1. Screening Libraries
  2. Metabolism/Protease Compound Library

Metabolism/Protease Compound Library

Cat. No.: HY-L012
Library Contents: XLSX PDF SDF

Metabolism is the set of life-sustaining chemical reactions in organisms. Metabolic pathways are enzyme-mediated biochemical reactions that lead to biosynthesis (anabolism) or breakdown (catabolism) of natural product small molecules within a cell or tissue. Acting as catalysts, enzymes are crucial to metabolism - they allow a reaction to proceed more rapidly - and they also allow the regulation of the rate of a metabolic reaction. Proteases are used throughout an organism for various metabolic processes. Proteases control a great variety of physiological processes that are critical for life, including the immune response, cell cycle, cell death, wound healing, food digestion, and protein and organelle recycling. Imbalances in metabolic activities have been found to be critical in a number of pathologies, such as cardiovascular diseases, inflammation, cancer, and neurodegenerative diseases.

MCE designs a unique collection of 2018 Metabolism/Protease-related small molecules that act as a useful tool for drug discovery of metabolism-related diseases.

MCE Metabolism/Protease Compound Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 1980 compounds supplied in 10 mM solution, 31 compounds supplied in 2 mM solution and 7 compounds supplied in 3 mg/mL solution.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

Get quote In-stock
50 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

Get quote In-stock
100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

Get quote In-stock
2 × 100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

Get quote In-stock

Please contact us at

[email protected]

Top Publications Citing Use of Products
  • Description

  • Product Details

  • Composition

  • Documentation

Description
& Advantages

•   A unique collection of 2018 Metabolism/Protease-related small molecules for high throughput screening (HTS) and high content screening (HCS).

•   Targets such as PDE, Cytochrome P450, HMG-CoA Reductase, DPP4, Proteasome, HCV Protease, IDO, Cathepsin, MMP, etc.

•   A useful tool for drug discovery of metabolism-related diseases.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some inhibitors have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 2018 Metabolism/Protease related compounds supplied as pre-dissolved Solutions or Solid
Solution: 1980 compounds supplied in 10 mM solution, 31 compounds supplied in 2 mM solution, 7 compounds supplied in 3 mg/mL solution.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

Metabolism/Protease Compound Library

Source: MedChem Express

Documentation

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Container *

    Remarks

    Inquiry Online

    Inquiry Information

    Product Name:
    Metabolism/Protease Compound Library
    Cat. No.:
    HY-L012
    Quantity:
    MCE Japan Authorized Agent:

    Request SDF File

    Please enter your email address. We will send your requested SDF file to you as soon as possible.

    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack