1. Signaling Pathways
  2. Immunology/Inflammation
  3. Galectin
  4. Galectin-1 Isoform

Galectin-1

 

Galectin-1 Related Products (8):

Cat. No. Product Name Effect Purity
  • HY-19756
    OTX008
    Inhibitor 99.94%
    OTX008 is a selective inhibitor of galectin-1.
  • HY-162561
    GB1908
    Inhibitor 98.94%
    GB1908 is a selective and orally active galectin-1 inhibitor with Ki values of 57 nM and 72 nM for human and mouse galectin-1, respectively. GB1908 displays >50-fold selectivity over galectin-3. GB1908 can be used for the study of lung cancer.
  • HY-163082
    GB1490
    Inhibitor
    GB1490 is an orally active galectin inhibitor with Kd values of 0.4 μM and 2.7 μM for galectin-1 and galectin-3, respectively.
  • HY-157821
    Galectin-4-IN-3
    Inhibitor
    Galectin-4-IN-3 (Compound 11) is a Galectin 4C inhibitor, with a Kd of 160 μM.
  • HY-181648
    Gal-1-IN-1
    Inhibitor
    Gal-1-IN-1 is a potent and selective human galectin-1 (hGal-1) inhibitor with a Ki of 0.022 μM. Gal-1-IN-1 blocks hGal-1 binding to tumor cells and suppresses human galectin-1-induced pre-apoptosis state. Gal-1-IN-1 reduces hGal-1-expressing cancer cell viability. Gal-1-IN-1 can be used for the research of breast cancer.
  • HY-183582
    GB1841
    Inhibitor
    GB1841 is an orally active and selective galectin inhibitor with human galectin-1 Kd of 0.027 μM, human galectin-3 Kd of 0.14 μM, mouse galectin-1 Kd of 0.034 μM and mouse galectin-3 Kd of 1.170 μM. GB1841 can be used for the research of lung cancer.
  • HY-147865
    Apoptosis inducer 8
    Inhibitor
    Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. Apoptosis inducer 8 significantly reduced the gal-1 protein level. Apoptosis inducer 8 is also a PET imaging agent.
  • HY-163407
    Galectin-3-IN-4
    Inhibitor
    Galectin-3-IN-4 (compound 5) is a carboxamide analog. Galectin-3-IN-4 is a potent, selective, and orally bioavailable inhibitor of human and mouse galectin-3, with IC50 values of 21 and 167 nM for hGal-3 and mGal-3, respectively. Galectin-3-IN-4 has IC50 values of 1580 and 2750 nM for hGal-1 and hGal-9, respectively.
Cat. No. Product Name / Synonyms Application Reactivity