73-22-3
73-22-3
Chemical Structure
L-Tryptophan
Synonym(s): Tryptophan; Tryptophane
- CAS No.: 73-22-3
- Formula:C11H12N2O2
- Molecular Weight:204.23
IUPAC Name: L-tryptophan
InChIKey: QIVBCDIJIAJPQS-VIFPVBQESA-N
SMILES: N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
Biological Activity: L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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L-Tryptophan | 99.99% | L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels. | ||||||||||||||||||||
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L-Tryptophan (standard) | 99.98% | L-Tryptophan (standard) is the analytical standard of L-Tryptophan. L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels. | ||||||||||||||||||||
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L-Tryptophan-d8 | 98.55% | L-Tryptophan-d8 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. | ||||||||||||||||||||
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L-Tryptophan-13C11,15N2 | 99.9% | L-Tryptophan-13C11,15N2 is the 13C- and 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. | ||||||||||||||||||||
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L-Tryptophan-15N2,d8 | L-Tryptophan-15N2,d8 is the deuterium and 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. | |||||||||||||||||||||
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L-Tryptophan-d3 | 99.98% | L-Tryptophan-d3 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. | ||||||||||||||||||||
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L-Tryptophan-15N | 99.50% | L-Tryptophan-15N is the 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. | ||||||||||||||||||||
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L-Tryptophan-13C11 | 99.80% | L-Tryptophan-13C11 is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. | ||||||||||||||||||||
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L-Tryptophan-d5 | 99.86% | L-Tryptophan-d5 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. | ||||||||||||||||||||
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L-Phenylalanine,Indole-15N | 99.79% | L-Phenylalanine,Indole-15N is the 15N labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. | ||||||||||||||||||||
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L-Tryptophan-1-13C | 99.94% | L-Tryptophan-1-13C is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. | ||||||||||||||||||||
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L-Tryptophan-13C | 99.96% | L-Tryptophan-13C is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. | ||||||||||||||||||||
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L-Tryptophan-15N2 | 99.9% | L-Tryptophan-15N2 is the 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. | ||||||||||||||||||||
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Indolelactic acid-d5 | 99.24% | Indolelactic acid-d5 is the deuterium labeled Indolelactic acid. Indolelactic acid is a tryptophan (Trp) catabolite in Azotobacter vinelandii cultures. | ||||||||||||||||||||
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L-Tryptophanamide | L-Tryptophanamide (H-Trp-NH2) is tryptophanamide hydrochloride, a primary UV standard. L-Tryptophanamide is a metabolite downregulated after fermentation of sea buckthorn juice by Lactobacillus plantarum or Lactiplantibacillus plantarum, and is positively correlated with bitterness and astringency in taste sensory evaluation. L-Tryptophanamide can be used for metabolite analysis and flavor research. | |||||||||||||||||||||
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3-Indoleacetic acid-d5 | 99.76% | 3-Indoleacetic acid-d5 (Indole-3-acetic acid-d5) is the deuterated-labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid is is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis. | ||||||||||||||||||||
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3-Indoleacetic acid-2,2-d2 | 99.06% | 3-Indoleacetic acid-2,2-d2 (Indole-3-acetic acid-2,2-d2) is the deuterated-labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid is is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis. | ||||||||||||||||||||
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3-Indoleacetic acid-d7 | 99.75% | 3-Indoleacetic acid-d7 (Indole-3-acetic acid-d7) is the deuterated-labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid is is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis. | ||||||||||||||||||||
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Serotonin-d4 | 99.61% | Serotonin-d4 is deuterium labeled Serotonin. Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM. | ||||||||||||||||||||
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Serotonin-d4 hydrochloride | 99.22% | Serotonin-d4 (5-Hydroxytryptamine-d4) hydrochloride is the deuterium labeled Serotonin (hydrochloride) (HY-B1473). Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM. | ||||||||||||||||||||
