2. Oligonucleotides
  3. Solubilizing Agents

Solubilizing Agents

Solubilizing Agents (25):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-Y1891
    Tween 80 9005-65-6
    Tween 80 (Polysorbate 80), a surfactant, has been widely used as a solvent for pharmacological experiments. Tween 80 can also reduce bacterial attachment and inhibit biofilm formation.
    Tween 80
  • HY-101103
    HP-β-CD 128446-35-5 99.74%
    HP-β-CD ((2-Hydroxypropyl)-β-cyclodextrin) is a widely used drug delivery vehicle to improve the stability and bioavailability.
    HP-β-CD
  • HY-Y1890
    Cremophor EL-40 61791-12-6 99.59%
    Cremophor EL-40, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-40 is widely employed to improve dissolution and delivery of agents.
    Cremophor EL-40
  • HY-N0455
    L-Arginine 74-79-3 99.89%
    L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis.
    L-Arginine
  • HY-N0623
    L-Tryptophan 73-22-3 99.99%
    L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels.
    L-Tryptophan
  • HY-D1005A
    Poloxamer 188 9003-11-6
    Poloxamer 188 is a nonionic linear copolymer with surfactant properties. Poloxamer 188 exhibits anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models. Poloxamer 188 can be used for drug delivery.
    Poloxamer 188
  • HY-D1005
    Poloxamer 407 (F127) 9003-11-6
    Poloxamer 407 (F127) is a nonionic surfactant that is 100% active and relatively non-toxic to cells at low concentrations, and frequently used with dye AM esters such as Indo-1 AM, Fura-2 AM, Calcein AM, Fluo-3 AM, Fluo-4 AM, Quest Fluo-8 AM and Quest Rhod-4 AM, etc. to improve their water solubility. Poloxamer 407 is also a lipoprotein lipase inhibitor.
    Poloxamer 407 (F127)
  • HY-141415
    Tween 20 9005-64-5 98.0%
    Tween 20 (Polysorbate 20) is a polyoxyethylene (POE)-type nonionic surfactant.
    Tween 20
  • HY-N0832
    L-Histidine 71-00-1 99.97%
    L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
    L-Histidine
  • HY-N0666
    L-Aspartic acid 56-84-8 99.88%
    L-Aspartic aicd is an amino acid. L-Aspartic aicd is commonly used for preparing prodrugs to target colon and cecal tissues. L-Aspartic aicd commonly used in the study of inflammatory conditions.
    L-Aspartic acid
  • HY-N0717
    L-Valine 72-18-4 99.89%
    L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase.
    L-Valine
  • HY-N0667
    L-Asparagine 70-47-3 98.0%
    L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
    L-Asparagine
  • HY-B2232
    Benzalkonium chloride (51% in water) 8001-54-5 98.0%
    Benzalkonium (Alkyldimethylbenzylammonium) chloride (51% in water) is a quaternary ammonium preservative, cationic surfactant, and antimicrobial (Antimicrobial) agent. Benzalkonium chloride (51% in water) is toxic.
    Benzalkonium chloride (51% in water)
  • HY-W040040
    γ-Cyclodextrin 17465-86-0 99.93%
    γ-Cyclodextrin is an orally active cyclic oligosaccharide composed of eight glucose molecules, which can be formed by bacteria digesting starch. γ-Cyclodextrin can form water-soluble inclusion complexes with a variety of poorly soluble compounds and is widely used in fields such as pharmacy and food. In addition, γ-Cyclodextrin has good safety.
    γ-Cyclodextrin
  • HY-N5139
    Lecithins, egg 93685-90-6 99.0%
    Lecithins, egg (Lecithins, egg yolk; Belovo PL 85) is an orally active natural phospholipid mixture extracted from egg yolks. Lecithins, egg inhibits the activities of acetylcholinesterase (AChE) and angiotensin-converting enzyme (ACE). Lecithins, egg exhibits antibacterial, antioxidant and anti-inflammatory activities, and helps delay cellular senescence. Lecithins, egg enhances nerve conduction, improves memory and cognitive function, and exerts positive effects on delaying neurodegenerative diseases. Lecithins, egg promotes lipid absorption and alleviates diarrhea. Lecithins, egg acts as a high-efficiency drug carrier for the preparation of targeted drug delivery systems such as liposomes.
    Lecithins, egg
  • HY-154644
    Soya Lecithin 8030-76-0
    Soya Lecithin is a phospholipid mixture that can be used as a drug delivery vehicle and is a pharmaceutical excipient. Soya Lecithin can form a lipid bilayer structure through self-assembly, and its binding properties are amphiphilic (hydrophilic head and hydrophobic tail), encapsulating hydrophobic drugs. Soya Lecithin forms stable nanoliposomes or microemulsions, improves the solubility and cellular uptake efficiency of poorly soluble drugs (such as Curcumin (HY-N0005)), and exerts activities such as enhancing drug delivery and regulating cell proliferation.
    Soya Lecithin
  • HY-101530C
    Polyoxyl 100 stearate 9004-99-3 98.0%
    Polyoxyl 100 stearate (PEG-100 stearate) is a non-ionic surfactant formed by polyethylene glycol (PEG) and stearic acid, and it is commonly used in pharmaceutical preparations, nanocarriers, emulsification systems and cosmetic formulations.
    Polyoxyl 100 stearate
  • HY-W129593
    Sorbitan monooctadecanoate 1338-41-6
    Sorbitan monooctadecanoate (Sorbitan monostearate) is a hydrophobic nonionic surfactant. Sorbitan monooctadecanoate can serve as a pharmaceutical excipient, such as an emulsifier, nonionic surfactant, solubilizer, wetting agent, and dispersing/suspending agent.
    Sorbitan monooctadecanoate
  • HY-154639
    Polyoxyl 20 Cetostearyl Ether 68439-49-6
    Polyoxyl 20 Cetostearyl Ether can be used as an excipient, such as Emulsifier and solubilizer for emulsions and creams, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.
    Polyoxyl 20 Cetostearyl Ether
  • HY-101530B
    Polyoxyl 40 stearate 171286-89-8 98.0%
    Polyoxyl 40 stearate (PEG 40 stearate) is a nonionic surfactant formed by the esterification of stearic acid with polyethylene glycol (PEG) containing approximately 40 ethoxy units, it is widely used in pharmaceutical preparations, nanodrug carriers, emulsification systems and biomedical materials. Polyoxyl 40 stearate can serve as a matrix component of solid lipid nanoparticles to achieve controlled release of encapsulated antifungal drugs; it can also act as a base material for solid lipid nanoparticles for vaginal administration, and polymerizable groups can be introduced via modification with acryloyl chloride.
    Polyoxyl 40 stearate