2. 同位体標識化合物
  3. Isotope-Labeled Synthetic Intermediates

Isotope-Labeled Synthetic Intermediates

These Stable Isotope-Labeled Synthetic Intermediates play an important role in the synthesis of drugs and drug discovery. MedChemExpress ( MCE ) offers a broad range of Stable Isotope-Labeled Synthetic Intermediates containing different stable isotope atoms, such as deuterium ( 2H, D ), carbon-13 ( 13C ), nitrogen-15 ( 15N ), etc. According to our customers’ requirements, we could provide customized services of different Stable Isotope-Labeled synthetic intermediates from milligrams to kilograms.

Isotope-Labeled Synthetic Intermediates (369):

製品番号 製品名 CAS 番号 純度 構造式
  • HY-18569S
    3-Indoleacetic acid-d5 76937-78-5 99.76%
    3-Indoleacetic acid-d5 is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid-d5 can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates.
    3-Indoleacetic acid-d<sub>5</sub>
  • HY-W015913S
    Pyruvic acid-13C3 sodium

    Sodium 2-oxopropanoate-13C3

    		142014-11-7 99.7%
    Sodium 2-oxopropanoate-13C3 is the 13C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS.
    Pyruvic acid-<sup>13</sup>C<sub>3</sub> sodium
  • HY-I1124
    L-Valine-d8

    L-Valine-d8

    		35045-72-8 99.91%
    L-Valine-d8 is a deuterated form of L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase.
    L-Valine-d<sub>8</sub>
  • HY-B2130S1
    Uric acid-15N2

    Uric acid-15N2

    		62948-75-8 99.95%
    Uric acid-15N2 is the 15N labeled Uric acid. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation.
    Uric acid-<sup>15</sup>N<sub>2</sub>
  • HY-Y0271S2
    Urea-13C,15N2

    Urea-13C,15N2

    		58069-83-3 99.95%
    Urea-13C,15N2 is the 13C and 15N labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
    Urea-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-ER013S
    Sodium carbonate, AR, 99.8%-13C-1 93673-48-4
    Sodium carbonate, AR, 99.8%-13C-1 (Calcined soda, AR, 99.8%-13C-1) is the 13C-labeled Sodium carbonate, AR, 99.8%.
    Sodium carbonate, AR, 99.8%-<sup>13</sup>C-1
  • HY-B0167S
    Salicylic acid-d6 285979-87-5 99.82%
    Salicylic acid-d6 is a deuterium labeled Salicylic acid (HY-B0167). Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation.
    Salicylic acid-d<sub>6</sub>
  • HY-18569S3
    3-Indoleacetic acid-d7 1173020-21-7 99.84%
    3-Indoleacetic acid-d7 is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.
    3-Indoleacetic acid-d<sub>7</sub>
  • HY-19528S
    SAH-d4 ≥99.0%
    SAH-d4 is the deuterium labeled SAH. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM.
    SAH-d<sub>4</sub>
  • HY-W099602S
    Dodecane-d26

    Dodecane-d26

    		16416-30-1 99.6%
    Dodecane-d26 is the deuterium labeled Dodecane.
    Dodecane-d<sub>26</sub>
  • HY-W015967S
    Glycolic acid-d2 75502-10-2 98.54%
    Glycolic acid-d2 is the deuterium labeled Glycolic acid. Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
    Glycolic acid-d<sub>2</sub>
  • HY-Y0271S
    Urea-15N2 2067-80-3 99.80%
    Urea-15N2 is the 15N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
    Urea-<sup>15</sup>N<sub>2</sub>
  • HY-N1902S
    4-Hydroxyphenylacetic acid-d6 100287-06-7 99.16%
    4-Hydroxyphenylacetic acid-d6 is the deuterium labeled 4-Hydroxyphenylacetic acid. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2.
    4-Hydroxyphenylacetic acid-d<sub>6</sub>
  • HY-W142820S
    1,1,3,3-Tetraethoxypropane-d2 105479-86-5 99.23%
    1,1,3,3-Tetraethoxypropane-d2 is the deuterium labeled 1,1,3,3-Tetraethoxypropane.
    1,1,3,3-Tetraethoxypropane-d<sub>2</sub>
  • HY-Y0262S1
    Oxalic acid-13C2 62654-02-8 99.45%
    Oxalic acid-13C2 is the deuterium labeled Oxalic acid, 99% (HY-Y0262). Oxalic Acid is a strong dicarboxylic acid occurring in many plants and vegetables and can be used as an analytical reagent and general reducing agent.
    Oxalic acid-<sup>13</sup>C<sub>2</sub>
  • HY-Y0669S
    Pipecolic acid-d9 790612-94-1 99.9%
    Pipecolic acid-d9 is the deuterium labeled Pipecolic acid. Pipecolic acid is a metabolite of lysine and an important precursor for many useful microbial secondary metabolites. Pipecolic acid slows ferroptosis in diabetic retinopathy by inhibiting the YAP-GPX4 signaling pathway. In addition, Pipecolic acid can be used as a diagnostic marker for pyridoxine-dependent epilepsy.
    Pipecolic acid-d<sub>9</sub>
  • HY-N1380S1
    Guaiacol-d3 74495-69-5 99.0%
    Guaiacol-d3 is the deuterium labeled Guaiacol. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Guaiacol has an anti-inflammatory activity.
    Guaiacol-d<sub>3</sub>
  • HY-132429S
    Potassium 1H-indol-3-yl sulfate-d5 1644451-34-2 99.77%
    Potassium 1H-indol-3-yl sulfate-d5 is the deuterium labeled 3-Indoxyl Sulfate potassium. Potassium 1H-indol-3-yl sulfate is a metabolite of tryptophan, produced by intestinal microorganisms and combined with sulfate in the liver before entering the circulatory system. Potassium 1H-indol-3-yl sulfate is a potent endogenous agonist of the aryl hydrocarbon receptor (AhR) and a urinary toxin. Potassium 1H-indol-3-yl sulfate can be used for research on kidney diseases.
    Potassium 1H-indol-3-yl sulfate-d<sub>5</sub>
  • HY-24385S
    N-Nitrosodipropylamine-d14 93951-96-3 98.48%
    N-Nitrosodipropylamine-d14 is the deuterium labeled N-Nitrosodipropylamine[1].
    N-Nitrosodipropylamine-d<sub>14</sub>
  • HY-W021448S
    Glycocyamine-d2 1173020-63-7 99.90%
    Glycocyamine-d2 (Guanidinoacetic acid-d2) is the deuterium labeled Glycocyamine (HY-W021448). Glycocyamine is a direct precursor of creatine and an orally active energy metabolism regulator and myogenic differentiation inducer. Glycocyamine can activate the Akt/mTOR/S6K signaling pathway via miR-133a-3p and miR-1a-3p, and stimulate the mRNA expression of myogenic differentiation factor 1 (MyoD) and myopoietin (MyoG). Glycocyamine can increase muscle creatine concentration and maintain ATP homeostasis through the creatine phosphate/creatine kinase system. Glycocyamine can be used in research on feed additives for poultry farming.
    Glycocyamine-d<sub>2</sub>