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Serotonin-13C,D4 | Serotonin-13C,D4 (5-Hydroxytryptamine-13C,D4) is a 13C- and deuterated labeled Serotonin (HY-B1473A). Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM. | |||||||||||||||||||||
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DL-3-Phenylalanine-d8 | 99.90% | DL-3-Phenylalanine-d8 is the deuterium labeled DL-3-Phenylalanine. | ||||||||||||||||||||
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Tryptamine-d4 hydrochloride | 99.28% | Tryptamine-d4 (hydrochloride) is the deuterium labeled Tryptamine hydrochloride. Tryptamine hydrochloride, a monoamine alkaloid, similar to other trace amines, is believed to play a role as a neuromodulator or neurotransmitter. | ||||||||||||||||||||
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L-Phenylalanine-d8 | 99.9% | L-Phenylalanine-d8 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals. | ||||||||||||||||||||
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L-Phenylalanine-d5 | 99.96% | L-Phenylalanine-d5 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals. | ||||||||||||||||||||
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DL-Phenylalanine-d5 | 99.95% | DL-Phenylalanine-d5 is the deuterium labeled DL-Phenylalanine. | ||||||||||||||||||||
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L-Phenylalanine-13C9,15N,d8 | L-Phenylalanine-13C9,15N,d8 is the deuterium, 13C-, and 15-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals. | |||||||||||||||||||||
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L-Tyrosine-d7 | 99.77% | L-Tyrosine-d7 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex. | ||||||||||||||||||||
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5-Hydroxyindole-3-acetic acid-d2 | 98.25% | 5-Hydroxyindole-3-acetic acid-d2 is the deuterium labeled 5-Hydroxyindole-3-acetic acid. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors. | ||||||||||||||||||||
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H-D-Trp-OH | 99.97% | H-D-Trp-OH (D-Tryptophan) is the D-isomer of tryptophan, which is occasionally found in natural peptides, such as marine toxin peptides. H-D-Trp-OH can increase intestinal microbial diversity and counteract the inhibitory effect of allergic airway inflammation on intestinal microbial diversity. | ||||||||||||||||||||
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H-D-Trp-OH (Standard) | ≥98% | H-D-Trp-OH (Standard) is the analytical standard of H-D-Trp-OH. This product is intended for research and analytical applications. H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide. | ||||||||||||||||||||
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H-D-Trp-OH-d5 | H-D-Trp-OH-d5 (D-Tryptophan-d5) is the deuterium labeled H-D-Trp-OH. H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide. | |||||||||||||||||||||
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DL-Tryptophan | 99.96% | DL-Tryptophan ((±)-Tryptophan) is an orally effective aryl hydrocarbon receptor (AhR) agonist. DL-Tryptophan reduces the expression of pro-inflammatory cytokines IL-6, TNF-α, IL-1β, as well as liver injury markers aspartate aminotransferase and alanine aminotransferase, and alleviates hepatocyte apoptosis (apoptosis) in sepsis induced by cecal ligation and puncture. DL-Tryptophan can be used in the research of sepsis-related acute liver injury. | ||||||||||||||||||||
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DL-Tryptophan (Standard) | ≥98% | DL-Tryptophan (Standard) is an analytical standard of DL-Tryptophan. This product is intended for research and analytical applications. DL-Tryptophan ((±)-Tryptophan) is an orally effective aryl hydrocarbon receptor (AhR) agonist. DL-Tryptophan reduces the expression of pro-inflammatory cytokines IL-6, TNF-α, IL-1β, as well as liver injury markers aspartate aminotransferase and alanine aminotransferase, and alleviates hepatocyte apoptosis (apoptosis) in sepsis induced by cecal ligation and puncture. DL-Tryptophan can be used in the research of sepsis-related acute liver injury. | ||||||||||||||||||||
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DL-Tryptophan-d3 | 99.64% | DL-Tryptophan-d3 is the deuterium labeled DL-Tryptophan. DL-Tryptophan ((±)-Tryptophan) is an orally effective aryl hydrocarbon receptor (AhR) agonist. DL-Tryptophan reduces the expression of pro-inflammatory cytokines IL-6, TNF-α, IL-1β, as well as liver injury markers aspartate aminotransferase and alanine aminotransferase, and alleviates hepatocyte apoptosis (apoptosis) in sepsis induced by cecal ligation and puncture. DL-Tryptophan can be used in the research of sepsis-related acute liver injury. | ||||||||||||||||||||
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DL-Tryptophan-d8 | 99.64% | DL-Tryptophan-d8 is the deuterium labeled DL-Tryptophan. DL-Tryptophan ((±)-Tryptophan) is an orally effective aryl hydrocarbon receptor (AhR) agonist. DL-Tryptophan reduces the expression of pro-inflammatory cytokines IL-6, TNF-α, IL-1β, as well as liver injury markers aspartate aminotransferase and alanine aminotransferase, and alleviates hepatocyte apoptosis (apoptosis) in sepsis induced by cecal ligation and puncture. DL-Tryptophan can be used in the research of sepsis-related acute liver injury. | ||||||||||||||||||||
