2. Signaling Pathways
  3. Stem Cell/Wnt
  4. PKA
  5. PKA Isoform

PKA

 

PKA Related Products (67):

Cat. No. Product Name Effect Purity
  • HY-15979A
    H-89 dihydrochloride
    		Inhibitor 99.34%
    H-89 dihydrochloride is a potent and selective inhibitor of protein kinase A (PKA) with an IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase.
  • HY-B0764
    Bucladesine sodium
    		Activator 99.48%
    Bucladesine sodium salt (Dibutyryl-cAMP sodium salt) is a stabilized cyclic AMP (cAMP) analog and a selective PKA activator.
  • HY-12306
    8-Bromo-cAMP sodium salt
    		Activator 99.91%
    8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt), a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA).
  • HY-10341
    Fasudil Hydrochloride
    		Inhibitor 99.96%
    Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively.
  • HY-B0764A
    Bucladesine calcium
    		Activator
    Bucladesine calcium salt (Dibutyryl-cAMP calcium salt;DC2797 calcium salt) is a cell-permeable cyclic AMP (cAMP) analog and selectively activates cAMP dependent protein kinase (PKA) by increasing the intracellular level of cAMP.
  • HY-16071
    AT13148
    		Inhibitor 99.42%
    AT13148 is an orally active and ATP-competitive, multi-AGC kinase inhibitor with IC50s of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively.
  • HY-N6789
    KT5720
    		Inhibitor ≥99.0%
    KT5720 is a potent, cell-permeable, specific, reversible and ATP-competitive PKA inhibitor (IC50=3.3 µM).
  • HY-18991
    CCG215022
    		Inhibitor 98.69%
    CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, GRK5 and GRK1, respectively.
  • HY-N0281
    Daphnetin
    		Inhibitor 99.86%
    Daphnetin (7,8-dihydroxycoumarin), one coumarin derivative can be found in plants of the Genus Daphne, is a potent, oral active protein kinase inhibitor, with IC50s of 7.67 μM, 9.33 μM and 25.01 μM for EGFR, PKA and PKC in vitro, respectively.
  • HY-12059
    AT7867
    		Inhibitor 99.88%
    AT7867 is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC50s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.
  • HY-100530D
    Rp-cAMPS sodium salt
    		Antagonist 99.98%
    Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 µM and 4.5 µM, respectively) antagonist.
  • HY-P0222
    PKI(5-24)
    		Inhibitor 99.94%
    PKI(5-24) is a potent, competitive, and synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase), with a Ki of 2.3 nM.
  • HY-P1291
    PKI 14-22 amide,myristoylated
    		Inhibitor 99.65%
    PKI 14-22 amide,myristoylated is a potent cAMP-dependent PKA inhibitor.
  • HY-P1290A
    PKA Inhibitor Fragment (6-22) amide TFA
    		Inhibitor 99.11%
    PKA Inhibitor Fragment (6-22) amide TFA is an inhibitor of cAMP-dependent protein kinase A (PKA), with a Ki of 2.8 nM.
  • HY-N6727
    Gliotoxin
    		Activator 99.51%
    Gliotoxin is a secondary metabolite, the most abundant mycotoxin secreted by A.
  • HY-P1291A
    PKI 14-22 amide,myristoylated TFA
    		Inhibitor 99.86%
    PKI 14-22 amide,myristoylated TFA is a potent cAMP-dependent PKA inhibitor.
  • HY-B1898
    Metadoxine
    		99.38%
    Metadoxine blocks adipocyte differentiation in association with inhibition of the protein kinase A-cAMP response element binding protein (PKA-CREB) pathway.
  • HY-N6791
    KT5823
    		Inhibitor 99.68%
    KT5823, a selective the cGMP-dependent protein kinase (PKG) inhibitor with an Ki value of 0.23 μM, it also inhibits PKA and PKC with Ki values of 10 μM and 4 μM, respectively.
  • HY-100530C
    Sp-cAMPS sodium salt
    		Activator 98.73%
    Sp-cAMPS sodium salt, a cAMP analog, is potent activator of cAMP-dependent PKA I and PKA II.
  • HY-12059A
    AT7867 dihydrochloride
    		Inhibitor 99.17%
    AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC50s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.