1. Natural Products
  2. Stilbenes

Stilbenes

Stilbenes are an important group of non-flavonoid phytochemicals of polyphenolic structure characterized by the presence of a 1, 2-diphenylethylene nucleus and are structurally divided into two categories, the monomeric and oligomeric stilbenes. They are widely found in mosses and higher plants. These compounds and their derivatives are of significant interest for drug research and development because of their potential in therapeutic or preventive applications, exemplified by Resveratrol and Combretastatin A4. These compounds can be potent anti-cancer agents.

Stilbenes (42):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0828
    Pterostilbene 537-42-8 99.83%
    Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties. Pterostilbene blocks ROS production, also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide.
    Pterostilbene
  • HY-N0318
    Salvianolic acid A 96574-01-5 99.72%
    Salvianolic acid A could protect the blood brain barrier through matrix metallopeptidase 9 (MMP-9) inhibition and anti-inflammation.
    Salvianolic acid A
  • HY-13518
    Piceatannol 10083-24-6 98.90%
    Piceatannol is a well-known Syk inhibitor and reduces the expression of iNOS induced by TNF. Piceatannol is an effective agent for research of acute lung injury (ALI). Piceatannol is a naturally occurring polyphenolic stilbene found in various fruits and vegetables and exhibits anticancer and anti-inflammatory properties. Piceatannol induces apoptosis in DLBCL cell lines. Piceatannol induces autophagy and apoptosis in MOLT-4 human leukemia cells.
    Piceatannol
  • HY-N2146
    Combretastatin A4 117048-59-6 99.76%
    Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.
    Combretastatin A4
  • HY-N0619
    Mulberroside A 102841-42-9 99.86%
    Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.). Mulberroside A decreases the expressions of TNF-α, IL-1β, and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and the phosphorylation of ERK, JNK, and p38, exhibiting anti-inflammatory antiapoptotic effects. Mulberroside A shows inhibitory activity against mushroom tyrosinase with an IC50 of 53.6 μM.
    Mulberroside A
  • HY-N1134
    (-)-Hinokiresinol 17676-24-3
    (-)-Hinokiresinol (Hinokiresinol; trans-Hinokiresinol) can be isolated from Chamaecyparis obtusa. (-)-Hinokiresinol has weak termiticidal activity but strong antifeedant and repellent activity.
    (-)-Hinokiresinol
  • HY-N0671R
    Rhapontin (Standard) 155-58-8
    Rhapontin (Standard) is the analytical standard of Rhapontin. This product is intended for research and analytical applications. Rhapontin (Rhaponiticin), a component of rhubarb (Rheum officinale Baill), induces apoptosis resulting in suppression of proliferation of human stomach cancer KATO III cells.
    Rhapontin (Standard)
  • HY-17449
    Fosbretabulin disodium 168555-66-6 99.47%
    Fosbretabulin disodium (CA 4DP) is a tubulin destabilizing agent. Fosbretabulin disodium is the Combretastatin A4 proagent that selectively targets endothelial cells, induces regression of nascent tumour neovessels, reduces tumour blood flow and causes central tumour necrosis.
    Fosbretabulin disodium
  • HY-N0652
    2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside 82373-94-2 99.20%
    2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside isolats from the roots of Polygonaceae species, inhibits the formation of 5-HETE, HHT and thromboxane B2. 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside has hypotensive, anti-ageing, anti-inflammatory, hypolipidemic, cardioprotective, and neuroprotective actions.
    2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside
  • HY-N2593
    Isorhapontigenin 32507-66-7 99.82%
    Isorhapontigenin, an orally bioavailable dietary polyphenol isolated from the Chinese herb Gnetum cleistostachyum, displays anti-inflammatory effects. Isorhapontigenin induces autophagy and inhibits invasive bladder cancer formation.
    Isorhapontigenin
  • HY-N0671
    Rhapontin 155-58-8 99.25%
    Rhapontin (Rhaponiticin), a component of rhubarb (Rheum officinale Baill), induces apoptosis resulting in suppression of proliferation of human stomach cancer KATO III cells.
    Rhapontin
  • HY-N2485
    4'-Methoxyresveratrol 33626-08-3 99.48%
    4'-Methoxyresveratrol (4'-O-Methylresveratrol) is a polyphenol derived from Dipterocarpaceae, with antiandrogenic, antifungal and anti-inflammatory activities. 4'-Methoxyresveratrol alleviates AGE-induced inflammation through suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation.
    4'-Methoxyresveratrol
  • HY-N6002
    3'-Hydroxypterostilbene 475231-21-1 99.46%
    3'-Hydroxypterostilbene is a Pterostilbene (HY-N0828) analogue. 3'-Hydroxypterostilbene inhibits the growth of COLO 205, HCT-116 and HT-29 cells with IC50s of 9.0, 40.2 and 70.9 µM, respectively. 3'-Hydroxypterostilbene significantly down-regulates PI3K/Akt and MAPKs signaling pathways and effectively inhibits the growth of human colon cancer cells by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene can be used for the research of cancer.
    3'-Hydroxypterostilbene
  • HY-N2486
    Desoxyrhaponticin 30197-14-9 99.80%
    Desoxyrhaponticin is a kind of oral drug that inhibits effective fatty acid synthesis (FASN), and has a fatal effect on cancer cells. Desoxyrhaponticin has the ability to inhibit glucose uptake, improve oral glucose tolerance as a diabetic agent, and possess anti-diabetic effects.
    Desoxyrhaponticin
  • HY-N0120
    (E/Z)-Polydatin 65914-17-2 98.44%
    (E/Z)-Polydatin ((E/Z)-Piceid) is a monocrystalline compound originally isolated from the root and rhizome of Polygonum cuspidatum. (E/Z)-Polydatin has anti-platelet aggregation, anti-oxidative action of low-density lipoprotein (LDL), cardioprotective activity, anti-inflammatory and immune-regulating functions.
    (E/Z)-Polydatin
  • HY-N5027
    Oxyberberine 549-21-3 99.85%
    Oxyberberine (Oxyberberin) is a natural alkaloid isolated from many plants.
    Oxyberberine
  • HY-N2387
    Pinosylvin 22139-77-1 99.94%
    Pinosylvin is a pre-infectious stilbenoid toxin isolated from the heartwood of Pinus species, has anti-bacterial activities. Pinosylvin is a resveratrol analogue, can induce cell apoptosis and autophapy in leukemia cells.
    Pinosylvin
  • HY-126052
    Gnetol 86361-55-9 99.86%
    Gnetol is a phenolic compound isolated from the root of Gnetum montanum . Gnetol potently inhibits COX-1 (IC50 of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC50 of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities.
    Gnetol
  • HY-N3059
    Pinostilbene 42438-89-1 98.00%
    Pinostilbene (trans-Pinostilbene) is a major metabolite of Pterostilbene. Pinostilbene exhibits inhibitory effects on colon cancer cells.
    Pinostilbene
  • HY-N4093
    Astringin 29884-49-9 98.30%
    Astringin (trans-Astringin) is a natural glycoside found in the bark of Picea sitchensis and Picea abies (Norway spruce), in Vitis vinifera cell cultures and in wine. Astringin has potent antioxidant capacity and cancer-chemopreventive activity.
    Astringin