DL-Glutamine
Based on 1 Customer Validation
DL-Glutamine ((±)-Glutamine; DL-Gl) is an amino acid metabolite. DL-Glutamine is a plasma metabolic biomarker associated with Treg/Th17 balance in an OVA-induced eosinophilic asthma mouse model. DL-glutamine positively correlates with muscle quality parameters such as muscle water-holding capacity and shear force, and negatively correlates with oxidative stress markers and apoptotic gene expression. DL-Glutamine is associated with periodontal pathogens and oral microbial communities in saliva/serum. DL-Glutamine can be used in research related to asthma, muscle quality, and periodontal disease.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 6899-04-3
- Formula: C5H10N2O3
- Molecular Weight:146.15
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-B1411
i-Inositol -
HY-N0473
L-Tyrosine -
HY-W016562
Hippuric acid -
HY-N0771
L-Isoleucine -
HY-B1346R
DL-Glutamine (Standard) -
HY-N0473R
L-Tyrosine (Standard) -
HY-B1065
Aceglutamide -
HY-100587
D-Glutamine -
HY-14608A
L-Glutamic acid monosodium salt -
HY-N0771R
L-Isoleucine (Standard) -
HY-B1065R
Aceglutamide (Standard) -
HY-100587R
D-Glutamine (Standard)
All Endogenous Metabolite Isoforms
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Biological Activity
Description
IC50 & Target
[2]|
Human Endogenous Metabolite |
Microbial Metabolite |
In Vitro
DL-Glutamine is positively correlated with the salivary bacterium O. uli in the C/MIP multi-omics integration network, and forms significant microbe-metabolite association edges with periodontal pathogens in plaque/saliva[2].
DL-Glutamine is negatively correlated with oxidative stress markers (gpx) and apoptosis genes (casp3/8/9), and positively correlated with muscle quality in the muscle of silver carp under transport stress through integrated transcriptomic-metabolomic analysis[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6899-04-3
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Appearance Solid
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Molecular Weight 146.15
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Formula C5H10N2O3
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Color White to off-white
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SMILES
NC(CCC(N)=O)C(O)=O
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Synonyms
(±)-Glutamine; DL-Gl
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
H2O : 33.33 mg/mL (228.05 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 50 mg/mL (342.11 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (271 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[2]. Alamri MM, et al. Multiomics analyses in young grade C molar incisor pattern periodontitis. J Dent. 2026 Nov;174:106871. [Content Brief]
[3]. Meng Y, et al. Comprehensive transcriptomic and metabolomic analysis provides insight into transportation stress effects on fish muscle quality. NPJ science of food. 2026 Jan 07;10(1):44. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.8423 mL | 34.2114 mL | 68.4229 mL | 171.0571 mL |
| 5 mM | 1.3685 mL | 6.8423 mL | 13.6846 mL | 34.2114 mL | |
| 10 mM | 0.6842 mL | 3.4211 mL | 6.8423 mL | 17.1057 mL | |
| 15 mM | 0.4562 mL | 2.2808 mL | 4.5615 mL | 11.4038 mL | |
| 20 mM | 0.3421 mL | 1.7106 mL | 3.4211 mL | 8.5529 mL | |
| 25 mM | 0.2737 mL | 1.3685 mL | 2.7369 mL | 6.8423 mL | |
| 30 mM | 0.2281 mL | 1.1404 mL | 2.2808 mL | 5.7019 mL | |
| 40 mM | 0.1711 mL | 0.8553 mL | 1.7106 mL | 4.2764 mL | |
| 50 mM | 0.1368 mL | 0.6842 mL | 1.3685 mL | 3.4211 mL | |
| 60 mM | 0.1140 mL | 0.5702 mL | 1.1404 mL | 2.8510 mL | |
| 80 mM | 0.0855 mL | 0.4276 mL | 0.8553 mL | 2.1382 mL | |
| 100 mM | 0.0684 mL | 0.3421 mL | 0.6842 mL | 1.7106 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
DL-Glutamine Related Classifications
HY-B1346 Related Classifications
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Keywords
- DL-Glutamine
- 6899-04-3
- (±)-Glutamine
- DL-Gl
- Endogenous Metabolite
- silver carp muscle
- molar incisor pattern periodontitis
- eosinophilic asthma
- salivary bacterium O.uli
- periodontal pathogens
- Treg/Th17 balance
- plasma metabolite biomarker
- periodontitis pathogenesis
- oral microbial communities
- amino acid metabolite
- Inhibitor
- inhibitor
- inhibit