1. Protein Tyrosine Kinase/RTK
    Autophagy
  2. Syk
    Autophagy

Piceatannol (Synonyms: Astringenin; trans-Piceatannol)

Cat. No.: HY-13518 Purity: 99.49%
Handling Instructions

Piceatannol is a selective inhibitor of protein tyrosine kinase Syk.

For research use only. We do not sell to patients.
Piceatannol Chemical Structure

Piceatannol Chemical Structure

CAS No. : 10083-24-6

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 87 In-stock
10 mg USD 79 In-stock
25 mg USD 156 In-stock
50 mg USD 228 In-stock
100 mg USD 324 In-stock
200 mg   Get quote  
500 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Piceatannol is a selective inhibitor of protein tyrosine kinase Syk. It could inhibit ICa,L, Ito, IKr, Ca2+ transients and Na+-Ca2+ exchange except IK1. Shows multiple biological activities such as anti-inflammatory, antiproliferative and immunomodulatory effects. In vitro: The treatment of human myeloid cells with piceatannol suppressed TNF-induced DNA binding activity of NF-κB. The effect of piceatannol was not restricted to myeloid cells, as TNF-induced NF-κB activation was also suppressed in lymphocyte and epithelial cells. Piceatannol also inhibited NF-κB activated by H2O2, PMA, LPS, okadaic acid, and ceramide. [1]

References
Molecular Weight

244.24

Formula

C₁₄H₁₂O₄

CAS No.

10083-24-6

SMILES

OC1=CC=C(/C=C/C2=CC(O)=CC(O)=C2)C=C1O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 31 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Piceatannol
Cat. No.:
HY-13518
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