1. GPCR/G Protein
    Neuronal Signaling
    Metabolic Enzyme/Protease
  2. mGluR
    Endogenous Metabolite
  3. L-Glutamine

L-Glutamine (Synonyms: L-Glutamic acid 5-amide)

Cat. No.: HY-N0390 Purity: >98.0%
Handling Instructions

L-Glutamine is a non-essential amino acid present abundantly throughout the body and is involved in gastrointestinal disorders.

For research use only. We do not sell to patients.

L-Glutamine Chemical Structure

L-Glutamine Chemical Structure

CAS No. : 56-85-9

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10 mM * 1 mL in Water USD 66 In-stock
Estimated Time of Arrival: December 31
100 mg USD 60 In-stock
Estimated Time of Arrival: December 31
500 mg USD 96 In-stock
Estimated Time of Arrival: December 31
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Based on 2 publication(s) in Google Scholar

Other Forms of L-Glutamine:

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Description

L-Glutamine is a non-essential amino acid present abundantly throughout the body and is involved in gastrointestinal disorders. Target: mGluR Glutamine (abbreviated as Gln or Q) is one of the 20 amino acids encoded by the standard genetic code. It is not recognized as an essential amino acid, but may become conditionally essential in certain situations, including intensive athletic training or certain gastrointestinal disorders. Its side-chain is an amide formed by replacing the side-chain hydroxyl of glutamic acid with an amine functional group, making it the amide of glutamic acid. Its codons are CAA and CAG. In human blood, glutamine is the most abundant free amino acid, with a concentration of about 500-900 μmol/L. Glutamine is synthesized by the enzyme glutamine synthetase from glutamate and ammonia. The most relevant glutamine-producing tissue is the muscle mass, accounting for about 90% of all glutamine synthesized. Glutamine is also released, in small amounts, by the lung and the brain. Although the liver is capable of relevant glutamine synthesis, its role in glutamine metabolism is more regulatory than producing, since the liver takes up large amounts of glutamine derived from the gut. The most eager consumers of glutamine are the cells of intestines, the kidney cells for the acid-base balance, activated immune cells, and manycancer cells. In respect to the last point mentioned, different glutamine analogues, such as DON, Azaserine or Acivicin, are tested as anticancer drugs.

IC50 & Target

Human Endogenous Metabolite

 

Clinical Trial
Molecular Weight

146.14

Formula

C₅H₁₀N₂O₃

CAS No.

56-85-9

SMILES

N[[email protected]@H](CCC(N)=O)C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 40 mg/mL (273.71 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.8428 mL 34.2138 mL 68.4275 mL
5 mM 1.3686 mL 6.8428 mL 13.6855 mL
10 mM 0.6843 mL 3.4214 mL 6.8428 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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L-Glutamine
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HY-N0390
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