2. Isotope-Labeled Compounds
  3. Isotope-Labeled Synthetic Intermediates

Isotope-Labeled Synthetic Intermediates

These Stable Isotope-Labeled Synthetic Intermediates play an important role in the synthesis of drugs and drug discovery. MedChemExpress ( MCE ) offers a broad range of Stable Isotope-Labeled Synthetic Intermediates containing different stable isotope atoms, such as deuterium ( 2H, D ), carbon-13 ( 13C ), nitrogen-15 ( 15N ), etc. According to our customers’ requirements, we could provide customized services of different Stable Isotope-Labeled synthetic intermediates from milligrams to kilograms.

Isotope-Labeled Synthetic Intermediates (326):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-I1124
    L-Valine-d8 35045-72-8 99.10%
    L-Valine-d8 is a deuterated form of L-Valine. L-Valine-d8 can be used in the labelled synthesis of L-valineamide-d8 intermediate[1]. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[2].
    L-Valine-d<sub>8</sub>
  • HY-18569S
    3-Indoleacetic acid-d5 76937-78-5 99.84%
    3-Indoleacetic acid-d5 is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d5 can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].
    3-Indoleacetic acid-d<sub>5</sub>
  • HY-B2130S1
    Uric acid-15N2 62948-75-8 99.60%
    Uric acid-15N2 is the 15N labeled Uric acid. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation.
    Uric acid-<sup>15</sup>N<sub>2</sub>
  • HY-W015967S
    Glycolic acid-d2 75502-10-2 98.54%
    Glycolic acid-d2 is the deuterium labeled Glycolic acid. Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
    Glycolic acid-d<sub>2</sub>
  • HY-W015913S
    Sodium 2-oxopropanoate-13C3 142014-11-7 99.61%
    Sodium 2-oxopropanoate-13C3 is the 13C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[1][2].
    Sodium 2-oxopropanoate-<sup>13</sup>C<sub>3</sub>
  • HY-136492S
    Acetylclonidine-d4
    Acetylclonidine-d4 is the deuterium labeled Acetylclonidine.
    Acetylclonidine-d<sub>4</sub>
  • HY-131990S
    MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH-d5
    MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH-d5 is deuterated labeled MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH[1].
    MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH-d<sub>5</sub>
  • HY-19528S
    SAH-d4 ≥99.0%
    SAH-d4 is the deuterium labeled SAH. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine[1]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM[2].
    SAH-d<sub>4</sub>
  • HY-B0649S1
    Propofol-d18 1189467-93-3
    Propofol-d18 is the deuterium labeled Propofol. Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission[1].
    Propofol-d<sub>18</sub>
  • HY-W007355S
    Skatole-d3 111399-60-1 ≥98.0%
    Skatole-d3 is the deuterium labeled Skatole. Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38[1].
    Skatole-d<sub>3</sub>
  • HY-B0167S
    Salicylic acid-d6 285979-87-5 99.83%
    Salicylic acid-d6 is a deuterium labeled Salicylic acid. Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation[1].
    Salicylic acid-d<sub>6</sub>
  • HY-Y0781S
    Pyruvic acid-13C sodium 87976-70-3 98.90%
    Pyruvic acid-13C (sodium) is the 13C-labeled Pyruvic acid. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.
    Pyruvic acid-<sup>13</sup>C sodium
  • HY-Y0271S2
    Urea-13C,15N2 58069-83-3 99.10%
    Urea-13C,15N2 is the 13C and 15N labeled Urea[1]. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
    Urea-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-Y0271S
    Urea-15N2 2067-80-3 ≥98.0%
    Urea-15N2 is the 15N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
    Urea-<sup>15</sup>N<sub>2</sub>
  • HY-N0337S
    Eugenol-d3 1335401-17-6 99.86%
    Eugenol-d3 is the deuterium labeled Eugenol. Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation.
    Eugenol-d<sub>3</sub>
  • HY-132429S
    3-Indoxyl Sulfate-d5 potassium 1644451-34-2
    3-Indoxyl Sulfate-d5 (potassium) is the deuterium labeled 3-Indoxyl Sulfate potassium[1].
    3-Indoxyl Sulfate-d<sub>5</sub> potassium
  • HY-W099602S
    Dodecane-d26 16416-30-1 99.83%
    Dodecane-d26 is the deuterium labeled Dodecane[1].
    Dodecane-d<sub>26</sub>
  • HY-18569S3
    3-Indoleacetic acid-d7 1173020-21-7 ≥99.00%
    3-Indoleacetic acid-d7 is the deuterium labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.
    3-Indoleacetic acid-d<sub>7</sub>
  • HY-18569S2
    3-Indoleacetic acid-2,2-d2 24420-86-8 98.06%
    3-Indoleacetic acid-2,2-d2 is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.
    3-Indoleacetic acid-2,2-d<sub>2</sub>
  • HY-N1902S
    4-Hydroxyphenylacetic acid-d6 100287-06-7 98.66%
    4-Hydroxyphenylacetic acid-d6 is the deuterium labeled 4-Hydroxyphenylacetic acid. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2[1].
    4-Hydroxyphenylacetic acid-d<sub>6</sub>