Energy Metabolism

Disorders of energy metabolism are characterized by dysregulation in the processing and utilization of energy substrates, impacting essential physiological processes such as enzyme synthesis and hormonal control of energy homeostasis. These disturbances are closely linked to metabolic conditions including type 2 diabetes mellitus and polycystic ovary syndrome, with affected tissues primarily involving skeletal muscle and lung.

References:

[1]. Energy Metabolism. sciencedirect.

Oxidative Phosphorylation (1)

Energy Metabolism (3):

Targets:	Reference Standards (1) Virus Protease (1) Oxidative Phosphorylation (1) SARS-CoV (1) Drug Derivative (1) Mitochondrial Metabolism (1)

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

HY-N0886R

Aloin B (Standard)	28371-16-6
Aloin B (Isobarbaloin) (Standard) is the analytical standard of Aloin B. This product is intended for research and analytical applications. Aloin B is an orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor with an IC₅₀ of 16.08 μM (hydrolytic activity) and 17.51 μM (deubiquitinase activity). Aloin B is metabolized by rat intestinal flora into aloe-emodin-9-anthrone to exert laxative effects. Aloin B inhibits TPA (HY-18739)-induced ear edema, putrescine elevation, and tumor promotion in mouse skin. Aloin B can be used in research related to anti-inflammation, tumor promotion inhibition, coronavirus disease 2019 (COVID-19) and constipation.

HY-W782567

5-Amino-6-(5-phospho-D-ribitylamino)uracil	71491-01-5
5-Amino-6-(5-phospho-D-ribitylamino)uracil is a substance that enhances oxidative phosphorylation or mitochondrial respiration. 5-Amino-6-(5-phospho-D-ribitylamino)uracil can enhance mitochondrial oxidative function. 5-Amino-6-(5-phospho-D-ribitylamino)uracil can be used in the research of cancer.

HY-175128

8-(2-Aminoethylthio)guanosine-5'-O-triphosphate sodium
8-(2-Aminoethylthio)guanosine-5'-O-triphosphate (8-AET-GTP) is a GTP (HY-113225) derivative. GTP is the energy substrate for protein synthesis and gluconeogenesis.

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