1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. TGF-beta Superfamily
  4. Activin/Inhibins Receptor

Activin/Inhibins Receptor

Activins and inhibins are glycoprotein hormones produced mainly in gonads but also in other organs. Activins are dimers of β-subunits (βA:βA, βA:βB, and βB:βB; activin A, activin AB, and activin B, respectively). Inhibins consist of either of the β-subunits dimerized with a common α-subunit (α:βA and α:βB; inhibin A and inhibin B, respectively). They are believed to be important para/autocrine regulators of various cell functions. All known activin/inhibin receptor and follistatin mRNAs were expressed in both fetal and adult adrenals as well as in cultured adrenocortical cells.

Cat. No. Product Name / Synonyms Species Source
  • HY-P72812
    Activin RIA Protein, Human (HEK293, His-Fc)

    Activin receptor type-1; ACTR-I; ALK-2; SKR1; TSR-I; ACVR1; ACVRLK2

    Human HEK293
    Activin A receptor, type I (ACVR1), also known as ALK-2, is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. Activin RIA Protein, Human (HEK293, His-Fc) is produced in HEK293 cells with a C-Terminal His-tag and a C-Terminal Fc-tag . It consists of 124 amino acids (M1-V124).
  • HY-P72813
    ACVR2B Protein, Human (HEK293, Fc)

    Activin receptor type-2B; Activin receptor type IIB; ACTR-IIB; ACVR2B

    Human HEK293
    ACVR2B is a type II member of the TGF-β family of receptor Serine/Threonine kinases. ACVR2B binds to activins and growth differentiation factors (GDF), which in turn activate type I receptors, activating downstream molecule SMAD2/3. ACVR2B Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 134amino acids (M1-T134).
  • HY-P75537
    ACVR2A/Activin RIIA Protein, Human (HEK293, Fc)

    ACVR-2A; Activin receptor type 2A; ACTR-IIA; ACVR2

    Human HEK293
    ACVR2A, also known as Activin RIIA, is an activin type II receptor. On ligand binding, ACVR2A can forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. ACVR2A is a receptor for Activin A, Activin B and Inhibin A. ACVR2A/Activin RIIA Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 134 amino acids (M1-P134).
  • HY-P73069
    Follistatin/FST Protein, Mouse (HEK293, His)

    Follistatin; FS; Activin-binding protein; FST

    Mouse HEK293
    Follistatin (FST) is a regulator of TGFβ family signaling and acts by selectively binding to TGFβ family ligands and preventing ligand binding to the receptor complex. Follistatin has the ability to suppress the follicle stimulating hormone (FSH). Follistatin/FST Protein, Mouse (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 344 amino acids (M1-W344).
  • HY-P74148
    Follistatin/FST Protein, Mouse (CHO, Fc)

    Follistatin; FS; Activin-binding protein; FST

    Mouse CHO
    Follistatin (FST) is a regulator of TGFβ family signaling and acts by selectively binding to TGFβ family ligands and preventing ligand binding to the receptor complex. Follistatin has the ability to suppress the follicle stimulating hormone (FSH). Follistatin/FST Protein, Mouse (CHO, Fc) is produced in CHO cells with a C-Terminal Fc-tag. It consists of 317 amino acids (M1-N317).
  • HY-P73068
    Follistatin/FST Protein, Human (HEK293, Fc)

    Follistatin; FS; Activin-binding protein; FST

    Human HEK293
    Follistatin (FST) is a regulator of TGFβ family signaling and acts by selectively binding to TGFβ family ligands and preventing ligand binding to the receptor complex. Follistatin has the ability to suppress the follicle stimulating hormone (FSH). Follistatin/FST Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.
  • HY-P75536
    ACVR2B Protein, Mouse (HEK293, His)

    Activin receptor type-2B; Activin receptor type IIB; ACTR-IIB; ACVR2B

    Mouse HEK293
    ACVR2B is a type II member of the TGF-β family of receptor Serine/Threonine kinases. ACVR2B binds to activins and growth differentiation factors (GDF), which in turn activate type I receptors, activating downstream molecule SMAD2/3. ACVR2B Protein, Mouse (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 134 amino acids (M1-T134).
  • HY-P75563
    ACVR2A/Activin RIIA Protein, Mouse (HEK293, His)

    ACVR-2A; Activin receptor type 2A; ACTR-IIA; ACVR2

    Mouse HEK293
    ACVR2A, also known as Activin RIIA, is an activin type II receptor. On ligand binding, ACVR2A can forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. ACVR2A is a receptor for Activin A, Activin B and Inhibin A. ACVR2A/Activin RIIA Protein, Mouse (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 134 amino acids (M1-P134).
  • HY-P75571
    Activin RIB/ALK-4 Protein, Human (HEK293, Fc)

    Activin Receptor IB, His; ALK-4; Activin RIB; ACVR1B

    Human HEK293
    Activin RIB, also known as activin receptor type-1B (ACVR1B) or ALK-4, is a type I transmembrane serine/threonine kinase receptor that is part of the TGF-β receptor superfamily. Activin binds to a type II activin receptor (ACVR2or ACVR2B) and then recruits ACVR1B. Activin RIB/ALK-4 Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 126 amino acids (M1-E126).
  • HY-P70315
    Follistatin/FST Protein, Human (HEK293, His)

    rHuFollistatin/FST; follistatin isoform FST317; Follistatin; FS; FSActivin-binding protein; FST

    Human HEK293
    Follistatin (FST) is a regulator of TGFβ family signaling and acts by selectively binding to TGFβ family ligands and preventing ligand binding to the receptor complex. Follistatin has the ability to suppress the follicle stimulating hormone (FSH). Follistatin/FST Protein, Human (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 288 amino acids (G30-N317).
  • HY-P74417
    ALK-7 Protein, Human (HEK293, Fc)

