1. GPCR/G Protein
  2. mGluR

L-Glutamine (Synonyms: L-Glutamic acid 5-amide)

Cat. No.: HY-N0390 Purity: >98.0%
Data Sheet SDS Handling Instructions

L-Glutamine is a non-essential amino acid present abundantly throughout the body and is involved in gastrointestinal disorders.

For research use only. We do not sell to patients.
L-Glutamine Chemical Structure

L-Glutamine Chemical Structure

CAS No. : 56-85-9

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Other Forms of L-Glutamine:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

L-Glutamine is a non-essential amino acid present abundantly throughout the body and is involved in gastrointestinal disorders. Target: mGluR Glutamine (abbreviated as Gln or Q) is one of the 20 amino acids encoded by the standard genetic code. It is not recognized as an essential amino acid, but may become conditionally essential in certain situations, including intensive athletic training or certain gastrointestinal disorders. Its side-chain is an amide formed by replacing the side-chain hydroxyl of glutamic acid with an amine functional group, making it the amide of glutamic acid. Its codons are CAA and CAG. In human blood, glutamine is the most abundant free amino acid, with a concentration of about 500-900 μmol/L. Glutamine is synthesized by the enzyme glutamine synthetase from glutamate and ammonia. The most relevant glutamine-producing tissue is the muscle mass, accounting for about 90% of all glutamine synthesized. Glutamine is also released, in small amounts, by the lung and the brain. Although the liver is capable of relevant glutamine synthesis, its role in glutamine metabolism is more regulatory than producing, since the liver takes up large amounts of glutamine derived from the gut. The most eager consumers of glutamine are the cells of intestines, the kidney cells for the acid-base balance, activated immune cells, and manycancer cells. In respect to the last point mentioned, different glutamine analogues, such as DON, Azaserine or Acivicin, are tested as anticancer drugs.

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References
Molecular Weight

146.14

Formula

C₅H₁₀N₂O₃

CAS No.

56-85-9

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

H2O: ≥ 40 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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L-Glutamine
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