923978-27-2
923978-27-2
Chemical Structure
Elafibranor
Synonym(s): GFT505
- CAS No.: 923978-27-2
- Formula:C22H24O4S
- Molecular Weight:384.49
IUPAC Name: (E)-2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxoprop-1-en-1-yl)phenoxy)-2-methylpropanoic acid
InChIKey: AFLFKFHDSCQHOL-IZZDOVSWSA-N
SMILES: CC(C)(OC1=C(C)C=C(/C=C/C(C2=CC=C(SC)C=C2)=O)C=C1C)C(O)=O
Biological Activity: Elafibranor (GFT505) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis[1].
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Elafibranor | 99.66% | Elafibranor (GFT505) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis. | ||||||||||||||||||||
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Elafibranor (Standard) | ≥98% | Elafibranor (Standard) is the analytical standard of Elafibranor. This product is intended for research and analytical applications. Elafibranor (GFT505) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-16737A(E/Z)-Elafibranor -
Similarity Score 0.74
HY-155525Anti-NASH agent 1 -
Similarity Score 0.62
HY-143862Pparδ agonist 7 -
Similarity Score 0.58
HY-181439SNX3-IN-1 -
Similarity Score 0.57
HY-107397RCh55 (Standard) -
Similarity Score 0.56
HY-N0372Licochalcone A -
Similarity Score 0.56
HY-W792760(E)-2-(4-Cinnamoylphenoxy)acetic acid -
Similarity Score 0.55
HY-156753NorA-IN-1 -
Similarity Score 0.55
HY-13619REfaproxiral (Standard) -
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