2. Signaling Pathways
  3. Immunology/Inflammation
  4. Galectin
  5. Galectin-3 Isoform

Galectin-3

 

Galectin-3 Related Products (13):

Cat. No. Product Name Effect Purity
  • HY-114409
    GB1107
    		Inhibitor 99.90%
    GB1107 is a potent, selective, orally active inhibitor of Galectin-3 (Gal-3) with a Kd of 37 nM for human Galectin-3. GB1107 reduces human and mouse lung adenocarcinoma growth and blocks metastasis in the syngeneic model.
  • HY-147041
    Selvigaltin
    		Inhibitor 98.72%
    Selvigaltin (GB1211) is an orally available galectin-3 (Gal-3) inhibitor.
  • HY-114440
    Belapectin
    		Inhibitor
    Belapectin (GR-MD-02) is a Galectin-3 (Gal-3) inhibitor. Belapectin drives tumor-induced immunosuppression by inducing T cell Apoptosis. Belapectin promotes tumor regression and improves survival of tumor-bearing mice through a CD8+ T cell-dependent mechanism. Belapectin binds to Gal-3 with affinity Ki of 2.8 μM.
  • HY-P1592A
    G3-C12 TFA
    		99.44%
    G3-C12 (TFA) is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity.
  • HY-146808
    Galectin-3 antagonist 1
    		Antagonist 99.77%
    Galectin-3 antagonist 1 (compound 15) is a potent and selective Galectin-3 (Gal-3) antagonist with Kd value of 5.3 μM. Meanwhile, Galectin-3 antagonist 1 binds to various Galectin with Kd values of 250 μM (Gal-4N), 18 μM (Gal-4C), 450 μM (Gal-8C), respectively.
  • HY-157821
    Galectin-4-IN-3
    		Inhibitor
    Galectin-4-IN-3 (Compound 11) is a Galectin 4C inhibitor, with a Kd of 160 μM.
  • HY-163407
    Galectin-3-IN-4
    		Inhibitor
    Galectin-3-IN-4 (compound 5) is a carboxamide analog. Galectin-3-IN-4 is a potent, selective, and orally bioavailable inhibitor of human and mouse galectin-3, with IC50 values of 21 and 167 nM for hGal-3 and mGal-3, respectively. Galectin-3-IN-4 has IC50 values of 1580 and 2750 nM for hGal-1 and hGal-9, respectively.
  • HY-163405
    Galectin-3-IN-3
    		Inhibitor
    Galectin-3-IN-3 (Compound 4) is an orally active and selective inhibitor of Gal-3, with IC50 values of 11 nM and 84 nM against mGal-3 and hGal-3 respectively.
  • HY-P1592
    G3-C12
    		99.44%
    G3-C12 is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity.
  • HY-144313
    Galectin-3-IN-2
    		Inhibitor
    Galectin-3-IN-2 (Compound 9) is a potent multivalent inhibitor of galectin-3 (Gal-3; IC50=8.3 μM). Galectin-3 participates in many cancer-related metabolic processes.
  • HY-146809
    Galectin-3 antagonist 2
    Galectin-3 is a β Galactoside specific carbohydrate recognition protein (lectin) has the ability to promote the migration of B cell precursor acute lymphoblastic leukemia (BCP-ALL) cells and withstand drug research.
  • HY-144312
    Galectin-3-IN-1
    		Inhibitor 99.76%
    Galectin-3-IN-1 (Compound 1) is a potent multivalent inhibitor of galectin-3 (Gal-3). Galectin-3 participates in many cancer-related metabolic processes. Galectin-3-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • HY-163082
    GB1490
    		Inhibitor
    GB1490 is an orally active galectin inhibitor with Kd values of 0.4 μM and 2.7 μM for galectin-1 and galectin-3, respectively.
Cat. No. Product Name / Synonyms Application Reactivity