Signaling Pathway Targeting Libraries
Cell signaling pathways are involved in the pathophysiology of many diseases. The mutations, molecular damage or functional change of the proteins in the signaling pathway will cause diseases. Knowledge of basic cell signaling mechanisms is therefore essential to understand pathophysiologic and pharmacologic mechanisms.
MCE can supply more than 30000 bioactive compounds, covering 500+ targets and 20+ hot signaling pathways, including GPCRs, Epigenetics, Immunology/Inflammations and cell proliferation, etc.
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Membrane Receptor-targeted Compound Library7,133 compoundsHY-L150
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Membrane Protein-targeted Compound Library7,999 compoundsHY-L149
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Coagulation and Anti-coagulation Compound Library1,525 compoundsHY-L136
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Osteogenesis Compound Library984 compoundsHY-L131
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Chemokine Compound Library257 compoundsHY-L132
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Nuclear Receptor Compound Library1,092 compoundsHY-L126
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5-HT Receptor Compound Library430 compoundsHY-L121
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GABA Receptor Compound Library206 compoundsHY-L120
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Potassium Channel Compound Library337 compoundsHY-L119
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Sodium Channel Blocker Library199 compoundsHY-L118
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Calcium Channel Blocker Library226 compoundsHY-L117
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Oxygen Sensing Compound Library4,317 compoundsHY-L045
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Wnt/Hedgehog/Notch Compound Library654 compoundsHY-L020
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TGF-beta/Smad Compound Library458 compoundsHY-L018
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Stem Cell Signaling Compound Library2,931 compoundsHY-L017
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Protein Tyrosine Kinase Compound Library1,695 compoundsHY-L016
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PI3K/Akt/mTOR Compound Library1,149 compoundsHY-L015
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NF-κB Signaling Compound Library1,801 compoundsHY-L014
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Transcription Factor-Targeted Library2,569 compoundsHY-L090
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Neuronal Signaling Compound Library3,961 compoundsHY-L013
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Membrane Transporter/Ion Channel Compound Library2,278 compoundsHY-L011
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MAPK Compound Library1,154 compoundsHY-L010
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Kinase Inhibitor Library3,998 compoundsHY-L009
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Phosphatase Inhibitor Library185 compoundsHY-L081
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JAK/STAT Compound Library738 compoundsHY-L008
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Immunology/Inflammation Compound Library8,643 compoundsHY-L007
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Histone Modification Research Compound Library931 compoundsHY-L024
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Protein-protein Interaction Inhibitor Library826 compoundsHY-L109
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GPCR/G Protein Compound Library3,519 compoundsHY-L006
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Epigenetics Compound Library2,031 compoundsHY-L005
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Cell Cycle/DNA Damage Compound Library3,522 compoundsHY-L004
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Ubiquitination Compound Library507 compoundsHY-L050
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Reprogramming Compound Library3,231 compoundsHY-L039
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Differentiation Inducing Compound Library2,574 compoundsHY-L038
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Antioxidant Compound Library2,489 compoundsHY-L037
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Neurotransmitter Receptor Compound Library2,593 compoundsHY-L062
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Cytoskeleton Compound Library2,313 compoundsHY-L060
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Angiogenesis-Related Compound Library3,660 compoundsHY-L088
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Mitochondria-Targeted Compound Library1,182 compoundsHY-L089
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Endoplasmic Reticulum Stress Compound Library379 compoundsHY-L054
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Exosomes Compound Library58 compoundsHY-L072
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Mechanoreceptors Compound Library391 compoundsHY-L095
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TCA Cycle Compound Library72 compoundsHY-L148
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Cuproptosis Compound Library446 compoundsHY-L133
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Metabolism/Protease Compound Library7,360 compoundsHY-L012
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Glycolysis Compound Library1,379 compoundsHY-L058
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Autophagy Compound Library2,080 compoundsHY-L029
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Apoptosis Compound Library3,650 compoundsHY-L003
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Ferroptosis Compound Library1,255 compoundsHY-L051
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Glucose Metabolism Compound Library1,777 compoundsHY-L092
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Lipid Metabolism Compound Library1,026 compoundsHY-L091
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Glutamine Metabolism Compound Library1,827 compoundsHY-L064
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Pyroptosis Compound Library2,034 compoundsHY-L059
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Anti-Cancer Metabolism Compound Library3,806 compoundsHY-L083
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Epigenetics Compound Library Mini295 compoundsHY-L005M
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Cytokine Inhibitors Library1,416 compoundsHY-L161
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Lactic Acid Metabolite Compound Library61 compoundsHY-L250
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Mitophagy Compound Library655 compoundsHY-L180
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Ion Channel Compound Library1,751 compoundsHY-L166
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Energy Metabolites Library89 compoundsHY-L263
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Serine/Threonine Kinase Inhibitor Library2,276 compoundsHY-L164
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Dopamine Receptor Compound Library282 compoundsHY-L165
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Extracellular Vesicles (EVs) Compound Library707 compoundsHY-L168
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High-Efficiency Gene Editing Compound Library761 compoundsHY-L244
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Cell Death Inhibitor Library Mini23 compoundsHY-L162M
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RNA Binding Bioactive Compound Library858 compoundsHY-L248
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Cell Proliferation Compound Library3,628 compoundsHY-L201
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Metabolic Enzyme Compound Library4,407 compoundsHY-L146
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Lactylation Compound Library6,182 compoundsHY-L249
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Mitochondrial Protection Compound Library1,112 compoundsHY-L144
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Protease Inhibitor Library956 compoundsHY-L147
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Kinase Inhibitor Library Mini270 compoundsHY-L009M
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KRAS Targeted Compound Library82 compoundsHY-L260
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Mitochondrial Toxicity Compound Library545 compoundsHY-L155