1. Endocrinology

Endocrinology

Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Endocrinology Related Products (146):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15371
    Forskolin 66575-29-9 98.52%
    Forskolin is a potent adenylate cyclase activator, with IC50 and EC50 of 41 nM and 0.5 μM for type I adenylyl cyclase, respectively.
    Forskolin
  • HY-15677
    INT-777 1199796-29-6 >98.0%
    INT-777 is a potent TGR5 agonist with an EC50 of 0.82 μM.
    INT-777
  • HY-B0141
    Estradiol 50-28-2 99.91%
    Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females.
    Estradiol
  • HY-13683
    Mifepristone 84371-65-3 98.17%
    Mifepristone is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay.
    Mifepristone
  • HY-A0070A
    3,3',5-Triiodo-L-thyronine 6893-02-3 98.75%
    3,3',5-Triiodo-L-thyronine is a potent agonist of thyroid hormone receptors TRα and TRβ with Kis of 2.3 nM.
    3,3',5-Triiodo-L-thyronine
  • HY-14650
    DHEA 53-43-0 >98.0%
    DHEA is one of the most abundant steroid hormones. DHEA mediates its action via multiple signaling pathways involving specific membrane receptors and via transformation into androgen and estrogen derivatives (e.g., androgens, estrogens, 7α and 7β DHEA, and 7α and 7β epiandrosterone derivatives) acting through their specific receptors.
    DHEA
  • HY-17571A
    Oxytocin acetate 6233-83-6 99.79%
    Oxytocin (α-Hypophamine) acetate is a mammalian neurohypophysial hormone; its actions are mediated by specific, high-affinity oxytocin receptors; ligand of oxytocin receptor.
    Oxytocin acetate
  • HY-13017
    Ivacaftor 873054-44-5 99.75%
    Ivacaftor is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively.
    Ivacaftor
  • HY-A0070
    3,3',5-Triiodo-L-thyronine sodium 55-06-1 98.16%
    3,3',5-Triiodo-L-thyronine sodium is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity.
    3,3',5-Triiodo-L-thyronine sodium
  • HY-17463
    Prednisolone 50-24-8 >98.0%
    Prednisolone is a glucocorticoid with the general properties of the corticosteroids.
    Prednisolone
  • HY-B0469
    Medroxyprogesterone (acetate) 71-58-9 99.02%
    Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.
    Medroxyprogesterone (acetate)
  • HY-12219A
    MSI-1436 lactate 1309370-86-2
    MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein tyrosine phosphatase 1B (PTB-1B), with an IC50 of 1 μM, 200-fold preference over TC-PTP (IC50 of 224 μM).
    MSI-1436 lactate
  • HY-N0019
    Daidzein 486-66-8 99.66%
    Daidzein is a soy isoflavone, which acts as a PPAR activator.
    Daidzein
  • HY-15296
    Cabergoline 81409-90-7 99.47%
    Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).
    Cabergoline
  • HY-100339
    GSK583 1346547-00-9 98.07%
    GSK583 is a highly potent and selective inhibitor of RIP2 Kinase, with IC50 of 5 nM.
    GSK583
  • HY-79135
    Pasireotide ditrifluoroacetate
    Pasireotide (ditrifluoroacetate) is a stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively).
    Pasireotide ditrifluoroacetate
  • HY-15295
    TAK-438 1260141-27-2 99.97%
    TAK-438 is an orally active potassium-competitive acid blocker which inhibits H+, K+-ATPase activity with an IC50 of 19 nM.
    TAK-438
  • HY-12219
    MSI-1436 186139-09-3
    MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein tyrosine phosphatase 1B (PTB-1B), with an IC50 of appr 1 μM, 200-fold preference over TC-PTP (IC50, 224 μM).
    MSI-1436
  • HY-17405
    Alarelin Acetate 79561-22-1 99.61%
    Alarelin acetate is a synthetic GnRH agonist.
    Alarelin Acetate
  • HY-13665
    Leuprolide Acetate 74381-53-6 99.88%
    Leuprolide acetate is a potent gonadotropin-releasing hormone receptor agonist used for the treatment of prostate cancer, endometriosis, uterine fibroids.
    Leuprolide Acetate