1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. PPAR
  4. PPARβ/δ Inhibitors

PPARβ/δ Inhibitors

PPARα

PPARβ/δ

PPARγ

PPAR

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform PPARβ/δ together.

Please try each isoform separately.

PPARβ/δ Specific Agonists, Antagonists, Activators & Modulators
Product Name PPARβ/δ PPARα PPARγ PPARβ/δ Selectivity Purity
GW 501516
PPARδ, EC50: 1.1 nM
    Selective Agonist 99.27%
GW0742
PPARδ, EC50: 1 nM
PPARα, EC50: 1.1 μM
PPARγ, EC50: 2 μM
Selective Agonist 97.27%
Pioglitazone
PPARδ, EC50: 0.01 μM (Human PPARδ)
PPARα, EC50: 0.93 μM (Human PPARα)
PPARγ, EC50: 43 μM (Human PPARγ)
Selective Activator 99.18%
GSK3787
PPARδ, pIC50: 6.6 nM
    Selective Antagonist 96.67%
Seladelpar sodium salt
PPAR-δ, EC50: 2 nM
    Selective Agonist 98.52%
L-165041
PPARδ, Ki: 6 nM
 
PPARγ, Ki: 730 nM
Selective Agonist 99.14%
DG172 dihydrochloride
PPARβ/δ, IC50: 27 nM
    Selective Antagonist 99.70%
MA-0204
PPARδ, EC50: 0.4 nM (in human)
PPARδ, EC50: 7.9 nM (in mouse)
PPARδ, EC50: 10 nM (in rat)
    Selective Modulator
Seladelpar
PPAR-δ, EC50: 2 nM
PPAR-α, EC50: 1600 nM
  Selective Agonist
Pparδ agonist 1
PPARδ, EC50: 5.06 nM
    Selective Agonist
Fonadelpar
PPARδ
    Selective Agonist
Pparδ agonist 2
PPARδ
    Selective Agonist
KD-3010
PPARδ
    Selective Agonist
GW9662
PPARδ, IC50: 2000 nM
PPARα, IC50: 32 nM
PPARγ, IC50: 3.3 nM
Pan Antagonist 99.53%
Elafibranor
PPAR-δ, EC50: 175 nM
PPAR-α, EC50: 45 nM
  Pan Agonist 99.18%
Pemafibrate
PPARδ, EC50: 1.58 μM
h-PPARα, EC50: 1 nM
h-PPARγ, EC50: 1.1 μM
Pan Agonist 99.78%
GW7647
PPARδ, EC50: 6.2 μM (Human PPARδ)
PPARα, EC50: 6 nM (Human PPARα)
PPARγ, EC50: 1.1 μM (Human PPARγ)
Pan Agonist 98.04%
Lanifibranor
PPARδ, EC50: 866 nM (Human PPARδ)
PPARα, EC50: 1537 nM (Human PPARα)
PPARγ, EC50: 206 nM (Human PPARγ)
Pan Agonist 98.89%
Fenofibric acid
PPARδ, EC50: 1.06 μM
PPARα, EC50: 22.4 μM
PPARγ, EC50: 1.47 μM
Pan Agonist 99.38%
NXT629
hPPARδ, IC50: 6 μM
hPPARα, IC50: 77 nM
hPPARγ, IC50: 15 μM
Pan Antagonist 99.05%
Indeglitazar
PPARδ
PPARα
PPARγ
Pan Agonist 99.42%
Pemafibrate racemate
h-PPARδ, EC50: 1.7 μM
h-PPARα, EC50: 1 nM
  Pan Agonist
Chiglitazar
PPARδ, EC50: 1.7 μM
PPARα, EC50: 1.8 μM
PPARγ, EC50: 0.08 μM
Pan Agonist
Ertiprotafib
PPARβ, EC50: ~1 μM
PPARα, EC50: ~1 μM
  Pan Agonist