1. Cell Cycle/DNA Damage
    Stem Cell/Wnt
  2. Casein Kinase

Casein Kinase

Casein Kinases (CKs) are serine/threonine-selective enzymes that function as regulators of signal transduction pathways in most eukaryotic cell types.

Casein Kinase Related Products (14):

Cat. No. Product Name Effect Purity
  • HY-10108
    LY294002 Inhibitor 99.97%
    LY294002 is a broad-spectrum inhibitor of PI3K, with IC50 of 0.5/0.57/0.97 μM for PI3Kα/δ/β, respectively, also potently inhibits CK2 with IC50 of 98 nM.
  • HY-50855
    CX-4945 Inhibitor 98.77%
    CX-4945 is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC50 values of 1 nM against CK2α and CK2α'.
  • HY-14394
    TBB Inhibitor 98.14%
    TBB is a selective inhibitor for the protein kinase CK2 with IC50 of 1.6 μM.
  • HY-10324
    D4476 Inhibitor 99.86%
    D4476 is a potent, selective and cell-permeable inhibitor of casein kinase 1(CK1) with an IC50 value of 0.3 μM in vitro.
  • HY-15535
    DMAT Inhibitor 98.40%
    DMAT is a potent and specific CK2 inhibitor with an IC50 value of 130 nM.
  • HY-14393
    Emodin Inhibitor >98.0%
    Emodin is a broad-spectrum anticancer agent.
  • HY-15490
    PF-670462 Inhibitor 99.28%
    PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations.
  • HY-12774
    IC261 Inhibitor 98.97%
    IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.
  • HY-50855B
    CX-4945 sodium salt Inhibitor 99.98%
    CX-4945 (Silmitasertib) sodium salt is a potent and selective ATP-competitive small molecule protein kinase CK2 inhibitor with a Ki and an IC50 of 0.38 and 1 nM for recombinant human CK2α, respectively.
  • HY-100011
    SR-3029 Inhibitor 98.89%
    SR 3029 is a potent and highly specific CK1δ/CK1ε inhibitor with the IC50 of 97 nM.
  • HY-15704
    LH846 Inhibitor 98.02%
    LH846 is a selective inhibitor of CK1δ (IC50 values are 290 nM, 1.3 uM and 2.5 uM for CK1δ, ε and α); displays no inhibitory activity at CK2.
  • HY-100114
    TA-01 Inhibitor
    TA-01 potently inhibits CK1ε, CK1δ,and p38α (IC50values are 6.4, 6.8, and 6.7 nM respectively).
  • HY-15479
    TTP 22 Inhibitor
    TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 uM/40 nM; shows selectivity for CK2 over JNK3, ROCK1, and MET(IC50> 10 uM).
  • HY-B0183
    Ellagic acid Inhibitor 99.92%
    Ellagic Acid is a cell permeable and strong casein kinase 2 (CK2) inhibitor (Ki = 20 nM) which acts as a potent antioxidant and anti-mutagenic.