Guaiacol-d3
Based on 1 Customer Validation
Guaiacol-d3 is the deuterium labeled Guaiacol. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Guaiacol has an anti-inflammatory activity.
For research use only. We do not sell to patients.
- Purity: 98.67%
- CAS No.: 74495-69-5
- Formula: C7H5D3O2
- Molecular Weight:127.16
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 74495-69-5
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Unlabeled Cas 90-05-1
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Appearance Liquid (Density: 1.137 g/cm3)
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Molecular Weight 127.16
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Formula C7H5D3O2
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Color Light yellow to light brown
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SMILES
OC1=CC=CC=C1OC([2H])([2H])[2H]
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Synonyms
2-Methoxyphenol-d3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (786.41 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.8641 mL | 39.3205 mL | 78.6411 mL | 196.6027 mL |
| 5 mM | 1.5728 mL | 7.8641 mL | 15.7282 mL | 39.3205 mL | |
| 10 mM | 0.7864 mL | 3.9321 mL | 7.8641 mL | 19.6603 mL | |
| 15 mM | 0.5243 mL | 2.6214 mL | 5.2427 mL | 13.1068 mL | |
| 20 mM | 0.3932 mL | 1.9660 mL | 3.9321 mL | 9.8301 mL | |
| 25 mM | 0.3146 mL | 1.5728 mL | 3.1456 mL | 7.8641 mL | |
| 30 mM | 0.2621 mL | 1.3107 mL | 2.6214 mL | 6.5534 mL | |
| 40 mM | 0.1966 mL | 0.9830 mL | 1.9660 mL | 4.9151 mL | |
| 50 mM | 0.1573 mL | 0.7864 mL | 1.5728 mL | 3.9321 mL | |
| 60 mM | 0.1311 mL | 0.6553 mL | 1.3107 mL | 3.2767 mL | |
| 80 mM | 0.0983 mL | 0.4915 mL | 0.9830 mL | 2.4575 mL | |
| 100 mM | 0.0786 mL | 0.3932 mL | 0.7864 mL | 1.9660 mL |