Tonifying Traditional Chinese Medicine Monomer Compound Library

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Based on 83 publication(s) in Google Scholar

Tonifying traditional Chinese medicines occupy a central position in the traditional medical system, with their core value lying in the regulation of the body's functional state. Modern pharmacological studies have confirmed that these medicinal materials and their monomeric components possess multiple biological activities, including bidirectional immune regulation, anti-aging and lifespan extension, neuroprotection and cognitive enhancement, as well as hematopoietic and metabolic regulation. According to the traditional Chinese medicine theory of “strengthening the body’s resistance and consolidating the foundation”, tonifying medicines are mainly classified into four major categories: Qi-tonifying, Blood-tonifying, Yin-tonifying, and Yang-tonifying. This compound library strictly follows this classification system for compound collection.

Monomeric compounds derived from traditional Chinese medicines demonstrate excellent drug-like properties. They naturally possess structural diversity and clearly defined pharmacological activities, which help improve screening success rates and make them ideal tools for studying multi-target synergistic effects. This library contains 1,039 compounds, providing a material basis for investigating synergistic interactions among compounds (network pharmacology) and facilitating the development of multi-target therapeutic strategies for complex diseases such as cancer, neurodegenerative disorders, and metabolic syndrome.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

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Description & Advantages

•    A collection of tonifying Traditional Chinese Medicine monomers, suitable for high-throughput screening (HTS) and high-content screening (HCS).

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

Product Details

Formulation

A collection of 1,039 tonifying Traditional Chinese Medicine monomers supplied as pre-dissolved Solutions or Solid.

Solution: 1,002 compounds supplied in 10 mM solution, 30 compounds supplied in 2 mM solution, 7 compounds supplied in 3 mg/mL solution.

Layout

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates.
This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage
-80°C
Shipping
Blue ice or dry ice

Documentation

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  • Manual

Composition

Apoptosis (248)

Bacterial (143)

NF-κB (127)

Autophagy (106)

Akt (67)

p38 MAPK (56)

COX (52)

Parasite (52)

Fungal (48)

PI3K (43)

Keap1-Nrf2 (39)

ERK (38)

Caspase (37)

JNK (34)

STAT (28)

Amyloid-β (23)

mTOR (23)

PPAR (23)

MMP (20)

AMPK (16)

Antibiotic (15)

SOD (15)

Wnt (15)

JAK (13)

HIV (12)

Mitophagy (11)

β-catenin (11)

HSV (10)

PERK (10)

Tyrosinase (10)

GSK-3 (9)

PKC (9)

VEGFR (9)

HBV (8)

MEK (8)

PARP (8)

SARS-CoV (8)

HSP (7)

MDM-2/p53 (7)

Sirtuin (7)

CDK (6)

iGluR (6)

PKA (6)

c-Myc (5)

nAChR (5)

Src (5)

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200 mg
USD 120
In-stock
Estimated to ship on August 31 More
500 mg
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Consult sales personnel for more information
Bulk Inquiry
500 mg
Get Quote
Consult sales personnel for more information
Bulk Inquiry
Estimated to ship on August 31 More