1. Protein Tyrosine Kinase/RTK
    Stem Cell/Wnt
  2. PKA

PKA

PKA (Protein kinase A) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP-dependent protein kinase. Protein kinase A has several functions in the cell, including regulation of glycogen, sugar, and lipid metabolism.

PKA Related Products (17):

Cat. No. Product Name Effect Purity
  • HY-15141
    Staurosporine Inhibitor 99.98%
    Staurosporine is a very potent universal inhibitor of protein kinases but showing little selectivity, with IC50 of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase, respectively.
  • HY-15979A
    H-89 dihydrochloride Inhibitor 98.94%
    H-89 (dihydrochloride) is a potent inhibitor of cyclic AMP-dependent protein kinase (protein kinase A) with IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase, and others kinases.
  • HY-10341
    Fasudil Hydrochloride Inhibitor 99.92%
    Fasudil Hydrochloride is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
  • HY-B0764
    Bucladesine sodium salt Activator 99.33%
    Bucladesine is a membrane permeable selective activator of PKA.
  • HY-12059
    AT7867 Inhibitor 98.68%
    AT7867 is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC50s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.
  • HY-P1595
    CREBtide
    CREBtide, a synthetic 13 amino acid peptide, has been reported as a PKA substrate.
  • HY-B0764A
    Bucladesine calcium salt Activator
    Bucladesine calcium salt(DC2797 calcium salt) is a membrane permeable selective activator of PKA.
  • HY-18991
    CCG215022 Inhibitor 98.05%
    CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, GRK5 and GRK1, respectively.
  • HY-100197
    Synaptamide Activator >98.0%
    Synaptamide is a potent mediator for neurogenic differentiation of NSCs acting through PKA/CREB activation.
  • HY-16071
    AT13148 Inhibitor 99.46%
    AT13148 is an orally active and ATP-competitive, multi-AGC kinase inhibitor with IC50s of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively.
  • HY-100984
    HA-100 Inhibitor 99.76%
    HA-100 is an inhibitor of cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), Protein kinase C (PKC) and MLC-kinase with IC50s of 4, 8, 12 and 240 μM, respectively.
  • HY-15979
    H 89 Inhibitor
    H-89 is a potent inhibitor of cyclic AMP-dependent protein kinase (protein kinase A) with IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase, and others kinases.
  • HY-P0248
    Kemptide >98.0%
    Kemptide is a synthetic heptapeptide that acts as a specific substrate for cAMP-dependent protein kinase (PKA). Sequence: Leu-Arg-Arg-Ala-Ser-Leu-Gly.
  • HY-N1074
    Warangalone Inhibitor >98.0%
    Warangalone is an anti-malarial compound which can inhibit the growth of both strains of parasite 3D7 (chloroquine sensitive) and K1 (chloroquine resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively. Warangalone can also inhibit cyclic AMP-dependent protein kinase catalytic subunit (cAK) with an IC50 of 3.5 μM.
  • HY-12059A
    AT7867 dihydrochloride Inhibitor 99.77%
    AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC50s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.
  • HY-10341A
    Fasudil Inhibitor
    Fasudil is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
  • HY-P0291
    Kemptide Phospho-Ser5
    Kemptide (Phospho-Ser5) is a phosphate acceptor peptide that serves as a specific substrate for cAMP-dependent protein kinase (PKA). Sequence: Leu-Arg-Arg-Ala-pSer-Leu-Gly.
Isoform Specific Products

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.