1. Recombinant Proteins
  2. Receptor Proteins
  3. Siglec
  4. Siglec-10
Cat. No. Product Name / Synonyms Species Source
  • HY-P72411
    Siglec-10 Protein, Human (Biotinylated, HEK293, Fc-Avi)

    MGC126774; PRO940; Siglec10; SLG2; sialic acid-binding Ig-like lectin 10; siglec-like gene 2

    Human HEK293
    Siglec-10 Protein, identified as a putative adhesion molecule, mediates sialic-acid dependent cellular binding, preferring alpha-2,3- or alpha-2,6-linked sialic acid. Its sialic acid recognition site may undergo masking through cis interactions. In immune responses, Siglec-10 acts as an inhibitory receptor, inducing ligand-induced tyrosine phosphorylation, recruiting SH2 domain-containing phosphatases, and negatively regulating B-cell antigen receptor signaling via PTPN6/SHP-1. In collaboration with CD24, it selectively suppresses the immune response to DAMPs, regulates NK cell response, controls autoimmunity, and inhibits cross-presentation during adaptive immune responses by CD8-alpha(+) dendritic cells. Siglec-10 interacts with proteins including PTPN6/SHP-1, NCF1, CD24, HMGB1, RIGI, CBL, and PTPN11. Siglec-10 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived Siglec-10 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag. The total length of Siglec-10 Protein, Human (Biotinylated, HEK293, Fc-Avi) is 530 a.a., with molecular weight of 100-130 kDa.
  • HY-P78206
    Siglec-10 Protein, Human (Biotinylated, R119A, HEK293, His-Avi)

    SLG2; SIGLEC10; MGC126774; PRO940

    Human HEK293
    Siglec-10 Protein, identified as a putative adhesion molecule, mediates sialic-acid dependent cellular binding, preferring alpha-2,3- or alpha-2,6-linked sialic acid. Its sialic acid recognition site may undergo masking through cis interactions. In immune responses, Siglec-10 acts as an inhibitory receptor, inducing ligand-induced tyrosine phosphorylation, recruiting SH2 domain-containing phosphatases, and negatively regulating B-cell antigen receptor signaling via PTPN6/SHP-1. In collaboration with CD24, it selectively suppresses the immune response to DAMPs, regulates NK cell response, controls autoimmunity, and inhibits cross-presentation during adaptive immune responses by CD8-alpha(+) dendritic cells. Siglec-10 interacts with proteins including PTPN6/SHP-1, NCF1, CD24, HMGB1, RIGI, CBL, and PTPN11. Siglec-10 Protein, Human (Biotinylated, R119A, HEK293, His-Avi) is the recombinant human-derived Siglec-10 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Siglec-10 Protein, Human (Biotinylated, R119A, HEK293, His-Avi) is 530 a.a., with molecular weight of 68-80 kDa.
  • HY-P78514
    Siglec-10 Protein, Human (R119A, HEK293, His-Avi)

    SLG2; SIGLEC10; MGC126774; PRO940

    Human HEK293
    Siglec-10 protein is thought to be a putative adhesion molecule that mediates sialic acid-dependent cell binding, preferentially selecting α-2,3- or α-2,6-linked sialic acid. Its sialic acid recognition site may be masked by cis interactions. Siglec-10 Protein, Human (R119A, HEK293, His-Avi) is the recombinant human-derived Siglec-10 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Siglec-10 Protein, Human (R119A, HEK293, His-Avi) is 530 a.a., with molecular weight of 70-90 kDa.
  • HY-P72476
    Siglec-10 Protein, Human (HEK293, Fc)

    Sialic acid-binding Ig-like lectin 10; Siglec-10; SIGLEC10; SLG2

    Human HEK293
    Siglec-10 protein is thought to be a putative adhesion molecule that mediates sialic acid-dependent cell binding, preferentially selecting α-2,3- or α-2,6-linked sialic acid. Its sialic acid recognition site may be masked by cis interactions. Siglec-10 Protein, Human (HEK293, Fc) is the recombinant human-derived Siglec-10 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Siglec-10 Protein, Human (HEK293, Fc) is 530 a.a., with molecular weight of 110-130 kDa.
  • HY-P76642
    Siglec-10 Protein, Human (HEK293, His)

    Sialic acid-binding Ig-like lectin 10; Siglec-10; SIGLEC10; SLG2

    Human HEK293
    Siglec-10 protein is thought to be a putative adhesion molecule that mediates sialic acid-dependent cell binding, preferentially selecting α-2,3- or α-2,6-linked sialic acid. Its sialic acid recognition site may be masked by cis interactions. Siglec-10 Protein, Human (HEK293, His) is the recombinant human-derived Siglec-10 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-10 Protein, Human (HEK293, His) is 534 a.a., with molecular weight of ~59.5 kDa.
  • HY-P70448
    Siglec-10 Protein, Mouse (HEK293, Fc)

