1. Protein Tyrosine Kinase/RTK
    Stem Cell/Wnt
  2. PKA

PKA

PKA (Protein kinase A) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP-dependent protein kinase. Protein kinase A has several functions in the cell, including regulation of glycogen, sugar, and lipid metabolism.

PKA Related Products (13):

Cat. No. Product Name Effect Purity
  • HY-15141
    Staurosporine Inhibitor 99.98%
    Staurosporine is a very potent universal inhibitor of protein kinases but showing little selectivity, with IC50 of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase, respectively.
  • HY-15979A
    H-89 dihydrochloride Inhibitor 98.71%
    H-89 (dihydrochloride) is a potent inhibitor of cyclic AMP-dependent protein kinase (protein kinase A) with IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase, and others kinases.
  • HY-15431
    AZD5363 Inhibitor
    AZD5363 is a potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1,2 and 3, respectively.
  • HY-15727
    Afuresertib Inhibitor 98.91%
    Afuresertib is an orally available, ATP-competitive, pan-AKT inhibitor with Ki of 0.08, 2 and 2.6 nM against AKT1, AKT2 and AKT3, respectively.
  • HY-B0764
    Bucladesine sodium salt Activator 99.33%
    Bucladesine is a membrane permeable selective activator of PKA.
  • HY-100519
    NVS-PAK1-1 Inhibitor 99.82%
    NVS-PAK1-1 is a potent and selective allosteric PAK1 inhibitor with an IC50 of 5 nM.
  • HY-P0291
    Kemptide Phospho-Ser5
    Kemptide (Phospho-Ser5) is a phosphate acceptor peptide that serves as a specific substrate for cAMP-dependent protein kinase (PKA).
  • HY-P0248
    Kemptide
    Kemptide is a synthetic heptapeptide that acts as a specific substrate for cAMP-dependent protein kinase (PKA).
  • HY-100197
    Synaptamide Activator
    Synaptamide is a potent mediator for neurogenic differentiation of NSCs acting through PKA/CREB activation.
  • HY-15727A
    Afuresertib hydrochloride Inhibitor
    Afuresertib hydrochloride is an orally available, ATP-competitive, pan-AKT inhibitor with Ki of 0.08, 2 and 2.6 nM against AKT1, AKT2 and AKT3, respectively.
  • HY-B0764A
    Bucladesine calcium salt Activator
    Bucladesine calcium salt(DC2797 calcium salt) is a membrane permeable selective activator of PKA.
  • HY-18991
    CCG215022 Inhibitor
    CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, GRK5 and GRK1, respectively.
  • HY-15979
    H 89 Inhibitor
    H-89 is a potent inhibitor of cyclic AMP-dependent protein kinase (protein kinase A) with IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase, and others kinases.