1. Immunology/Inflammation
  2. Galectin
  3. G3-C12

G3-C12 

Cat. No.: HY-P1592 Purity: 99.44%
Handling Instructions

G3-C12 is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity.

For research use only. We do not sell to patients.

G3-C12 Chemical Structure

G3-C12 Chemical Structure

CAS No. : 848301-94-0

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Description

G3-C12 is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity.

IC50 & Target

Kd: 88 nM (Galectin-3)[1]

In Vitro

G3-C12 is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins. G3-C12 bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer[1].

Molecular Weight

1758.98

Formula

C₇₄H₁₁₅N₂₃O₂₃S₂

CAS No.

848301-94-0

Sequence

Ala-Asn-Thr-Pro-Cys-Gly-Pro-Tyr-Thr-His-Asp-Cys-Pro-Val-Lys-Arg

Sequence Shortening

ANTPCGPYTHDCPVKR

SMILES

[ANTPCGPYTHDCPVKR]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
References
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Keywords:

G3-C12GalectinInhibitorinhibitorinhibit

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