1. Recombinant Proteins
  2. CD Antigens
  3. T Cell CD Proteins
  4. CD3E-CD3G Heterodimer Proteins

CD3E-CD3G Heterodimer Proteins

Cat. No. Product Name / Synonyms Species Source
  • HY-P77605
    CD3E-CD3G Heterodimer Protein, Cynomolgus (HEK293, Fc)

    CD3; CD3G; CD3g; T3G; CD3e; CD3E; CD3 epsilon&CD3 gamma; CD3E&CD3G

    Cynomolgus HEK293
    CD3E/CD3 epsilon 1-27 peptide, crucial in the TCR-CD3 complex, transmits signals during T-cell activation. As APCs activate the TCR, CD3E, with ITAMs, undergoes LCK/FYN-mediated phosphorylation, initiating downstream signaling. Beyond signaling, CD3E contributes to T-cell development, forming CD3D/CD3E and CD3G/CD3E heterodimers. It regulates TCR-CD3 internalization through endocytosis sequences and interacts with CD6, NCK1, and NUMB, essential for internalization and degradation. The TCR-CD3 complex, including CD3D/CD3E and CD3G/CD3E heterodimers and CD3Z homodimers, demonstrates versatility in TCR assembly, allowing substitution of TCRalpha and TCRbeta with TCRgamma and TCRdelta. CD3E-CD3G Heterodimer Protein, Cynomolgus (HEK293, Fc) is a recombinant protein dimer complex containing cynomolgus-derived CD3E-CD3G Heterodimer protein, expressed by HEK293, with C-hFc labeled tag. CD3E-CD3G Heterodimer Protein, Cynomolgus (HEK293, Fc), has molecular weight of 36.9 kDa(CD3E) & 36.5 kDa(CD3G), respectively.
  • HY-P77609
    CD3E-CD3G Heterodimer Protein, Human (HEK293, His)

    CD3; CD3G; CD3g; T3G; CD3e; CD3E; CD3 epsilon&CD3 gamma; CD3E&CD3G

    Human HEK293
    CD3 epsilon, a crucial part of the TCR-CD3 complex on T-lymphocytes, facilitates TCR-mediated signal transmission. When APCs activate TCR, CD3 epsilon, with CD3D, CD3G, and CD3Z, relays signals across the cell membrane via ITAMs. LCK and FYN phosphorylate CD3 epsilon upon TCR engagement, initiating downstream signaling. Essential for T-cell development, CD3 epsilon forms heterodimers, initiating TCR-CD3 complex assembly. It's vital for TCR-CD3 complex internalization and down-regulation, interacting with CD6, NCK1, and NUMB, underscoring its pivotal role in T-cell processes. CD3E-CD3G Heterodimer Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived CD3E-CD3G Heterodimer protein, expressed by HEK293, with C-His labeled tag. CD3E-CD3G Heterodimer Protein, Human (HEK293, His), has molecular weight of 25-40 kDa.
  • HY-P75414
    CD3E-CD3G Heterodimer Protein, Mouse (HEK293, Fc)

    AI504783 Protein; CD3 Protein; CD3epsilon Protein; T3e Protein

    Mouse HEK293
    The CD3E protein, with predicted functions like SH3 domain binding and protein heterodimerization, plays a crucial role in nervous system development and cell adhesion. It is involved in T cell activation, cytokine production, and signal transduction. Located in various cellular components, its expression is observed in the colon and hemolymphoid system. CD3E, the human ortholog, has implications in immunodeficiency 18, emphasizing its role in immune system functionality. Biased expression occurs in the thymus and spleen, highlighting its importance in immune processes. CD3E-CD3G Heterodimer Protein, Mouse (HEK293, Fc) is a recombinant protein dimer complex containing mouse-derived CD3E-CD3G Heterodimer protein, expressed by HEK293, with C-hFc labeled tag. CD3E-CD3G Heterodimer Protein, Mouse (HEK293, Fc), has molecular weight of ~38-40 kDa.
  • HY-P77611
    CD3E-CD3G Heterodimer Protein, Human (HEK293, Fc)

    CD3; CD3G; CD3g; T3G; CD3e; CD3E; CD3 epsilon&CD3 gamma; CD3E&CD3G

    Human HEK293
    CD3 epsilon, a crucial part of the TCR-CD3 complex on T-lymphocytes, facilitates TCR-mediated signal transmission. When APCs activate TCR, CD3 epsilon, with CD3D, CD3G, and CD3Z, relays signals across the cell membrane via ITAMs. LCK and FYN phosphorylate CD3 epsilon upon TCR engagement, initiating downstream signaling. Essential for T-cell development, CD3 epsilon forms heterodimers, initiating TCR-CD3 complex assembly. It's vital for TCR-CD3 complex internalization and down-regulation, interacting with CD6, NCK1, and NUMB, underscoring its pivotal role in T-cell processes. CD3E-CD3G Heterodimer Protein, Human (HEK293, Fc) is a recombinant protein dimer complex containing human-derived CD3E-CD3G Heterodimer protein, expressed by HEK293, with C-hFc labeled tag. CD3E-CD3G Heterodimer Protein, Human (HEK293, Fc), has molecular weight of 40-60 kDa.
  • HY-P77613
    CD3E-CD3G Heterodimer Protein, Human (Biotinylated, HEK293, Fc-Avi)

