HSD17B13/PPAR modulator-1
HSD17B13/PPAR modulator-1 (Compound 17) is a HSD17B13/PPAR multitarget modulator. HSD17B13/PPAR modulator-1 is an inhibitor of HSD17B13, with its IC50 value being 0.91 μM. HSD17B13/PPAR modulator-1 is a PPAR agonist, with the EC50 values for PPARα, PPARδ, and PPARγ being 1.55, 0.12, and 0.01 μM respectively. HSD17B13/PPAR modulator-1 can significantly improve liver function, regulate lipid metabolism, alleviate fibrosis, and exert antioxidant and anti-inflammatory effects in the model of metabolic dysfunction-related steatohepatitis (MASH). HSD17B13/PPAR modulator-1 can be used for the study of MASH.
For research use only. We do not sell to patients.
- Formula: C31H29F3N2O5S
- Molecular Weight:598.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PPARα 1.55 μM (EC50) |
PPARδ 0.12 μM (EC50) |
PPARγ 0.01 μM (EC50) |
Chemical Information
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Molecular Weight 598.63
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Formula C31H29F3N2O5S
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SMILES
O=C(C1=C(C)N=C(S1)C2=CC(F)=C(F)C(O)=C2F)N(CC3=CC(C)=C(C(C)=C3)OC(C)(C(O)=O)C)CC4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HSD17B13/PPAR modulator-1 Related Classifications
HY-179015 Related Classifications
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