1. Endocrinology


Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Endocrinology Related Products (141):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15371
    Forskolin 66575-29-9 98.52%
    Forskolin is a potent adenylate cyclase activator, with binding (IC50=41 nM) to and activation (EC50=0.5 μM) of type I adenylyl cyclase.
  • HY-15677
    INT-777 1199796-29-6 >98.0%
    INT-777 is a potent TGR5 agonist with EC50 of 0.82 μM.
  • HY-B0141
    Estradiol 50-28-2 98.45%
    Estradiol is a human sex hormone and steroid, and the primary female sex hormone.
  • HY-13683
    Mifepristone 84371-65-3 98.17%
    Mifepristone is a progesterone receptor (PR) antagonist (IC50=0.2 nM) in a T47D cell-based assay, also is a glucocorticoid receptor (GR) antagonist (IC50=2.6 nM) in an A549 cell-based assay.
  • HY-13017
    Ivacaftor 873054-44-5 99.75%
    Ivacaftor is an orally bioavailable CFTR potentiator, used for cystic fibrosis treatment.
  • HY-A0070A
    3,3',5-Triiodo-L-thyronine 6893-02-3 99.23%
    3,3',5-Triiodo-L-thyronine is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity.
  • HY-14650
    DHEA 53-43-0 >98.0%
    DHEA is an important source of androgens, and is an effective antiapoptotic factor.
  • HY-A0070
    3,3',5-Triiodo-L-thyronine sodium 55-06-1 99.22%
    3,3',5-Triiodo-L-thyronine sodium is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity.
    3,3',5-Triiodo-L-thyronine sodium
  • HY-17571A
    Oxytocin acetate 6233-83-6 99.55%
    Oxytocin (α-Hypophamine) acetate is a mammalian neurohypophysial hormone; its actions are mediated by specific, high-affinity oxytocin receptors; ligand of oxytocin receptor.
    Oxytocin acetate
  • HY-12219
    MSI-1436 186139-09-3
    MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein tyrosine phosphatase 1B (PTB-1B), with an IC50 of appr 1 μM, 200-fold preference over TC-PTP (IC50, 224 μM).
  • HY-79135
    Pasireotide ditrifluoroacetate
    Pasireotide (ditrifluoroacetate) is a stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively).
    Pasireotide ditrifluoroacetate
  • HY-15295
    TAK-438 1260141-27-2 99.97%
    TAK-438 is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion.
  • HY-100339
    GSK583 1346547-00-9 98.07%
    GSK583 is a highly potent and selective inhibitor of RIP2 Kinase, with IC50 of 5 nM.
  • HY-17463
    Prednisolone 50-24-8 >98.0%
    Prednisolone is a glucocorticoid with the general properties of the corticosteroids.
  • HY-13738A
    Raloxifene hydrochloride 82640-04-8 99.64%
    RaloxifeneHcl(LY156758 Hcl) is a second generation selective estrogen receptor antagonist.
    Raloxifene hydrochloride
  • HY-A0096
    Iloprost 78919-13-8 99.83%
    Iloprost (ZK 36374) is a synthetic analogue of prostacyclin PGI2.
  • HY-N0019
    Daidzein 486-66-8 99.69%
    Daidzein is a soy isoflavone, which acts as a PPAR activator.
  • HY-13665
    Leuprolide Acetate 74381-53-6 99.88%
    Leuprolide acetate (Leuprorelin) is a GnRH analog; leuprolide acetate acts as an agonist at pituitary GnRH receptors.
    Leuprolide Acetate
  • HY-15296
    Cabergoline 81409-90-7 99.47%
    Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).
  • HY-A0038
    Lasofoxifene Tartrate 190791-29-8 99.91%
    Lasofoxifene Tartrate is a non-steroidal selective estrogen receptor modulator (SERM).
    Lasofoxifene Tartrate