2. Adjuvant
  3. Monophosphory Lipid A Adjuvant

Monophosphory Lipid A Adjuvant

Lipid A in lipopolysaccharide (LPS) is the primary inducer of inflammatory responses and possesses potent immunostimulatory effects; however, its toxicity limits its application as an immunological adjuvant or therapeutic agent. After hydrolyzing the main active component of LPS, lipid A, the monophosphorylated compound MPL is obtained. The toxicity of MPL is at most 0.08% of that of the parent LPS, while its immunomodulatory activity is largely, if not entirely, retained. MPL has been used as an adjuvant in seven vaccines.

Monophosphory Lipid A Adjuvant (11):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-130320
    Monophosphoryl lipid A 1246298-63-4 99.87%
    Monophosphoryl lipid A (Glucopyranosyl lipid A) is a toll-like receptor 4 agonist. Monophosphoryl lipid A is derived from the cell wall of nonpathogenic Salmonella. Monophosphoryl lipid A can be used for the research of immunization and vaccine.
    Monophosphoryl lipid A
  • HY-N16009
    α-Rhamnosyl FP20 sodium 3056013-95-4
    α-Rhamnosyl FP20 sodium, a TLR-4 agonist, is a vaccine adjuvant.
    α-Rhamnosyl FP20 sodium
  • HY-N16301
    Lipid A (14:0(5)-cyclopropyl17:0(1)) diammonium
    Lipid A (14:0(5)-cyclopropyl17:0(1)) diammonium, a lipid, is an adjuvant. Lipid A (14:0(5)-cyclopropyl17:0(1)) diammonium has immunostimulatory properties.
    Lipid A (14:0(5)-cyclopropyl17:0(1)) diammonium
  • HY-N15893
    α-Galactosyl FP20 sodium 3056013-94-3
    α-Galactosyl FP20 sodium, a TLR-4 agonist, is a vaccine adjuvant.
    α-Galactosyl FP20 sodium
  • HY-N16020
    α-Glucosyl FP20 sodium 3056013-97-6
    α-Glucosyl FP20 sodium, a TLR-4 agonist, is a vaccine adjuvant.
    α-Glucosyl FP20 sodium
  • HY-N16013
    FP-18 disodium 2936622-27-2
    FP-18 disodium, a TLR-4 agonist, is a vaccine adjuvant.
    FP-18 disodium
  • HY-130320B
    Monophosphoryl lipid A Triethylamine
    Monophosphoryl lipid A (Triethylamine) is a toll-like receptor 4 agonist. Monophosphoryl lipid A (Triethylamine) is derived from the cell wall of nonpathogenic Salmonella. Monophosphoryl lipid A (Triethylamine) can be used for the research of immunization and vaccine.
    Monophosphoryl lipid A Triethylamine
  • HY-159672B
    3D-Monophosphoryl Lipid (12,16) triethylamine
    3D-Monophosphoryl Lipid (12,16) (3D-MPL (12,16)) triethylamine is a TLR4 agonist that can be used as a vaccine adjuvant to enhance the immunogenicity of vaccines.
    3D-Monophosphoryl Lipid (12,16) triethylamine
  • HY-159672
    3D-Monophosphoryl Lipid (12,16)
    3D-Monophosphoryl Lipid (12,16) (3D-MPL (12,16)) is a TLR4 agonist that can be used as a vaccine adjuvant to enhance the immunogenicity of vaccines.
    3D-Monophosphoryl Lipid (12,16)
  • HY-N16021
    4A-MPLA ammonium 2260669-09-6
    4A-MPLA ammonium is an orally active TLR4 agonist. 4A-MPLA ammonium induces TLR4 endocytosis dependent on Cdc42 and galectin-3, triggering TRIF-mediated signaling and sustained IFN-β production. 4A-MPLA ammonium promotes lipid droplet formation, upregulates interferon-stimulated genes and type I IFN signaling genes, downregulates lysosome/phagosome function genes, and modulates tolerogenic dendritic cell function. 4A-MPLA ammonium can be used for the research of colitis.
    4A-MPLA ammonium
  • HY-130320A
    Monophosphoryl lipid A free acid 960324-04-3
    Monophosphoryl lipid A (free acid) is a toll-like receptor 4 agonist. Monophosphoryl lipid A (free acid) is derived from the cell wall of nonpathogenic Salmonella. Monophosphoryl lipid A (free acid) can be used for the research of immunization and vaccine.
    Monophosphoryl lipid A free acid