2. Recombinant Proteins
  3. CD Antigens
  4. NK Cell CD Proteins
  5. CD253/TRAIL

CD253/TRAIL

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Cat. No. Product Name / Synonyms Species Source
  • HY-P7306
    TRAIL/TNFSF10 Protein, Human

    rHuTRAIL/Apo2L; TNFSF10; CD253

    		Human E. coli
    TRAIL Protein (TNFSF10), a member of the TNF superfamily, is a type II transmembrane protein. TRAIL Protein mainly interacts with TRAIL-R1 and TRAIL-R2, and induces apoptosis in tumor or infected cells. TRAIL Protein also binds with DR4, DR5, and OPG. TRAIL Protein can recruit FADD and further recruit and activates caspase-8 after binding to DR4 or DR5. Besides, TRAIL may also trigger nonapoptotic signaling through activating pro-inflammatory pathways. TRAIL protein is mainly expressed on surface of immune cells, such as cytotoxic T cells and natural killer (NK) cell. TRAIL/TNFSF10 Protein, Human is a recombinant human TRAIL (V114-G281) without any tag, which is expressed in E. coli.
  • HY-P7306AF
    Animal-Free TRAIL/TNFSF10 Protein, Human (His)

    TNFSF10; Apo2 Ligand; TL2; Apo2L; CD253

    		Human E. coli
    TRAIL/TNFSF10 protein is a cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly TNFRSF11B/OPG. It induces apoptosis, a process that can be mediated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG, which lack the ability to induce apoptosis. Animal-Free TRAIL/TNFSF10 Protein, Human (His) is the recombinant human-derived animal-FreeTRAIL/TNFSF10 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free TRAIL/TNFSF10 Protein, Human (His) is 168 a.a., with molecular weight of ~20.33 kDa.
  • HY-P77256
    TRAIL/TNFSF10 Protein, Rhesus Macaque

    Tumor Necrosis Factor Ligand Superfamily Member 10; Apo-2 Ligand; Apo-2L; TNF-Related Apoptosis-Inducing Ligand; Protein TRAIL; CD253; TNFSF10; APO2L; TRAIL

    		Rhesus Macaque E. coli
    TRAIL Protein (TNFSF10), a member of the TNF superfamily, is a type II transmembrane protein. TRAIL Protein mainly interacts with TRAIL-R1 and TRAIL-R2, and induces apoptosis in tumor or infected cells. TRAIL Protein also binds with DR4, DR5, and OPG. TRAIL Protein can recruit FADD and further recruit and activates caspase-8 after binding to DR4 or DR5. Besides, TRAIL may also trigger nonapoptotic signaling through activating pro-inflammatory pathways. TRAIL protein is mainly expressed on surface of immune cells, such as cytotoxic T cells and natural killer (NK) cell. TRAIL/TNFSF10 Protein, Rhesus Macaque is a recombinant Rhesus Macaque TRAIL (V114-G281) without any tag, which is expressed in E. coli.
  • HY-P7089AF
    Animal-Free TRAIL/TNFSF10 Protein, Mouse (His)

    rMuTRAIL/TNFSF10; TNF-related apoptosis-inducing ligand; Tumor necrosis factor ligand superfamily member 10

    		Mouse E. coli
    TRAIL/TNFSF10 protein binds to TNFRSF10A, TNFRSF10B, TNFRSF10C, TNFRSF10D, and possibly TNFRSF11B, inducing apoptosis. It can be modulated by decoy receptors TNFRSF10C, TNFRSF10D, and TNFRSF11B, which do not induce apoptosis. TRAIL/TNFSF10 exists as a homotrimer, interacting with its receptor monomers. This complex molecular interaction governs apoptotic signaling pathways. Animal-Free TRAIL/TNFSF10 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeTRAIL/TNFSF10 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free TRAIL/TNFSF10 Protein, Mouse (His) is 174 a.a., with molecular weight of ~21 kDa.
  • HY-P7306A
    TRAIL/TNFSF10 Protein, Human (N-His)

    rHuTRAIL/Apo2L; TNFSF10; CD253

    		Human E. coli
    TRAIL/TNFSF10 protein is a cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly TNFRSF11B/OPG. It induces apoptosis, a process that can be mediated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG, which lack the ability to induce apoptosis. TRAIL/TNFSF10 Protein, Human (N-His) is the recombinant human-derived TRAIL/TNFSF10 protein, expressed by E. coli , with N-6*His labeled tag. The total length of TRAIL/TNFSF10 Protein, Human (N-His) is 168 a.a., with molecular weight of ~22 kDa.
  • HY-P78528
    TRAIL/TNFSF10 Protein, Human (HEK293, His-Flag)

    Apo-2L; TRAIL; CD253; TNFSF10; Apo-2 ligand; APO2L; TL2

    		Human HEK293
    TRAIL Protein (TNFSF10), a member of the TNF superfamily, is a type II transmembrane protein. TRAIL Protein mainly interacts with TRAIL-R1 and TRAIL-R2, and induces apoptosis in tumor or infected cells. TRAIL Protein also binds with DR4, DR5, and OPG. TRAIL Protein can recruit FADD and further recruit and activates caspase-8 after binding to DR4 or DR5. Besides, TRAIL may also trigger nonapoptotic signaling through activating pro-inflammatory pathways. TRAIL protein is mainly expressed on surface of immune cells, such as cytotoxic T cells and natural killer (NK) cell. TRAIL/TNFSF10 Protein, Human (HEK293, His-Flag) is a recombinant human TRAIL (G118-G281) with N-terminal His and Flag tag, which is expressed in HEK293.
  • HY-P7089
    TRAIL/TNFSF10 Protein, Mouse (His,Solution)

    rMuTRAIL/TNFSF10; TNF-related apoptosis-inducing ligand; Tumor necrosis factor ligand superfamily member 10

    		Mouse E. coli
    TRAIL Protein (TNFSF10), a member of the TNF superfamily, is a type II transmembrane protein. TRAIL Protein mainly interacts with TRAIL-R1 and TRAIL-R2, and induces apoptosis in tumor or infected cells. TRAIL Protein also binds with DR4, DR5, and OPG. TRAIL Protein can recruit FADD and further recruit and activates caspase-8 after binding to DR4 or DR5. Besides, TRAIL may also trigger nonapoptotic signaling through activating pro-inflammatory pathways. TRAIL protein is mainly expressed on surface of immune cells, such as cytotoxic T cells and natural killer (NK) cell. TRAIL/TNFSF10 Protein, Mouse (His) is a recombinant mouse TRAIL (P118-N291) with N-terminal His tag, which is expressed in E.coli.
Cat. No. Product Name Effect Purity