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Tryptamine-d2-1 hydrochloride | Tryptamine-d2-1 hydrochloride is the deuterium labeled Tryptamine hydrochloride (HY-W014971). Tryptamine hydrochloride belongs to the class of indole alkaloids and is a derivative of the amino acid tryptophan. Tryptamine hydrochloride is psychoactive and acts as a neurotransmitter in the body, affecting mood, perception and cognition. In its hydrochloride form, Tryptamine hydrochloride hydrochloride, it is commonly used as a research chemical and as a starting material for the synthesis of other organic compounds. It can also occur naturally in certain plants and animals, including fungi and mammals. Due to the psychoactive properties of Tryptamine hydrochloride and its derivatives, its use and possession are controlled substances in many countries. | |||||||||||||||||||||
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Metyrosine-13C9,15N,d7 | Metyrosine-13C9,15N,d7 is the deuterium, 13C-, and 15-labeled Metyrosine. Metyrosine is a selective tyrosine hydroxylase enzyme inhibitor. Metyrosine exerts anti-inflammatory and anti-ulcerative effects. Metyrosine significantly inhibits high COX-2 activity. Metyrosine is a very effective agent for blood pressure control. | |||||||||||||||||||||
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Methyl 2-(1H-indol-3-yl)acetate-d5 | 99.08% | Methyl 2-(1H-indol-3-yl)acetate-d5 is the deuterium labeled Methyl 2-(1H-indol-3-yl)acetate. Methyl 2-(1H-indol-3-yl)acetate is an endogenous metabolite. | ||||||||||||||||||||
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3-Indolepropionic acid-d2 | 99.88% | 3-Indolepropionic acid-d2 is the deuterium labeled 3-Indolepropionic acid. 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease. | ||||||||||||||||||||
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Indole-3-acetamide-d5 | 99.99% | Indole-3-acetamide-d5 is the deuterium labeled Indole-3-acetamide. Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class. | ||||||||||||||||||||
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DL-Tryptophan-d5 | DL-Tryptophan-d5 ((±)-Tryptophan-d5) is the deuterium labeled DL-Tryptophan (HY-W012480). DL-Tryptophan is an endogenous metabolite. | |||||||||||||||||||||
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Indole-3-pyruvic acid-d5 | 96.31% | Indole-3-pyruvic acid-d5 is deuterated labeled Indole-3-pyruvic acid. Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety. | ||||||||||||||||||||
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Tryptophol-d4 | 99.97% | Tryptophol-d4 (Indole-3-ethanol-d4) is the deuterium labeled Tryptophol (HY-W010155). Tryptophol is an aromatic alcohol and secondary metabolite produced by microorganisms. Tryptophol induces apoptosis and cleavage of caspase-8. Tryptophol inhibits Cunninghamella blakesleeana biofilm. Tryptophol has anti-phage infection, biofilm formation regulation, anti-inflammatory, hemolytic, sleep induction, temperature change, seizure susceptibility and immune regulation activities. Tryptophol is used in the research of African trypanosomiasis, sleep disorders, epilepsy. | ||||||||||||||||||||
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D-Phenylalanine-d5 | 99.87% | D-Phenylalanine-d5 is the deuterium labeled D-Phenylalanine. D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014. | ||||||||||||||||||||
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D-Phenylalanine-d8 | 98.28% | D-Phenylalanine-d8 is the deuterium labeled D-Phenylalanine. D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014. | ||||||||||||||||||||
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DL-Tyrosine-d7 | 99.78% | DL-Tyrosine-d7 is the deuterium labeled DL-Tyrosine. DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine). | ||||||||||||||||||||
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D-Tyrosine-d7 | 97.27% | D-Tyrosine-d7 is the deuterium labeled D-Tyrosine (HY-Y0444). D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth. | ||||||||||||||||||||
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References
- [1]. Kang Xu, et al. L-Tryptophan activates the aryl hydrocarbon receptor and induces cell cycle arrest in porcine trophectoderm cells. Theriogenology. 2021 Sep 1:171:137-146. [Content Brief]
- [2]. Hai Thanh Pham, et al. Tryptophan and Kynurenine Enhances the Stemness and Osteogenic Differentiation of Bone Marrow-Derived Mesenchymal Stromal Cells In Vitro and In Vivo. Materials (Basel). 2021 Jan 4;14(1):208. [Content Brief]
- [3]. Slominski A, et al. Conversion of L-tryptophan to serotonin and melatonin in human melanoma cells. FEBS Lett. 2002 Jan 30;511(1-3):102-6. [Content Brief]
