1. Endocrinology


Endocrinology diseases are disorders of the endocrine system. Endocrine disorders are often quite complex, involving a mixed picture of hyposecretion and hypersecretion because of the feedback mechanisms involved in the endocrine system. For example, most forms of hyperthyroidism are associated with an excess of thyroid hormone and a low level of thyroid stimulating hormone. Diabetes mellitus, the most frequent endocrinology disease is a predisposing factor for infections. Polycystic ovary syndrome (PCOS) is a common reproductive endocrinology disease.

Endocrinology Related Products (121):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15677
    INT-777 1199796-29-6
    INT-777 is a potent TGR5 agonist with EC50 of 0.82 μM.
  • HY-15371
    Forskolin 66575-29-9
    Forskolin is a potent adenylate cyclase activator, with binding (IC50=41 nM) to and activation (EC50=0.5 μM) of type I adenylyl cyclase.
  • HY-13683
    Mifepristone 84371-65-3
    Mifepristone is a progesterone receptor (PR) antagonist (IC50=0.2 nM) in a T47D cell-based assay, also is a glucocorticoid receptor (GR) antagonist (IC50=2.6 nM) in an A549 cell-based assay.
  • HY-B0141
    Estradiol 50-28-2
    Estradiol is a human sex hormone and steroid, and the primary female sex hormone.
  • HY-13017
    Ivacaftor 873054-44-5
    Ivacaftor is an orally bioavailable CFTR potentiator, used for cystic fibrosis treatment.
  • HY-50691
    GW-1100 306974-70-9
    GW-1100 is a selective GPR40 antagonist with a pIC50 6.9. GW1100 acts as a GPR40 inverse agonist.
  • HY-15295
    TAK-438 1260141-27-2
    TAK-438 is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion.
  • HY-12219
    MSI-1436 186139-09-3
    MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein tyrosine phosphatase 1B (PTB-1B), with IC50 of appr 1 μM, 200-fold preference over TC-PTP (IC50=224 μM).
  • HY-79135
    Pasireotide ditrifluoroacetate
    Pasireotide (ditrifluoroacetate) is a stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively).
    Pasireotide ditrifluoroacetate
  • HY-A0070A
    3,3',5-Triiodo-L-thyronine 6893-02-3
    3,3',5-Triiodo-L-thyronine is the most potent form of thyroid hormone, a potent agonist of both thyroid hormone receptors TRα and Trβ with Kis of 2.3 nM for both.
  • HY-14650
    DHEA 53-43-0
    DHEA is an important source of androgens, and is an effective antiapoptotic factor.
  • HY-15296
    Cabergoline 81409-90-7
    Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).
  • HY-100339
    GSK583 1346547-00-9
    GSK583 is a highly potent and selective inhibitor of RIP2 Kinase, with IC50 of 5 nM.
  • HY-P0014
    Liraglutide 204656-20-2
    Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.
  • HY-13738A
    Raloxifene hydrochloride 82640-04-8
    RaloxifeneHcl(LY156758 Hcl) is a second generation selective estrogen receptor antagonist.
    Raloxifene hydrochloride
  • HY-17571A
    Oxytocin acetate 6233-83-6
    Oxytocin (α-Hypophamine) acetate is a mammalian neurohypophysial hormone; its actions are mediated by specific, high-affinity oxytocin receptors; ligand of oxytocin receptor.
    Oxytocin acetate
  • HY-A0070
    3,3',5-Triiodo-L-thyronine sodium 55-06-1
    3,3',5-Triiodo-L-thyronine (sodium) is the most potent form of thyroid hormone, a potent agonist of both thyroid hormone receptors TRα and Trβ with Kis of 2.3 nM for both.
    3,3',5-Triiodo-L-thyronine sodium
  • HY-17463
    Prednisolone 50-24-8
    Prednisolone is a glucocorticoid with the general properties of the corticosteroids.
  • HY-11027
    MK-0773 606101-58-0
    MK-0773 is a selective androgen receptor modulators (SARMs) that binds to AR with an IC50 of 6.6 nM.
  • HY-A0038
    Lasofoxifene Tartrate 190791-29-8
    Lasofoxifene Tartrate is a non-steroidal selective estrogen receptor modulator (SERM).
    Lasofoxifene Tartrate