Loratadine-d5-1
Loratadine-d5-1 is a deuterated labeled Loratadine (HY-17043). Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.
For research use only. We do not sell to patients.
- CAS No.: 1020719-57-6
- Formula: C22H18D5ClN2O2
- Molecular Weight:387.91
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1020719-57-6
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Unlabeled Cas 79794-75-5
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Molecular Weight 387.91
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Formula C22H18D5ClN2O2
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SMILES
O=C(N1CC/C(CC1)=C2C3=CC=C(Cl)C=C3CC([2H])([2H])C4=C([2H])C([2H])=C([2H])N=C4\2)OCC
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Synonyms
Loratidine-d5-1; SCH 29851-d5-1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Loratadine-d5-1 Related Classifications
HY-23188 Related Classifications
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