1. Signaling Pathways
  2. Immunology/Inflammation
  3. COX
  4. COX Isoform

COX

 

COX Related Products (197):

Cat. No. Product Name Effect Purity
  • HY-B1221
    Flufenamic acid
    Inhibitor 99.82%
    Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels.
  • HY-10582
    Flurbiprofen
    Inhibitor 99.98%
    Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities.
  • HY-N7067
    Revaprazan hydrochloride
    Inhibitor 99.98%
    Revaprazan hydrochloride is a novel acid pump antagonist (APA).
  • HY-18342
    Diflunisal
    Inhibitor 99.61%
    Diflunisal (MK-647) is a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients.
  • HY-14397A
    Indomethacin sodium hydrate
    Inhibitor
    Indomethacin (Indometacin) sodium hydrateis a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively.
  • HY-B1452
    Licofelone
    Inhibitor ≥99.0%
    Licofelone (ML-3000) is a dual COX/5-lipoxygenase (5-LOX) inhibitor (IC50=0.21/0.18 μM, respectively) for the treatment of osteoarthritis.
  • HY-W015007
    Metyrosine
    Inhibitor 98.79%
    Metyrosine is a selective tyrosine hydroxylase enzyme inhibitor.
  • HY-N0898A
    (-)-Catechin
    Inhibitor 98.78%
    (-)-Catechin is an isomer of Catechin having a trans 2S,3R configuration at the chiral center.
  • HY-N7148
    γ-Tocopherol
    Inhibitor ≥98.0%
    γ-Tocopherol (D-γ-Tocopherol) is a potent cyclooxygenase (COX) inhibitor.
  • HY-Y0189
    Methyl Salicylate
    Inhibitor
    Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent.
  • HY-124108
    Eicosatetraynoic acid
    Inhibitor ≥99.0%
    Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively).
  • HY-18763
    Indobufen
    Inhibitor 99.98%
    Indobufen is a platelet aggregation inhibitor.
  • HY-B1279
    Metamizole sodium hydrate
    Inhibitor ≥98.0%
    Metamizole sodium hydrate is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX).
  • HY-N0632
    Esculentoside A
    Inhibitor 98.27%
    Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta.
  • HY-107416
    RHC 80267
    Inhibitor 99.51%
    RHC 80267 (U-57908) is a potent and selective inhibitor of diacylglycerol lipase (DAGL) (with IC50 of 4 μM in canine platelets).
  • HY-N0589
    Dehydrodiisoeugenol
    Inhibitor 99.53%
    Dehydrodiisoeugenol is isolated from Myristica fragrans Houtt, shows anti-inflammatory and anti-bacterial actions.
  • HY-B0580A
    (S)-Ketorolac
    Inhibitor 99.62%
    (S)-Ketorolac is a nonsteroidal anti-inflammatory agent.
  • HY-B0230
    Phenylbutazone
    Inhibitor 99.94%
    Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS).
  • HY-B1355A
    Oxyphenbutazone
    Inhibitor ≥99.0%
    Oxyphenbutazone is a Phenylbutazone (HY-B0230) metabolite, with anti-inflammatory effect.
  • HY-B0288B
    Fenoprofen Calcium hydrate
    Inhibitor 99.93%
    Fenoprofen Calcium hydrate is a nonsteroidal, anti-inflammatory antiarthritic agent.