2. Natural Products
  3. Endogenous metabolite
  4. Human Gut Microbiota Metabolites

Human Gut Microbiota Metabolites

Human Gut Microbiota Metabolites (835):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B2176
    ATP 56-65-5 99.88%
    ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice.
    ATP
  • HY-N0830
    Palmitic acid 57-10-3 99.86%
    Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Palmitic acid is used to establish a cell steatosis model.
    Palmitic acid
  • HY-B2227
    Lactic acid 50-21-5
    Lactic acid (DL-Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid is an oncometabolite and has immune protective role of lactate in anti-tumor immunity. Lactic acid also has antimicrobial activity, which can be used as a food preservative.
    Lactic acid
  • HY-18085
    Quercetin 117-39-5 99.80%
    Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively.
    Quercetin
  • HY-B0150
    Nicotinamide 98-92-0 99.98%
    Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity.
    Nicotinamide
  • HY-116539
    Ketopantolactone 13031-04-4 99.80%
    Ketopantolactone is a biochemical reagent. Ketopantolactone interacts with modified Pt/Al2O3.
    Ketopantolactone
  • HY-N4076
    Dihydrogenistein 21554-71-2
    Dihydrogenistein is a reductive metabolite of Calycosin (HY-N0519), is an active metabolic intermediate.
    Dihydrogenistein
  • HY-128753A
    Lyxose 65-42-9
    Lyxose is a pentose carbohydrate that serves both as a precursor for synthesizing UDP-galactopyranose mutase inhibitors in tuberculosis research and as an inhibitor of hSGLT5-mediated mannose uptake. The content of Lyxose in the cecum of mice fed a Western-style diet decreases.
    Lyxose
  • HY-N0210
    D-Galactose 59-23-4 99.85%
    D-Galactose is a natural aldohexose and C-4 epimer of glucose.
    D-Galactose
  • HY-13417
    AICAR 2627-69-2 99.99%
    AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR is also an autophagy, YAP and mitophagy inhibitor. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR inhibits autophagy through a mechanism independent of AMPK activity.
    AICAR
  • HY-109590
    Arachidonic acid 506-32-1 99.75%
    Arachidonic acid (Immunocytophyt) is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid improves cognitive response and cardiovascular function.
    Arachidonic acid
  • HY-D0187
    L-Glutathione reduced 70-18-8 99.79%
    L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.
    L-Glutathione reduced
  • HY-14650
    DHEA 53-43-0 99.94%
    DHEA (Prasterone) is one of the most abundant steroid hormones. DHEA (Prasterone) mediates its action via multiple signaling pathways involving specific membrane receptors and via transformation into androgen and estrogen derivatives (e.g., androgens, estrogens, 7α and 7β DHEA, and 7α and 7β epiandrosterone derivatives) acting through their specific receptors.
    DHEA
  • HY-F0004
    Fosribnicotinamide 1094-61-7 99.94%
    Fosribnicotinamide (β-nicotinamide mononucleotide) is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD+ intermediate. The pharmacological activities of Fosribnicotinamide include its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity.
    Fosribnicotinamide
  • HY-B2167
    Docosahexaenoic acid 6217-54-5 99.81%
    Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
    Docosahexaenoic acid
  • HY-10197
    Wortmannin 19545-26-7 99.86%
    Wortmannin (SL-2052; KY-12420) is a potent, selective and irreversible PI3K inhibitor with an IC50 of 3 nM. Wortmannin also blocks autophagy formation, and potently inhibits Polo-like kinase 1 (PlK1) and Plk3 with IC50s of 5.8 and 48 nM, respectively.
    Wortmannin
  • HY-B0445
    NAD+ 53-84-9 99.96%
    NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
    NAD+
  • HY-N0162
    Luteolin 491-70-3 99.51%
    Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells.
    Luteolin
  • HY-B1776
    Spermidine 124-20-9 ≥99.0%
    Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2.- contents.
    Spermidine
  • HY-104026
    L-Kynurenine 2922-83-0 99.93%
    L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.
    L-Kynurenine