CAR-T Related Proteins
Chimeric antigen receptor T (CAR-T) cells, which are genetically engineered to express specific synthetic antigen receptors, can specifically target antigens and kill tumor cells. CAR-T cells are capable of specifically recognizing their target antigen through the single-chain fragment variable (scFv) binding domain, resulting in T cell activation in a major histocompatibility complex (MHC)-independent manner. Generally, CAR molecules are composed of 3 components: 1) an extracellular domain involved in antigen identification, which is composed of a scFv that (specifically) recognizes tumor-associated antigens (TAA). scFV is fixed on T cell by a 2) transmembrane domain, composed of a transmembrane region of CD3, CD8, CD28 or FcεRI. This region is connected to the 3) intracellular zone, composed of the intracytoplasmic region of CD8, CD28 or CD137 and CD3ζ. This zone comprises the immune receptor tyrosine-based activation motif (ITAM) which activates the costimulatory signal.
- c-Met/HGFR (48)
- ErbB2/HER2 (40)
- GPC-3 (21)
- TROP-2 (21)
- Siglec-3/CD33 (20)
- Epithelial Cell Adhesion Molecule (EpCAM) (17)
- CD314/NKG2D (17)
- CD4 (16)
- CD27 Ligand/CD70 (16)
- CD19 (15)
- ErbB3/HER3 (15)
- Folate Receptor alpha (FR-alpha) (15)
- CD7 (15)
- MUC-1/CD227 (14)
- CD138/Syndecan-1 (11)
- CA-125 (11)
- ROR1 (11)
- CD319/SLAMF7 (11)
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CAR-T Related Recombinant Proteins (538)
EGFR Protein, Human (Active, sf9, His-GST)
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Cat. No.: HY-P72987
Purity: ≥ 75%, as determined by reducing SDS-PAGE.
Synonyms: EGFR; Epidermal Growth Factor Receptor Variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell Growth Inhibiting Protein 40; ERRP; Receptor Protein-Tyrosine Kinase; Receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein E
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HER2/CD340 Protein, Human (HEK293)
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Cat. No.: HY-P73094
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ERBB2; P185erbB2; Prev. NGL; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog); HER2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2 Isoform C; Receptor Tyrosine-Protein Kinase ErbB-2; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2; Proto-Oncogene C-ErbB-2; Neuroblastoma/Glioblastoma Derived Oncogene Homolog; Proto-Oncogene Neu; Receptor Tyrosine-Protein Kinase ErbB-2 Variant; P185(ErbB2); Truncated HER2 Splice Variant P100; C-ERB-2; Receptor Protein-Tyrosine Kinase; C-ERB2; Metastatic Lymph Node Gene 19; MLN-19; Alternative Protein ERBB2; HER-2; C-Erb B2/Neu Protein; CD340; CD340 Antigen; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; HER-2/Neu; Tyrosine Kinase-Type Cell Surface Receptor HER2; Herstatin; Neuro/Glioblastoma Derived Oncogene Homolog; VSCN2; Human Epidermal Growth Factor Receptor 2; MLN19; Metastatic Lymph Node Gene 19 Protein; TKR1; Erb-B2 Receptor Tyrosine Kinase 2; MLN 19
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VEGFR-2 Protein, Human (HEK293, His)
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Cat. No.: HY-P70552
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KDR; Fetal Liver Kinase 1; Kinase Insert Domain Receptor; Vascular Endothelial Growth Factor Receptor 2 Variant; Vascular Endothelial Growth Factor Receptor 2; Tyrosine Kinase Growth Factor Receptor; VEGFR2; Receptor Protein-Tyrosine Kinase; FLK1; Fetal L
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TROP-2 Protein, Human (248a.a, HEK293, His)
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Cat. No.: HY-P70457
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TACSTD2; Epithelial Glycoprotein-1; Prev. M1S1; Membrane Component, Chromosome 1, Surface Marker 1; GA733-1; Gastrointestinal Tumor-Associated Antigen GA7331; TROP2; Pancreatic Carcinoma Marker Protein GA7331; Tumor-Associated Calcium Signal Transducer 2; Cell Surface Glycoprotein TROP2; EGP-1; Truncated TACSTD2; Membrane Component Chromosome 1 Surface Marker 1; GA7331; Pancreatic Carcinoma Marker Protein GA733-1; EGP1; Trophoblast Cell Surface Antigen 2; GP50; Cell Surface Glycoprotein Trop-2; Tumor Associated Calcium Signal Transducer 2; 40kD Glycoprotein, Identified By Monoclonal Antibody GA733
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EGFR Protein, Human (621a.a, HEK293, Fc)
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Cat. No.: HY-P74177
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EGFR; Epidermal Growth Factor Receptor Variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell Growth Inhibiting Protein 40; ERRP; Receptor Protein-Tyrosine Kinase; Receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein EGFR; Erb-B2 Receptor Tyrosine Kinase 1; Epidermal Growth Factor; Proto-Oncogene C-ErbB-1; EGFR VIII; HER1; NISBD2; Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog); NNCIS; Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian); PIG61; Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog; MENA; Epidermal Growth Factor Receptor Tyrosine Kinase Domain; Epidermal Growth Factor Receptor; Epidermal Growth Factor Receptor Variant EX12_15del
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CD19 Protein, Human (Biotinylated, HEK293, Fc-Avi)
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Cat. No.: HY-P78917
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD19; CDNA FLJ60916, Highly Similar To B-Lymphocyte Antigen CD19; CD19 Molecule; CDNA FLJ54955, Highly Similar To B-Lymphocyte Antigen CD19; B-Lymphocyte Surface Antigen B4; CD19 Antigen, Isoform CRA_f; T-Cell Surface Antigen Leu-12; CD19 Antigen, Isoform
