2. Signaling Pathways
  3. Cell Cycle/DNA Damage
    Vitamin D Related/Nuclear Receptor
  4. PPAR
  5. PPARδ Isoform

PPARδ

 

PPARδ Related Products (3):

Cat. No. Product Name Effect Purity
  • HY-141494
    Pparδ agonist 5
    		Agonist
    Pparδ agonist 5, an orally active PPARδ-selective agonist (EC50=0.335 μM), is much greater than that of the prototypical standard GW0742. Pparδ agonist 5 promotes improvements in bone density and microarchitecture in vivo.
  • HY-147757
    PPARγ/δ modulator 1
    		Modulator
    PPARγ/δ modulator 1 (compound 3e) is a potent PPAR modulator. PPARγ/δ modulator 1 is a PPARδ antagonist and a PPARγ partial agonist , with Ki values of 14.4 nM and 5.31 μM, respectively. PPARγ/δ modulator 1 has the EC50 of 7.3 and 12.6 μM for PPARδ corepression and adiponectin production, respectively.
  • HY-144111
    PPARα/δ agonist 1
    		Agonist
    PPARα/δ agonist 1 is a potent PPARα/PPARδ dual agonist (PPARα EC50=7.0 nM; PPARδ EC50=8.4 nM). PPARα/δ agonist 1 is a high selectivity over PPARγ (PPARγ EC50=1316.1 nM). PPARα/δ agonist 1 has the potential for the research of nonalcoholic steatohepatitis.