1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. PPAR
  4. PPARα Isoform

PPARα

 

PPARα Related Products (54):

Cat. No. Product Name Effect Purity
  • HY-14649
    Retinoic acid
    Agonist 99.74%
    Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis.
  • HY-16578
    GW9662
    Antagonist 99.87%
    GW9662 is a potent and selective PPARγ antagonist with an IC50 of 3.3 nM, showing 10 and 1000-fold selectivity over PPARα and PPARδ, respectively.
  • HY-13956
    Pioglitazone
    Activator 99.66%
    Pioglitazone (U 72107) is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.
  • HY-17356
    Fenofibrate
    Agonist 99.92%
    Fenofibrate is a selective PPARα agonist with an EC50 of 30 μM.
  • HY-15372
    GW6471
    Antagonist 98.81%
    GW6471 is a potent PPARα antagonist.
  • HY-13956B
    Pioglitazone potassium
    Agonist
    Pioglitazone (U 72107) potassium is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 μM and 0.99 μM for human and mouse PPARγ, respectively.
  • HY-143239
    PPARα/γ agonist 1
    Agonist
    PPARα/γ agonist 1 is a potent and dual PPARα/γ partial agonist with EC50 values of 28 nM and 69 nM for PPARα and PPARγ, respectively.
  • HY-13202
    T0070907
    Antagonist 99.98%
    T0070907 is a potent PPARγ antagonist with a Ki of 1 nM.
  • HY-16995
    Pirinixic acid
    Agonist 99.80%
    Pirinixic acid (Wy-14643) is a potent agonist of PPARα, with EC50s of 0.63 μM, 32 μM for murine PPARα and PPARγ, and 5.0 μM, 60 μM, 35 μM for human PPARα, PPARγ and PPARδ, respectively.
  • HY-N0019
    Daidzein
    Activator 99.89%
    Daidzein is a soy isoflavone, which acts as a PPAR activator.
  • HY-16737
    Elafibranor
    Agonist 99.00%
    Elafibranor (GFT505) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively.
  • HY-N0014
    Icariin
    Activator 99.06%
    Icariin is a flavonol glycoside.
  • HY-104049
    Lanifibranor
    Agonist 99.56%
    Lanifibranor is a pan peroxisome proliferator-activated receptor (PPAR) agonist with EC50s of 1.5, 0.87 and 0.21 μM for human PPARα, PPARσ and PPARγ, respectively.
  • HY-13928
    GW0742
    Agonist 99.95%
    GW0742 is a potent PPARβ and PPARδ agonist, with an IC50 of 1 nM for human PPARδ in binding assay, and EC50s of 1 nM, 1.1 μM and 2 μM for human PPARδ, PPARα, and PPARγ, respectively.
  • HY-13861
    GW7647
    Agonist 98.22%
    GW7647 is a potent PPARα agonist, with EC50s of 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ and PPARδ, respectively.
  • HY-B0637
    Bezafibrate
    Agonist 99.43%
    Bezafibrate is an agonist of PPAR, with EC50s of 50 μM, 60 μM, 20 μM for human PPARα, PPARγ and PPARδ, and 90 μM, 55 μM, 110 μM for murine PPARα, PPARγ and PPARδ, respectively; Bezafibrate is used as an hypolipidemic agent.
  • HY-15725
    CDDO-Im
    Activator 98.19%
    CDDO-Im (RTA-403) is an activator of Nrf2 and PPAR, with Kis of 232 and 344 nM for PPARα and PPARγ.
  • HY-N0783
    Eupatilin
    Agonist 98.49%
    Eupatilin, a lipophilic flavonoid isolated from Artemisia argyi Lévl.
  • HY-14601
    Pioglitazone hydrochloride
    Agonist 99.75%
    Pioglitazone hydrochloride is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.
  • HY-N2341
    Palmitelaidic Acid
    Activator ≥99.0%
    Palmitelaidic Acid (9-trans-Hexadecenoic acid) is the trans isomer of palmitoleic acid.