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HER2/CD340 Protein, Human (Biotinylated, HEK293, His)
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Cat. No.: HY-P78882
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: ERBB2; P185erbB2; Prev. NGL; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog); HER2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; NEU;
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CA125 Protein, Human (HEK293, His)
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Cat. No.: HY-P7696
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MUC16; FLJ14303; Mucin 16, Cell Surface Associated; Mucin-16; CA125; CA125 Ovarian Cancer Antigen; CA-125; Mucin-16 Short Isoform; Ovarian Cancer-Related Tumor Marker CA125; Mucin-16 Long Isoform; Ovarian Carcinoma Antigen CA125; MUC-16; Cancer Antigen 12
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VEGFR-2 Protein, Human (745a.a, HEK293, Fc)
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Cat. No.: HY-P70635
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KDR; Fetal Liver Kinase 1; Kinase Insert Domain Receptor; Vascular Endothelial Growth Factor Receptor 2 Variant; Vascular Endothelial Growth Factor Receptor 2; Tyrosine Kinase Growth Factor Receptor; VEGFR2; Receptor Protein-Tyrosine Kinase; FLK1; Fetal L
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EGFR Protein, Human (621a.a, CHO, His)
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Cat. No.: HY-P7340
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EGFR; Epidermal Growth Factor Receptor Variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell Growth Inhibiting Protein 40; ERRP; Receptor Protein-Tyrosine Kinase; Receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein E
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CD20/MS4A1 Protein-VLP, Human (HEK293)
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Cat. No.: HY-P78543
Purity: ≥ 95%, as determined by HPLC.
Synonyms: MS4A1; CD20 Antigen; Prev. CD20; B-Lymphocyte Cell-Surface Antigen B1; Bp35; B-Lymphocyte Surface Antigen B1; FMC7; CD20 Receptor; B1; LEU-16; Membrane-Spanning 4-Domains, Subfamily A, Member 1; CVID5; Leukocyte Surface Antigen Leu-16; S7; B-Lymphocyte Antigen CD20; Membrane Spanning 4-Domains A1; Membrane-Spanning 4-Domains Subfamily A Member 1
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CD4 Protein, Human (HEK293, His)
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Cat. No.: HY-P70537
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD4; CD4 Receptor; CD4 Molecule; Surface Glycoprotein Variant; T-Cell Surface Glycoprotein CD4; CD4 Antigen; T-Cell Surface Antigen T4/Leu-3; CD4 Protein; Leu-3; CD4mut; T4; IMD79; CD4 Antigen (P55); OKT4D
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TROP-2 Protein, Human (HEK293, hFc)
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Cat. No.: HY-P72015
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TACSTD2; Epithelial Glycoprotein-1; Prev. M1S1; Membrane Component, Chromosome 1, Surface Marker 1; GA733-1; Gastrointestinal Tumor-Associated Antigen GA7331; TROP2; Pancreatic Carcinoma Marker Protein GA7331; Tumor-Associated Calcium Signal Transducer 2;
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CD19 Protein, Human (HEK293, His)
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Cat. No.: HY-P74330
Purity: ≥ 90%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: CD19; CDNA FLJ60916, Highly Similar To B-Lymphocyte Antigen CD19; CD19 Molecule; CDNA FLJ54955, Highly Similar To B-Lymphocyte Antigen CD19; B-Lymphocyte Surface Antigen B4; CD19 Antigen, Isoform CRA_f; T-Cell Surface Antigen Leu-12; CD19 Antigen, Isoform
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EGFR Protein, Human (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P78118
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: EGFR; Epidermal Growth Factor Receptor Variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell Growth Inhibiting Protein 40; ERRP; Receptor Protein-Tyrosine Kinase; Receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein E
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HER2/CD340 Protein, Human (S310Y, HEK293, His)
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Cat. No.: HY-P78680
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ERBB2; P185erbB2; Prev. NGL; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog); HER2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; NEU;
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Mucin-1/MUC1 Protein, Human (269a.a, HEK293, His)
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Cat. No.: HY-P78733
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MUC1; Mucin Short Variant E1; Prev. PUM; MUC1 Isoform SV7-LSP; Prev. MCKD1; MUC1 Isoform J18; KL-6; MUC1 Isoform J16; PEM; MUC1 Isoform J15; EMA; MUC1 Isoform J24; ADMCKD1; MUC1 Isoform T12; Mucin-1; MUC1 Isoform T13; ADMCKD; MUC1 Isoform M11; Ca15-3; MUC
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TROP-2 Protein, Human (187a.a, HEK293, His)
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Cat. No.: HY-P70728
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TACSTD2; Epithelial Glycoprotein-1; Prev. M1S1; Membrane Component, Chromosome 1, Surface Marker 1; GA733-1; Gastrointestinal Tumor-Associated Antigen GA7331; TROP2; Pancreatic Carcinoma Marker Protein GA7331; Tumor-Associated Calcium Signal Transducer 2;
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
Capetin (28-54), human
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- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
