHO
    PD-L1 Protein, Human (CHO, Fc) play a major role in suppressing the adaptive arm of immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis.
  • HY-P7398
    PD-L1 Protein, Human (HEK293, His)

    rHuPD-L1, His; Programmed death ligand 1; CD274; B7-H1

    Human HEK 293
    PD-L1 Protein, Human (HEK293, His) play a major role in suppressing the adaptive arm of immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis.
  • HY-P7640
    B7-H4 Protein, Human (HEK293, Fc)

    rHuB7-H4, C-Fc; B7-H4; Protein B7S1; T cell costimulatory molecule B7x; V-set domain-containing T-cell activation inhibitor 1

    Human HEK 293
    B7-H4 Protein, Human (HEK293, Fc) may participate in negative regulation of cell-mediated immunity in peripheral tissues. Cell-associated B7-H4 could also inhibit T cell response. B7-H4 acts as a morphogenic factor for cancer cells.
  • HY-P70639
    PD-1 Protein, Mouse (HEK 293, Fc)

    Programmed cell death protein 1; PD-1; CD279; Pdcd1; mPD-1

    Mouse HEK293
  • HY-P70696
    Galectin-9 Protein, Human (HEK 293, GST)

    Galectin-9; Gal-9; Ecalectin; Tumor antigen HOM-HD-21; LGALS9; Gal-9delta5

    Human E. coli
Cat. No. Product Name Effect Purity