3-Phosphoglyceric acid
Based on 1 Customer Validation
3-Phosphoglyceric acid is a metabolic intermediate in both glycolysis and the Calvin cycle. 3-Phosphoglyceric acid is involved in alveolar macrophage epigenetic regulation.
For research use only. We do not sell to patients.
- Purity: 99.88%
- CAS No.: 820-11-1
- Formula: C3H7O7P
- Molecular Weight:186.06
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Metabolism/Protease Compound Library
HY-L012
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Natural Product Library
HY-L021
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Human Endogenous Metabolite Compound Library
HY-L030
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Glycolysis Compound Library
HY-L058
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Gut Microbial Metabolite Library
HY-L078
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Anti-Cancer Metabolism Compound Library
HY-L083
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Microbial Metabolite Library
HY-L084
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Glucose Metabolism Compound Library
HY-L092
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Food-Sourced Compound Library
HY-L094
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Human Metabolite Library
HY-L123
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Animal-Sourced Natural Product Library
HY-L157
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Macrophage Related Compound Library
HY-L174
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Bioactive Compound Library Max
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MCE Bioactive Compound Library
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Natural Product Library Plus
HY-L021P
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Natural Product and Natural Product-Like Compound Library
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Bioactive Compound Library
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RO5 Drug-like Natural Product Library
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High-Throughput Bioactive Compound Library
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Mass Spectrometry Human Endogenous Metabolite Library
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Mass Spectrometry Human Metabolite Library
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Mouse Metabolite Compound Library
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Natural Product Diversity Scaffold Library
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Mass Spectrometry Natural Product Library
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All Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
3-Phosphoglyceric acid (400 μM; 24 hours; BMDMs) treatment enhances Spp1 transcription in VHL-deficient macrophages, and the reduced H3K4me3 modification is also reversed[1].
3-Phosphoglyceric treatment significantly augmentes gene expression as well as H3K4me3 deposition of Spp1 in IL-4-stimulated macrophages[1].
In yeast, 3-Phosphoglyceric acid acts as a metabolic checkpoint for the formation of a multicomponent enzyme complex including serine metabolic enzymes and pyruvate kinase isoform 2 (PKM2) homologue, which senses both serine metabolism and glycolysis and regulates H3K4 methylation and histone phosphorylation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Bone marrow-derived macrophages (BMDMs)
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Concentration:400 µM
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Incubation Time:24 hours
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Result:Enhanced Spp1 transcription in VHL-deficient macrophages, and the reduced H3K4me3 modification was also reversed.
Chemical Information
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CAS No. 820-11-1
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Appearance Viscous Liquid
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Molecular Weight 186.06
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Formula C3H7O7P
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Color Colorless to light yellow
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SMILES
O=C(O)C(O)COP(O)(O)=O
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Synonyms
3-PGA; 3-Glycerophosphoric acid
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 100 mg/mL (537.46 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.3746 mL | 26.8731 mL | 53.7461 mL | 134.3653 mL |
| 5 mM | 1.0749 mL | 5.3746 mL | 10.7492 mL | 26.8731 mL | |
| 10 mM | 0.5375 mL | 2.6873 mL | 5.3746 mL | 13.4365 mL | |
| 15 mM | 0.3583 mL | 1.7915 mL | 3.5831 mL | 8.9577 mL | |
| 20 mM | 0.2687 mL | 1.3437 mL | 2.6873 mL | 6.7183 mL | |
| 25 mM | 0.2150 mL | 1.0749 mL | 2.1498 mL | 5.3746 mL | |
| 30 mM | 0.1792 mL | 0.8958 mL | 1.7915 mL | 4.4788 mL | |
| 40 mM | 0.1344 mL | 0.6718 mL | 1.3437 mL | 3.3591 mL | |
| 50 mM | 0.1075 mL | 0.5375 mL | 1.0749 mL | 2.6873 mL | |
| 60 mM | 0.0896 mL | 0.4479 mL | 0.8958 mL | 2.2394 mL | |
| 80 mM | 0.0672 mL | 0.3359 mL | 0.6718 mL | 1.6796 mL | |
| 100 mM | 0.0537 mL | 0.2687 mL | 0.5375 mL | 1.3437 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
3-Phosphoglyceric acid Related Classifications
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