1. Induced Disease Models Products GPCR/G Protein Neuronal Signaling Immunology/Inflammation Metabolic Enzyme/Protease
  2. Immunology and Inflammatory Disease Models Digestive System Disease Models Histamine Receptor Endogenous Metabolite
  3. Gastrointestinal Inflammation and Ulcer Models Gastrointestinal Disease Models
  4. Gastric Ulcer Models Duodenal Ulcer Models
  5. Histamine

Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

For research use only. We do not sell to patients.

Histamine Chemical Structure

Histamine Chemical Structure

CAS No. : 51-45-6

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 66 In-stock
Solution
10 mM * 1 mL in Water USD 66 In-stock
Solid
100 mg USD 60 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Customer Review

Based on 8 publication(s) in Google Scholar

Other Forms of Histamine:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

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Description

Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

IC50 & Target

Human Endogenous Metabolite

 

In Vivo

Histamine can be used in animal modeling to construct gastrointestinal ulcer models.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

111.15

Formula

C5H9N3

CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

NCCC1=CN=CN1

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 34 mg/mL (305.89 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.9969 mL 44.9843 mL 89.9685 mL
5 mM 1.7994 mL 8.9969 mL 17.9937 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (899.69 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.99%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 8.9969 mL 44.9843 mL 89.9685 mL 224.9213 mL
5 mM 1.7994 mL 8.9969 mL 17.9937 mL 44.9843 mL
10 mM 0.8997 mL 4.4984 mL 8.9969 mL 22.4921 mL
15 mM 0.5998 mL 2.9990 mL 5.9979 mL 14.9948 mL
20 mM 0.4498 mL 2.2492 mL 4.4984 mL 11.2461 mL
25 mM 0.3599 mL 1.7994 mL 3.5987 mL 8.9969 mL
30 mM 0.2999 mL 1.4995 mL 2.9990 mL 7.4974 mL
40 mM 0.2249 mL 1.1246 mL 2.2492 mL 5.6230 mL
50 mM 0.1799 mL 0.8997 mL 1.7994 mL 4.4984 mL
60 mM 0.1499 mL 0.7497 mL 1.4995 mL 3.7487 mL
80 mM 0.1125 mL 0.5623 mL 1.1246 mL 2.8115 mL
100 mM 0.0900 mL 0.4498 mL 0.8997 mL 2.2492 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Histamine
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HY-B1204
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