2. Recombinant Proteins
  3. Enzymes & Regulators
  4. Serine/Threonine Kinase Proteins
  5. VRK Serine/Threonine Kinase 1

VRK Serine/Threonine Kinase 1

Recombinant Protein Expression Service

VRK Serine/Threonine Kinase 1

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Cat. No. Product Name / Synonyms Species Source
  • HY-P77504
    VRK1 Protein, Human (sf9)

    Serine/threonine-protein kinase VRK1; Vaccinia-related kinase 1; VRK1

    		Human Sf9 insect cells
    VRK1 Protein, a serine/threonine kinase, intricately regulates cell cycle, nuclear condensation, and transcription. It crucially induces Golgi disassembly during the cell cycle through PLK3 phosphorylation, impacting Golgi fragmentation. VRK1 modulates p53/TP53 by phosphorylating 'Thr-18', potentially hindering its interaction with MDM2. In response to DNA damage, VRK1 phosphorylates KAT5, enhancing histone acetyltransferase activity. VRK1 influences nuclear dynamics by phosphorylating BANF1, triggering its relocalization. Additionally, VRK1 targets ATF2, expanding its regulatory repertoire in transcriptional activity. VRK1 Protein, Human (sf9) is the recombinant human-derived VRK1 protein, expressed by Sf9 insect cells , with tag free. and with residual Gly-Pro in N-terminal (not related to functional changes) mutation. The total length of VRK1 Protein, Human (sf9) is 396 a.a., with molecular weight of ~47 kDa.
  • HY-P77505
    VRK1 Protein, Human (sf9, His-GST)

    Serine/threonine-protein kinase VRK1; Vaccinia-related kinase 1; VRK1

    		Human Sf9 insect cells
    The VRK1 protein is a serine/threonine kinase that complexly regulates the cell cycle, nuclear condensation, and transcription. It critically induces Golgi disassembly during the cell cycle via PLK3 phosphorylation, thereby affecting Golgi fragmentation. VRK1 Protein, Human (sf9, His-GST) is the recombinant human-derived VRK1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of VRK1 Protein, Human (sf9, His-GST) is 396 a.a., with molecular weight of 65-70 kDa.
Cat. No. Product Name Effect Purity