    Activin receptor type IC; ACTR-IC; ACVRLK7; ALK7

    Human HEK293
    ALK-7 is a type I receptor serine-threonine kinase mediate inhibitory as well as stimulatory signals for growth and differentiation by binding to members of the TGF-β superfamily. ALK-7 combined with specific ligands, such as Nodal, activin B and growth differentiation factor (GDF), can activate Smads and other signaling pathways, thereby regulating cell proliferation, differentiation and apoptosis in various cells. ALK-7 Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 113 amino acids (M1-E113).
  • HY-P7480
    ALK-1 Protein, Human (HEK293, Fc)

    rHuActivin Receptor-like Kinase 1, C-Fc; ALK-1; ACVRL1; Activin Receptor-like Kinase 1

    Human HEK293
    ALK-1, also known as ACVRL1, is a type I receptor for TGF-β superfamily with 2 ligands, BMP9 and BMP10. ALK-1 is predominantly expressed in endothelial cells and plays a critical role in regulating developmental and pathological angiogenesis. ALK-1 Protein, Human (97a.a, HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 97 amino acids (D22-Q118).
  • HY-P75516
    ALK-1 Protein, Canine (HEK293, Fc)

    Serine/threonine-protein kinase receptor R3; SKR3; ALK-1; TSR-I; ACVRL1

    Canine HEK293
    ALK-1, also known as ACVRL1, is a type I receptor for TGF-β superfamily with 2 ligands, BMP9 and BMP10. ALK-1 is predominantly expressed in endothelial cells and plays a critical role in regulating developmental and pathological angiogenesis. ALK-1 Protein, Canine (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 119 amino acids (M1-K119).
  • HY-P75569
    ALK-1 Protein, Cynomolgus (HEK293, His)

    Serine/threonine-protein kinase receptor R3; SKR3; ALK-1; TSR-I; ACVRL1

    Cynomolgus HEK293
    ALK-1, also known as ACVRL1, is a type I receptor for TGF-β superfamily with 2 ligands, BMP9 and BMP10. ALK-1 is predominantly expressed in endothelial cells and plays a critical role in regulating developmental and pathological angiogenesis. ALK-1 Protein, Cynomolgus (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 118 amino acids (D22-Q118).
  • HY-P75572
    Activin RIB/ALK-4 Protein, Human (HEK293, His-Fc)

    Activin Receptor IB, His; ALK-4; Activin RIB; ACVR1B

    Human HEK293
    Activin RIB, also known as activin receptor type-1B (ACVR1B) or ALK-4, is a type I transmembrane serine/threonine kinase receptor that is part of the TGF-β receptor superfamily. Activin binds to a type II activin receptor (ACVR2or ACVR2B) and then recruits ACVR1B. Activin RIB/ALK-4 Protein, Human (HEK293, His-Fc) is produced in HEK293 cells with a C-Terminal His-tag and a C-Terminal Fc-tag. It consists of 126 amino acids (S24-E126).
  • HY-P76718
    Activin RIB/ALK-4 Protein, Rat (HEK293, Fc)

    Activin Receptor IB; ALK-4; Activin RIB; ACVR1B

    Rat HEK293
    Activin RIB, also known as activin receptor type-1B (ACVR1B) or ALK-4, is a type I transmembrane serine/threonine kinase receptor that is part of the TGF-β receptor superfamily. Activin binds to a type II activin receptor (ACVR2or ACVR2B) and then recruits ACVR1B. Activin RIB/ALK-4 Protein, Rat (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 126 amino acids (M1-E126).
  • HY-P7456
    ACVR2B Protein, Human (HEK293, His)

    rHuActivin receptor type 2B, His; ACVR-2B; Activin receptor type 2B

    Human HEK293
    ACVR2B is a type II member of the TGF-β family of receptor Serine/Threonine kinases. ACVR2B binds to activins and growth differentiation factors (GDF), which in turn activate type I receptors, activating downstream molecule SMAD2/3. ACVR2B Protein, Human (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 116 amino acids (S19-T134).
  • HY-P7485
    Activin RIB/ALK-4 Protein, Human (HEK293, His)

    rHuActivin Receptor IB, His; ALK-4; Activin RIB; ACVR1B

    Human HEK293
    Activin RIB, also known as activin receptor type-1B (ACVR1B) or ALK-4, is a type I transmembrane serine/threonine kinase receptor that is part of the TGF-β receptor superfamily. Activin binds to a type II activin receptor (ACVR2or ACVR2B) and then recruits ACVR1B. Activin RIB/ALK-4 Protein, Human (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 103 amino acids (S24-E126).
  • HY-P72769
    Activin RIA Protein, Human (HEK293, Fc)

    Receptor protein serine/threonine kinase; ACVR1; ACVR1A; FOP; SKR1; TSRI

    Human HEK293
    Activin A receptor, type I (ACVR1), also known as ALK-2, is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. Activin RIA Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 102 amino acids (D23-V124).
  • HY-P7455
    ACVR2A/Activin RIIA Protein, Human (HEK293, His, solution)

    rHuActivin receptor type 2A, His; ACVR-2A; Activin receptor type 2A

    Human HEK293
    ACVR2A, also known as Activin RIIA, is an activin type II receptor. On ligand binding, ACVR2A can forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. ACVR2A is a receptor for Activin A, Activin B and Inhibin A. ACVR2A/Activin RIIA Protein, Human (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 115 amino acids (A20-P134).
Cat. No. Product Name Effect Purity