1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. Histamine Receptor
  4. H1 Receptor Isoform

H1 Receptor


H1 Receptor Related Products (52):

Cat. No. Product Name Effect Purity
  • HY-B0298A
    Clemastine fumarate
    Antagonist 99.95%
    Clemastine (HS-592) fumarate is a selective histamine H1 receptor antagonist.
  • HY-B1193
    Antagonist 99.91%
    Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM.
  • HY-B0527A
    Amitriptyline hydrochloride
    Inhibitor 99.56%
    Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively.
  • HY-B0539
    Antagonist 99.98%
    Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine.
  • HY-B0801A
    Fexofenadine hydrochloride
    Antagonist 99.70%
    Fexofenadine (MDL-16455) hydrochloride is an orally active and nonsedative H1 receptor antagonist.
  • HY-148825
    NP10679 is a selective, pH dependent GluN2B subunit-specific N-methyl-D-aspartate (NMDA) receptor inhibitor with high oral bioavailability and good brain penetration.
  • HY-14277
    Levocabastine (R 50547) is a potent and selective histamine H1-receptor antagonist.
  • HY-119995
    Chloropyramine is competitive reversible H1 receptor antagonist.
  • HY-17043
    Agonist 99.98%
    Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.
  • HY-10791
    Inhibitor 99.78%
    Ritanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors.
  • HY-B0303A
    Diphenhydramine hydrochloride
    Antagonist 99.90%
    Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect.
  • HY-13511A
    Rupatadine Fumarate
    Antagonist 98.77%
    Rupatadine (UR-12592) Fumarate is a potent, orally active and long-lasting dual PAF/H1 antagonist, with Kis of 0.55 μM and 0.1 μM, respectively.
  • HY-B0674
    Antagonist 99.54%
    Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist.
  • HY-B0352
    Antagonist 99.97%
    Mirtazapine (Org3770) is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent.
  • HY-B0274
    Antagonist 99.13%
    Chlorprothixene is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively.
  • HY-B0462
    Azelastine hydrochloride
    Antagonist 99.93%
    Azelastine hydrochloridem, an antihistamine, is a potent and selective histamine 1 (H1) antagonist.
  • HY-123205
    Antagonist 99.47%
    Oxatomide is a potent and orally active dual H1-histamine receptor and P2X7 receptor antagonist with antihistamine and anti-allergic activity.
  • HY-10121
    Antagonist 99.93%
    Asenapine (Org 5222), an atypical antipsychotic, is an antagonist of serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4) and histamine receptors (pKi: 8.2-9.0).
  • HY-B0274A
    Chlorprothixene hydrochloride
    Antagonist ≥98.0%
    Chlorprothixene hydrochloride is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively.
  • HY-107647
    (S)-(+)-Dimethindene maleate
    Antagonist 99.94%
    (S)-(+)-Dimethindene maleate, an enantiomer, is a potent M2-selective muscarinic receptor antagonist (pA2 = 7.86/7.74; pKi = 7.78).