1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. GSNOR


S-Nitrosoglutathione reductase (GSNOR) is a member of the alcohol dehydrogenase family (ADH) that regulates the levels of S-nitrosothiols (SNOs) through catabolism of S-nitrosoglutathione (GSNO).

GSNOR reduces the nitric oxide (NO) adduct S-nitrosoglutathione (GSNO), an essential reservoir for NO bioactivity. In plants, GSNOR has been found to be important in resistance to bacterial and fungal pathogens. GSNOR is ubiquitously expressed and catalyzes denitrosylation of GSNO, thereby downregulating protein S-nitrosylation in β-cells.

GSNOR activity appears to be necessary for normal development and fertility under optimal growth conditions.

GSNOR Related Products (1):

Cat. No. Product Name Effect Purity
  • HY-14984
    Inhibitor 99.89%
    N6022 is a potent, selective, reversible, and efficacious S-Nitrosoglutathione reductase(GSNOR) inhibitor with IC50 of 8 nM.
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