1. Metabolic Enzyme/Protease
    NF-κB
    Immunology/Inflammation
    Apoptosis
  2. Endogenous Metabolite
    Reactive Oxygen Species
    Ferroptosis
  3. L-Glutathione reduced

L-Glutathione reduced  (Synonyms: GSH; γ-L-Glutamyl-L-cysteinyl-glycine)

Cat. No.: HY-D0187 Purity: 99.83%
COA Handling Instructions

L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

For research use only. We do not sell to patients.

L-Glutathione reduced Chemical Structure

L-Glutathione reduced Chemical Structure

CAS No. : 70-18-8

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Customer Review

Based on 17 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

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Description

L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

L-Glutathione reduced is a non-protein thiol widely exists in living cells. L-Glutathione reduced plays important biological functions in the organism, including protein and DNA synthesis, enzyme activity, metabolism and cell protection. L-Glutathione reduced is capable of scavenging oxygen-derived free radicals and is established to be a marker of oxidative stress[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

307.32

Formula

C10H17N3O6S

CAS No.
SMILES

O=C(O)CNC([[email protected]](CS)NC(CC[[email protected]](N)C(O)=O)=O)=O

Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

H2O : 62.5 mg/mL (203.37 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2539 mL 16.2697 mL 32.5394 mL
5 mM 0.6508 mL 3.2539 mL 6.5079 mL
10 mM 0.3254 mL 1.6270 mL 3.2539 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (325.39 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.83%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
L-Glutathione reduced
Cat. No.:
HY-D0187
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