1. Screening Libraries
  2. Cell-based Compound Screening

Cell-based Compound Screening

120+ tumor cell lines Multi-method detection Professional screening team

Compound activity screening is not only the starting point of new drug development, but also a decisive step in new drug discovery. Through compound activity screening, people can test and obtain compounds with specific physiological activities. The MedChemExpress (MCE) compound activity screening platform takes the whole cell as the research object, and can provide a variety of cell proliferation and cytotoxicity detection services such as CCK-8 method, colony formation method, and can detect the effect of compounds on cell apoptosis, cell cycle, signal effects such as transduction, obtains a large amount of relevant information from a single experiment, determines the biological activity and potential toxicity of the compound.

Screen process

Advantages

More than 120 human tumor cell lines are available in our cell-based compound screening platform. We offer potency testing of new drugs on cell proliferation and viability with a variety of assay formats including MTT, CCK8, and clonogenic assay. Cell apoptosis, cell cycle, cell signal transduction can also be detected in our platform.

  • 120+ tumor cell lines
  • A variety of cell viability assays
  • Cell imaging
  • Professional compound screening team
  • Customization high cost-effective service
  • Advanced equipment

Human tumor cell lines

Tumor Cell Line Name
Thyroid cancer SW579, TT, KMH-2
Esophageal cancer KYSE-150, TE-1
Breast cancer Hs 578T, ZR-75-1, SK-BR-3, MDA-MB-468, MDA-MB-453, MDA-MB-231, MCF-7,BT-474, T-47D, HCC1937, etc.
Stomach cancer SNU-1, NCI-N87, KATO III, AGS
Liver cancer Hep G2, Hep 3B2.1-7, SK-HEP-1, PLC/PRF/5
Lung cancer NCI-H1299, NCI-H1650, NCI-H292, HCC827, A549, SK-MES-1, Calu-3, NCI-H1975, SHP-77, T84, etc.
Gallbladder cancer GBC-SD
Pancreatic cancer SW 1990, PANC-1, CFPAC-1, BxPC-3, AsPC-1
Prostate cance PC-3, VCaP, 22RV1, LNCaP
Kidney cancer Caki-1, 786-O, ACHN, 769-P, SW-13
Ovarian cancer SK-OV-3, OVCAR-3, ES-2
Cervical cancer C-33 A, MS751, SiHa, Ca Ski, HeLa, ME-180
Bladder cancer 5637, UM-UC-3, SW 780, J82, T24, SCaBER
Colon cancer SW480, SW620, LoVo, HT-29, HCT 116, COLO 205, RKO-E6, RKO-AS45-1, SW1116,RKO, T84, etc.
Rectal adenocarcinoma DLD-1, Caco-2, COLO 320DM, HCT-15, H716
Choriocarcinoma JEG-3, JAR
Endometrial carcinoma HEC-1-A, HEC-1-B
Leukemia HL-60, A3, HuT 78, Jurkat Clone E6-1, 6T-CEM, THP-1, HEL, MOLT-4, CCRF-CEM, K-562, CEM/C1, MV-4-11

Service Process —— Cell proliferation and viability assays

You can flexibly choose services or personalized services according to your own needs. If you have any questions, please do not hesitate to contact us.