    SIGLEC10; SiglecG; Siglec-G; MGC126774; PRO940; Siglec10; SLG2; sialic acid-binding Ig-like lectin 10; Siglec-10; siglec-like gene 2; Siglec-like protein 2; SLG2sialic acid binding Ig-like lectin 10 Ig-like lectin 7

    Mouse HEK293
    Siglec-10 protein is an adhesion molecule that mediates sialic acid-dependent cell binding, preferentially selecting α-2,3- or α-2,6-linked sialic acid. Its sialic acid recognition site may be masked through cis interactions. Siglec-10 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Siglec-10 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Siglec-10 Protein, Mouse (HEK293, Fc) is 525 a.a., with molecular weight of 110-135 kDa.
  • HY-P78205
    Siglec-10 Protein, Human (Biotinylated, HEK293, His-Avi)

    SLG2; SIGLEC10; MGC126774; PRO940

    Human HEK293
    Siglec-10 protein is thought to be a putative adhesion molecule that mediates sialic acid-dependent cell binding, preferentially selecting α-2,3- or α-2,6-linked sialic acid. Its sialic acid recognition site may be masked by cis interactions. Siglec-10 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Siglec-10 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Siglec-10 Protein, Human (Biotinylated, HEK293, His-Avi) is 530 a.a., with molecular weight of 70-80 kDa.
  • HY-P78516
    Siglec-10 Protein, Human (HEK293, Fc-Avi)

    SLG2; SIGLEC10; MGC126774; PRO940

    Human HEK293
    Siglec-10 Protein, identified as a putative adhesion molecule, mediates sialic-acid dependent cellular binding, preferring alpha-2,3- or alpha-2,6-linked sialic acid. Its sialic acid recognition site may undergo masking through cis interactions. In immune responses, Siglec-10 acts as an inhibitory receptor, inducing ligand-induced tyrosine phosphorylation, recruiting SH2 domain-containing phosphatases, and negatively regulating B-cell antigen receptor signaling via PTPN6/SHP-1. In collaboration with CD24, it selectively suppresses the immune response to DAMPs, regulates NK cell response, controls autoimmunity, and inhibits cross-presentation during adaptive immune responses by CD8-alpha(+) dendritic cells. Siglec-10 interacts with proteins including PTPN6/SHP-1, NCF1, CD24, HMGB1, RIGI, CBL, and PTPN11. Siglec-10 Protein, Human (HEK293, Fc-Avi) is the recombinant human-derived Siglec-10 protein, expressed by HEK293, with C-Avi, C-hFc labeled tag. The total length of Siglec-10 Protein, Human (HEK293, Fc-Avi) is 530 a.a., with molecular weight of 95-110 kDa.
  • HY-P701304
    PE-Labeled Siglec-10 Protein, Human (HEK293, His)

    SIGLEC10; MGC126774; PRO940; Siglec10; SLG2

    Human HEK293
    Siglec-10 Protein, identified as a putative adhesion molecule, mediates sialic-acid dependent cellular binding, preferring alpha-2,3- or alpha-2,6-linked sialic acid. Its sialic acid recognition site may undergo masking through cis interactions. In immune responses, Siglec-10 acts as an inhibitory receptor, inducing ligand-induced tyrosine phosphorylation, recruiting SH2 domain-containing phosphatases, and negatively regulating B-cell antigen receptor signaling via PTPN6/SHP-1. In collaboration with CD24, it selectively suppresses the immune response to DAMPs, regulates NK cell response, controls autoimmunity, and inhibits cross-presentation during adaptive immune responses by CD8-alpha(+) dendritic cells. Siglec-10 interacts with proteins including PTPN6/SHP-1, NCF1, CD24, HMGB1, RIGI, CBL, and PTPN11. PE-Labeled Siglec-10 Protein, Human (HEK293, His) is the recombinant human-derived PE-Labeled Siglec-10 protein, expressed by HEK293, with His labeled tag. The total length of PE-Labeled Siglec-10 Protein, Human (HEK293, His) is 530 a.a., with molecular weight of 61.8 kDa.
  • HY-P701083
    Siglec-10 Protein, Cynomolgus (HEK293, His, solution)

    SLG2; SIGLEC10; MGC126774; PRO940

    Cynomolgus HEK293
    Siglec-10 protein is thought to be a putative adhesion molecule that mediates sialic acid-dependent cell binding, preferentially selecting α-2,3- or α-2,6-linked sialic acid. Its sialic acid recognition site may be masked by cis interactions. Siglec-10 Protein, Cynomolgus (HEK293, His, solution) is the recombinant cynomolgus-derived Siglec-10 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-10 Protein, Cynomolgus (HEK293, His, solution) is 536 a.a., with molecular weight of 70-80 kDa.
Cat. No. Product Name Effect Purity