688347-51-5
688347-51-5
Chemical Structure
SPL-334
- CAS No.: 688347-51-5
- Formula:C22H15N3O3S2
- Molecular Weight:433.50
IUPAC Name: 4-((2-((2-cyanobenzyl)thio)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl)methyl)benzoic acid
InChIKey: UWWSCLNCHCROLL-UHFFFAOYSA-N
SMILES: N#CC1=C(CSC2=NC3=C(C(N2CC4=CC=C(C(O)=O)C=C4)=O)SC=C3)C=CC=C1
Biological Activity: SPL-334 is a potent and selective S-Nitrosoglutathione reductase (GSNOR) inhibitor. SPL-334 causes a significant reduction in the production of Th2 cytokines IL-5 and IL-13 and the levels of the chemokine CCL11 (eotaxin-1) in the airways. SPL-334 can be used in research of allergic airway inflammation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SPL-334 | 99.6% | SPL-334 is a potent and selective S-Nitrosoglutathione reductase (GSNOR) inhibitor. SPL-334 causes a significant reduction in the production of Th2 cytokines IL-5 and IL-13 and the levels of the chemokine CCL11 (eotaxin-1) in the airways. SPL-334 can be used in research of allergic airway inflammation. | ||||||||||||||||||||
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