1. Screening Libraries
  2. Anti-tuberculosis Compound Library

Anti-tuberculosis Compound Library

Cat. No.: HY-L142
Library Contents: XLSX PDF SDF

Tuberculosis (TB), usually caused by bacteria (Mycobacterium tuberculosis), is an infectious disease that mainly affects the lungs. According to the statistics of the World Health Organization (WHO), 10 million people suffer from tuberculosis every year, and 1.5 million people die of tuberculosis every year, which makes tuberculosis the number one killer of infectious diseases.

Tuberculosis can be cured through the standard 6-month course of treatment of four kinds of antibiotics. Common drugs include rifampicin and isoniazid. In some cases, TB bacteria do not respond to standard drugs, that is, patients with drug-resistant tuberculosis. The treatment of drug-resistant tuberculosis takes longer and is more complex. In the face of the resurgence of tuberculosis in the world and the rapid emergence of multi drug resistant tuberculosis, it is very important to develop new anti-tuberculosis drugs or new clinical treatment schemes for existing anti mycobacterium drugs.

MCE supplies a unique collection of 96 compounds with clear anti-tuberculosis activity. MCE Anti-tuberculosis Compound Library is a useful tool for anti-tuberculosis related research and anti-tuberculosis drug development

MCE Anti-tuberculosis Compound Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 95 compounds supplied in 10 mM solution and 1 compounds supplied in 2 mM solution.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, and 2 mM for compounds with solubility between 2 mM and 10 mM.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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50 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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2 × 100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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Description
& Advantages

•    A unique collection of 96 anti-tuberculosis compounds for high throughput screening (HTS) and high content screening (HCS).

•    A useful tool for new anti-tuberculosis drugs discovery.

•   Target diverse, medicinally active and cell permeable.

•   Bioactivity and safety confirmed by preclinical research and clinical trials.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

Product Details
Formulation:
A collection of 96 anti-tuberculosis related compounds supplied as pre-dissolved Solutions or Solid
Solution: 95 compounds supplied in 10 mM solution, 1 compounds supplied in 2 mM solution.
Layout:
96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
In solvent: -80°C 2 years, -20°C 1 year; Powder: -20°C 3 years, 4°C 2 years
Shipping:
Blue ice
Documentation

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    Product Name:
    Anti-tuberculosis Compound Library
    Cat. No.:
    HY-L142
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Storage Tubes with Rack