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  4. Epigenetics Compound Library Mini
Epigenetics Compound Library Mini

Cat. No.: HY-L005M

Epigenetics involves heritable phenotypic changes that occur without alterations to the underlying DNA sequence. Key mechanisms include DNA methylation, histone modifications, and regulation by small non-coding RNAs such as microRNAs. By modifying DNA, histones, or RNA—while leaving their primary sequences intact—these processes influence molecular function and regulation, thereby playing critical roles in cellular differentiation, embryonic development, gene expression control, aging, and diseases such as cancer.

MCE provide a unique collection of 297 epigenetics-related compounds. For each regulatory target and its subtype, 3 to 5 highly specific representative compounds have been retained, which can be used in epigenetic and related disease research.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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  • Biological Activity
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  • Composition

Description & Advantages

•   A unique collection of 297 small molecule modulators with biological activity used for epigenetics research and associated assays.

•   The library contains epigenetics-related compounds targeting HDAC, Histone Demethylase, Histone Acetyltransferase (HAT), DNA Methyltransferase (DNMT), Epigenetic Reader Domain, MicroRNA, etc.

•   A valuable tool for chemical genomics, epigenetic target identification in pharmacogenomics, and other biological applications.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   Rich documentation with structure, IC50, and other chemical & biological data.

•   NMR and HPLC validated to ensure the highest purity.

•   All compounds are in stock and continuously updated.

Product Details

Formulation:

A collection of 297 epigenetics related compounds supplied as pre-dissolved Solutions or Solid
Solution: 291 compounds supplied in 10 mM solution, 4 compounds supplied in 2 mM solution, 2 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

Composition

PARP (28)

PKC (25)

JAK (23)

HDAC (17)

AMPK (10)

STAT (6)

HIV (4)

HuR (4)

ROCK (4)

WDR5 (4)

CDK (3)

FLT3 (3)

FGFR (2)

MMP (2)

PKA (2)

Wnt (2)

Akt (1)

AP-1 (1)

CMV (1)

EGFR (1)

FOXO (1)

FXR (1)

GCGR (1)

HBV (1)

HPV (1)

HyT (1)

MARK (1)

mTOR (1)

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Compound Customization
  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
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Product Name:
Epigenetics Compound Library Mini
Cat. No.:
HY-L005M
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  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

Request for SDF File

Please fill out this form to request the SDF file. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Applicant Name *

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