1. GPCR/G Protein
    Immunology/Inflammation
  2. Histamine Receptor

Loratadine (Synonyms: SCH 29851; Loratidine)

Cat. No.: HY-17043 Purity: 99.95%
Handling Instructions

Loratadine(SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.

For research use only. We do not sell to patients.

Loratadine Chemical Structure

Loratadine Chemical Structure

CAS No. : 79794-75-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
10 mg USD 60 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
50 mg USD 144 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
100 mg USD 228 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Loratadine(SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. IC50 value: 32 uM Target: H1-receptor Loratadine is a non-sedative antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells.

Clinical Trial
Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6118 mL 13.0589 mL 26.1178 mL
5 mM 0.5224 mL 2.6118 mL 5.2236 mL
10 mM 0.2612 mL 1.3059 mL 2.6118 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

382.88

Formula

C₂₂H₂₃ClN₂O₂

CAS No.

79794-75-5

SMILES

O=C(N1CC/C(CC1)=C2C3=CC=C(Cl)C=C3CCC4=CC=CN=C4\2)OCC

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Loratadine
Cat. No.:
HY-17043
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Loratadine

Cat. No.: HY-17043