1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. L-Tryptophan-d5

L-Tryptophan-d5  (Synonyms: Tryptophan-d5; Tryptophane-d5)

Cat. No.: HY-N0623S Purity: 99.85%
COA Handling Instructions

L-Tryptophan-d5 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

For research use only. We do not sell to patients.

L-Tryptophan-d<sub>5</sub> Chemical Structure

L-Tryptophan-d5 Chemical Structure

CAS No. : 62595-11-3

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5 mg USD 350 In-stock
10 mg USD 560 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of L-Tryptophan-d5:

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Description

L-Tryptophan-d5 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

209.26

Formula

C11H7D5N2O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)CC1=C([2H])NC2=C([2H])C([2H])=C([2H])C([2H])=C12)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 33.33 mg/mL (159.28 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7787 mL 23.8937 mL 47.7874 mL
5 mM 0.9557 mL 4.7787 mL 9.5575 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.7787 mL 23.8937 mL 47.7874 mL 119.4686 mL
5 mM 0.9557 mL 4.7787 mL 9.5575 mL 23.8937 mL
10 mM 0.4779 mL 2.3894 mL 4.7787 mL 11.9469 mL
15 mM 0.3186 mL 1.5929 mL 3.1858 mL 7.9646 mL
20 mM 0.2389 mL 1.1947 mL 2.3894 mL 5.9734 mL
25 mM 0.1911 mL 0.9557 mL 1.9115 mL 4.7787 mL
30 mM 0.1593 mL 0.7965 mL 1.5929 mL 3.9823 mL
40 mM 0.1195 mL 0.5973 mL 1.1947 mL 2.9867 mL
50 mM 0.0956 mL 0.4779 mL 0.9557 mL 2.3894 mL
60 mM 0.0796 mL 0.3982 mL 0.7965 mL 1.9911 mL
80 mM 0.0597 mL 0.2987 mL 0.5973 mL 1.4934 mL
100 mM 0.0478 mL 0.2389 mL 0.4779 mL 1.1947 mL
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L-Tryptophan-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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