    CD3; CD3G; CD3g; T3G; CD3e; CD3E; CD3 epsilon&CD3 gamma; CD3E&CD3G

    Human HEK293
    CD3 epsilon, a crucial part of the TCR-CD3 complex on T-lymphocytes, facilitates TCR-mediated signal transmission. When APCs activate TCR, CD3 epsilon, with CD3D, CD3G, and CD3Z, relays signals across the cell membrane via ITAMs. LCK and FYN phosphorylate CD3 epsilon upon TCR engagement, initiating downstream signaling. Essential for T-cell development, CD3 epsilon forms heterodimers, initiating TCR-CD3 complex assembly. It's vital for TCR-CD3 complex internalization and down-regulation, interacting with CD6, NCK1, and NUMB, underscoring its pivotal role in T-cell processes. CD3E-CD3G Heterodimer Protein, Human (Biotinylated, HEK293, Fc-Avi) is a recombinant protein dimer complex containing human-derived CD3E-CD3G Heterodimer protein, expressed by HEK293, with C-Avi, C-hFc labeled tag. CD3E-CD3G Heterodimer Protein, Human (Biotinylated, HEK293, Fc-Avi), has molecular weight of 48-55 kDa.
  • HY-P700678
    CD3E-CD3G Heterodimer Protein, Human (Biotinylated, HEK293, His)

    CD3; CD3G; CD3g; T3G; CD3e; CD3E; CD3 epsilon&CD3 gamma; CD3E&CD3G

    Human HEK293
    CD3 epsilon, a crucial part of the TCR-CD3 complex on T-lymphocytes, facilitates TCR-mediated signal transmission. When APCs activate TCR, CD3 epsilon, with CD3D, CD3G, and CD3Z, relays signals across the cell membrane via ITAMs. LCK and FYN phosphorylate CD3 epsilon upon TCR engagement, initiating downstream signaling. Essential for T-cell development, CD3 epsilon forms heterodimers, initiating TCR-CD3 complex assembly. It's vital for TCR-CD3 complex internalization and down-regulation, interacting with CD6, NCK1, and NUMB, underscoring its pivotal role in T-cell processes. CD3E-CD3G Heterodimer Protein, Human (Biotinylated, HEK293, His) is a recombinant protein dimer complex containing human-derived CD3E-CD3G Heterodimer protein, expressed by HEK293, with C-His labeled tag. CD3E-CD3G Heterodimer Protein, Human (Biotinylated, HEK293, His), has molecular weight of 25-40 kDa.
  • HY-P76237
    CD3E-CD3G Heterodimer Protein, Rhesus Macaque (HEK293, Fc)

    CD3E & CD3G; CD3 epsilon & CD3 gamma; CD3 epsilon/gamma

    Rhesus Macaque HEK293
    CD3E protein has predicted functions such as SH3 domain binding and protein heterodimerization, and plays a crucial role in nervous system development and cell adhesion. It is involved in T cell activation, cytokine production and signal transduction. CD3E-CD3G Heterodimer Protein, Rhesus Macaque (HEK293, Fc) is a recombinant protein dimer complex containing Rhesus Macaque-derived CD3E-CD3G Heterodimer protein, expressed by HEK293 , with C-hFc labeled tag. CD3E-CD3G Heterodimer Protein, Rhesus Macaque (HEK293, Fc), has molecular weight of ~75.4 (37.9+37.5) KDa.
  • HY-P77606
    CD3E-CD3G Heterodimer Protein, Cynomolgus (Biotinylated, HEK293, Fc)

    CD3; CD3G; CD3g; T3G; CD3e; CD3E; CD3 epsilon&CD3 gamma; CD3E&CD3G

    Cynomolgus HEK293
    CD3E/CD3 epsilon 1-27 peptide, crucial in the TCR-CD3 complex, transmits signals during T-cell activation. As APCs activate the TCR, CD3E, with ITAMs, undergoes LCK/FYN-mediated phosphorylation, initiating downstream signaling. Beyond signaling, CD3E contributes to T-cell development, forming CD3D/CD3E and CD3G/CD3E heterodimers. It regulates TCR-CD3 internalization through endocytosis sequences and interacts with CD6, NCK1, and NUMB, essential for internalization and degradation. The TCR-CD3 complex, including CD3D/CD3E and CD3G/CD3E heterodimers and CD3Z homodimers, demonstrates versatility in TCR assembly, allowing substitution of TCRalpha and TCRbeta with TCRgamma and TCRdelta. CD3E-CD3G Heterodimer Protein, Cynomolgus (Biotinylated, HEK293, Fc) is a recombinant protein dimer complex containing cynomolgus-derived CD3E-CD3G Heterodimer protein, expressed by HEK293, with C-hFc labeled tag. CD3E-CD3G Heterodimer Protein, Cynomolgus (Biotinylated, HEK293, Fc), has molecular weight of 44-46 kDa.
Cat. No. Product Name Effect Purity