G3-C12
Based on 1 publication(s) in Google Scholar
G3-C12 is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity.
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- 純度: 99.64%
- CAS 番号: 848301-94-0
- 分子式: C74H115N23O23S2
- 分子量:1758.98
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 G3-C12
MoreGalectin アイソフォーム固有の製品をすべて表示
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生物活性
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Galectin-3 |
G3-C12 is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins. G3-C12 bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 848301-94-0
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性状 Solid
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分子量 1758.98
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分子式 C74H115N23O23S2
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Color White to off-white
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配列
Ala-Asn-Thr-Pro-Cys-Gly-Pro-Tyr-Thr-His-Asp-Cys-Pro-Val-Lys-Arg
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シーケンスの短縮
ANTPCGPYTHDCPVKR
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Transl Med
Myeloid leukemia-derived galectin-1 downregulates CAR expression to hinder cytotoxicity of CAR T cells. [Abstract]2024 Jan 6;22(1):32. PMID: 38184596
溶剤 & 溶解度
H2O : ≥ 100 mg/mL (56.85 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.5685 mL | 2.8426 mL | 5.6851 mL | 14.2128 mL |
| 5 mM | 0.1137 mL | 0.5685 mL | 1.1370 mL | 2.8426 mL | |
| 10 mM | 0.0569 mL | 0.2843 mL | 0.5685 mL | 1.4213 mL | |
| 15 mM | 0.0379 mL | 0.1895 mL | 0.3790 mL | 0.9475 mL | |
| 20 mM | 0.0284 mL | 0.1421 mL | 0.2843 mL | 0.7106 mL | |
| 25 mM | 0.0227 mL | 0.1137 mL | 0.2274 mL | 0.5685 mL | |
| 30 mM | 0.0190 mL | 0.0948 mL | 0.1895 mL | 0.4738 mL | |
| 40 mM | 0.0142 mL | 0.0711 mL | 0.1421 mL | 0.3553 mL | |
| 50 mM | 0.0114 mL | 0.0569 mL | 0.1137 mL | 0.2843 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
G3-C12 関連分類
HY-P1592 関連分類
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