1. GPCR/G Protein
    Neuronal Signaling
    Metabolic Enzyme/Protease
    Apoptosis
  2. mGluR
    Endogenous Metabolite
    Ferroptosis
  3. L-Glutamine

L-Glutamine  (Synonyms: L-Glutamic acid 5-amide)

Cat. No.: HY-N0390 Purity: ≥98.0%
COA Handling Instructions

L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.

For research use only. We do not sell to patients.

L-Glutamine Chemical Structure

L-Glutamine Chemical Structure

CAS No. : 56-85-9

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10 mM * 1 mL in Water USD 66 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 4 publication(s) in Google Scholar

Other Forms of L-Glutamine:

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Description

L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].

IC50 & Target[4]

mGluR

 

Human Endogenous Metabolite

 

In Vitro

L-Glutamine is important as a precursor for peptide and protein synthesis, amino sugar synthesis, purine and pyrimidine and thus nucleic acid and nucleotide synthesis, and also provides a source of carbons for oxidation in some cells. L-Glutamine is the most abundant extracellular amino acid in vivo (0.7 mM compared to an approximate L-glutamate concentration of 20 µM)[1].
In BRIN-BD11 cells, culture for 24 h with 10 mM L-Glutamine compared with 1 mM resulted in substantial changes in gene expression with 148 genes upregulated more than 1.8-fold, and 18 downregulated more than 1.8-fold, including many genes involved in cellular signaling, metabolism, gene regulation, and the insulin-secretory response. L-Glutamine increases the activity of the Ca2+ regulated phosphatase calcineurin and the transcription factor Pdx1[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

146.14

Formula

C5H10N2O3

CAS No.
SMILES

N[[email protected]@H](CCC(N)=O)C(O)=O

Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 33.33 mg/mL (228.07 mM; ultrasonic and adjust pH to 1 with HCl)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.8428 mL 34.2138 mL 68.4275 mL
5 mM 1.3686 mL 6.8428 mL 13.6855 mL
10 mM 0.6843 mL 3.4214 mL 6.8428 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 7.69 mg/mL (52.62 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: ≥98.0%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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L-Glutamine
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HY-N0390
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